Relation of Treatment Frequency and Duration to Psychotherapeutic Outcome.

2004 ◽  
pp. 134-141 ◽  
Author(s):  
Maurice Lorr
2021 ◽  
Author(s):  
Helena Giannakaki-Zimmermann ◽  
Alexandra Behrndt ◽  
Laura Hoffmann ◽  
Maria-Magdalena Guichard ◽  
Cengiz Tuerksever ◽  
...  

Abstract Purpose: To investigate longer-term functional and morphological outcomes and their predictors in diabetic macular edema (DME) following a treat and extend regimen (TER) without loading dose under ranibizumab. Methods: Patient data were reviewed and analyzed retrospectively over a period of 24 months after initiation of TER. Best-corrected visual acuity (BCVA), treatment frequency as well as quantitative and qualitative Spectral-domain Optical Coherence Tomography parameters were assessed. Results: 118 eyes of 87 patients were included. A mean of 9.742.13 injections in the first and 7.632.29 in the second year were applied. There were significant gains of BCVA and reductions in central retinal thickness from baseline to month 12 and 24 (all p<0.001). Percentage of eyes with an intact inner-/outer segment (IS/OS) junction increased from 15.3% at baseline to 42.1% at month 24 (p<0.001). An intact IS/OS junction at baseline increased the probability of having a dry retina after 12 months by 79.3% (p=0.017) and after 24 months by 88.1% (p=0.040). Less IS/OS disruption at baseline predicted longer maximum recurrence-free treatment intervals at 2 years (r=-0.345, p<0.001) and better BCVA at one year (r=-0.347, p<0.001). Baseline bigger intraretinal cysts were associated with more IS/OS disruption at 24 months (r=0.305, p=0.007). Younger age and lower BCVA at baseline were predictive for a higher BCVA gain at 24 months (p=0.046, p<0.001). Conclusion: Ranibizumab applied in a TER without loading dose in DME significantly improves visual acuity and retinal anatomical structure throughout two years. The evaluated predictors might help to guide routine clinical treatment in DME.


2020 ◽  
Vol 21 ◽  
pp. e00834
Author(s):  
Melia G. Nafus ◽  
Amy A. Yackel Adams ◽  
Scott M. Boback ◽  
Shane R. Siers ◽  
Robert N. Reed

2018 ◽  
Vol 16 (1) ◽  
pp. 43-57 ◽  
Author(s):  
Whitney Shatz ◽  
Jeffrey Aaronson ◽  
Stefan Yohe ◽  
Robert F. Kelley ◽  
Yogeshvar N. Kalia

2019 ◽  
Vol 3 (1) ◽  
pp. 28-31
Author(s):  
Ita Yulita ◽  
Ita Astit Karmawati ◽  
Rahaju Budiarti

This study aimed to compare the effectiveness of strawberry extract with100%, 75%, 50% and 25% concentration in cleaning the extrinsic stain on the teeth. The sample of the study was 32 permanent anterior teeth that were already extracted, consisting of each 16 maxillary and mandibular anterior teeth and all samples have an extrinsic stain. The samples were randomly divided into 4 groups, each group consisting of 8 teeth was treated by applying the strawberry extract with the concentrations of 100%, 75%, 50% and 25%. After 5 minutes, the teeth were rinsed and dried. The study was conducted in vitro for five consecutive days with twice treatment daily. Intensity Score and Extension Score of the stain were measured using the Lobene Stain Index. All samples experienced a decrease in both the Intensity and Extension Scores, the largest decrease in Intensity and Extension Score were obtained from strawberry extracts with concentration of 100%. The significant decrease in the Intensity Score occurs on the third day and continues until the fourth and fifth days, while the significant decrease in the Extention Score occurs on the fourth day and continues until the fifth day. The four group of the strawberry extract concentrations gave a decrease in the score, which distinguishes the treatment frequency. The higher the concentration, the frequency would be less in lowering stain score, whereas at low concentration the decrease of score require more frequency. Keywords: Extrinsic stain, Strawberry extract


2003 ◽  
Vol 50 (3) ◽  
pp. 141-146 ◽  
Author(s):  
Aleksandar Diklic ◽  
Vladan Zivaljevic ◽  
Ivan Paunovic ◽  
Ksenija Krgovic ◽  
Rastko Zivic ◽  
...  

Primary thyroid lymphomas are rare. Surgery is seldom indicated. The aim of the study is to find out the main characteristics of primary thyroid lymphomas in our patients, indications for surgery and the possibility of treatment, frequency and characteristics of rare thyroid tumors. Method: retrospective study of 1044 patient operated for malignant thyroid tumor. Results: From 1995 to may 2003, we operated upon 15 patients with primary thyroid lymphomas, 2 men and 13 women mean age of 50.12 years (from 22 to 74 years), also one patient of age 69 with insular thyroid cancer. Reason for surgery was thyroid tumor in all, compressive disturbances in 9, among them 4 with asphyxia. Radical total thyroidectomy was performed in 4 (26.7%), whole in others some residual tumor tissue was could not be removed in spite of thyroidectomy in 3, hemithyroidectomy in 2, tumor debulking in 5 and only open biopsy was performed in one patient. There was no operative mortality, no postoperative hypocalcaemia and no recurrent nerve palsy. Histological type of tumor was Non-Hodgkin lymphoma in 13 patients, Hodgkin disease in 2 female patients of age 22 and 24. Hashimoto thyroiditis was present in 3 patients. After surgery, 13 patients were treated with chemotherapy, one patient died one month after the operation and one patient refused chemotherapy. Follow-up data are available for 9 patients and the mean follow-up period was 20 months (1-48months). Three patients died after a month, 2 and 3 years after surgery. Six patients are without local relapse. In one patient who refused chemotherapy, a year after thyroid surgery, resection of large intestine was performed because of lymphoma of the colon. Conclusion: Malignant thyroid lymphomas are rare. They present with rapidly growing thyroid tumor, compression and asphyxia. Surgery is only temporarily effective and it is necessary to start with chemo-radiotherapy as soon as possible. Rare forms of thyroid cancer have to be histological recognized in order to choose the best way of treatment.


2018 ◽  
Vol 24 (1) ◽  
pp. 577-580
Author(s):  
Komal Mushtaq ◽  
Shoaib Waqas ◽  
Hafiz Muhammad Asim

Chronic low back pain (CLBP) can be managed by multidisciplinary team approach especially physiotherapy and rehabilitation. In this study, effectiveness of spinal manual therapy (maitland grade I and II mobilization) for CLBP management was assessed. Methods: All subjects in the study were provided maitland grade I and II spinal mobilization for 20 minutes each. A similar treatment frequency was applied and consisted on three sessions per week for 2 continuous weeks. Numeric pain rating scale (NPRS) was applied to assess the pain severity levels before treatment and after treatment. Data were normally distributed and therefore, change in pain intensity was measured by “t” test using SPSS version 23.0. Results: The calculated mean pain score on NPRS before treatment was 3.90 (standard deviation, 0.3038) and after treatment it was 1.65 (standard deviation, 0.8638). The calculated t-value was 12.08 (p value=0.000). Conclusion: These results clearly demonstrate that the maitland G1 and G2 spinal mobilization can be exploited as an effective treatment choice for chronic low back pain.


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