The role of molecular genetics in the postgenomic era.

Author(s):  
Ian W. Craig ◽  
Joseph McClay
Keyword(s):  
2013 ◽  
Vol 16 (1) ◽  
pp. 125-159 ◽  
Author(s):  
Jennifer R Ovenden ◽  
Oliver Berry ◽  
David J Welch ◽  
Rik C Buckworth ◽  
Catherine M Dichmont

Author(s):  
Víctor Martínez-Glez ◽  
Miguel Torres-Martín ◽  
Javier S. Castresana ◽  
Luis Lassaletta ◽  
Juan A. Rey

2020 ◽  
pp. 481-501
Author(s):  
Madhumita Roy Chowdhury ◽  
Anchal Singh ◽  
Sudhisha Dubey

2000 ◽  
Vol 13 (4) ◽  
pp. 377-384 ◽  
Author(s):  
Anurag Tandon ◽  
Ekaterina Rogaeva ◽  
Michael Mullan ◽  
Peter H. St George-Hyslop

2016 ◽  
Vol 18 (6) ◽  
pp. 708-712 ◽  
Author(s):  
Berje Shammassian ◽  
Sunil Manjila ◽  
Efrem Cox ◽  
Kaine Onwuzulike ◽  
Dehua Wang ◽  
...  

Intracranial ectopic salivary gland rests within dural-based lesions are reported very infrequently in the literature. The authors report the unique case of a 12-year-old boy with a cerebellar medulloblastoma positive for sonic hedgehog (Shh) that contained intraaxial mature ectopic salivary gland rests. The patient underwent clinical and radiological monitoring postoperatively, until he died of disseminated disease. An autopsy showed no evidence of salivary glands within disseminated lesions. The intraaxial presence of salivary gland rests and concomitant Shh positivity of the described tumor point to a disorder in differentiation as opposed to ectopic developmental foci, which are uniformly dural based in the described literature. The authors demonstrate the characteristic “papilionaceous” appearance of the salivary glands with mucicarmine stain and highlight the role of Shh signaling in explaining the intraaxial presence of seromucous gland analogs. This article reports the first intraaxial posterior fossa tumor with heterotopic salivary gland rests, and it provides molecular and embryopathological insights into the development of these lesions.


Sign in / Sign up

Export Citation Format

Share Document