Will advances in prevention technologies make behavioral counseling obsolete? Lessons learned from HIV vaccine trials.

2004 ◽  
pp. 255-266
Author(s):  
Mallory O. Johnson
Keyword(s):  
Lessons Learned ◽  
Hiv Vaccine ◽  
Behavioral Counseling ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials

scholarly journals Lessons learned from human HIV vaccine trials

2017 ◽  
Vol 12 (3) ◽  
pp. 216-221 ◽  
Author(s):  
Justin Pollara ◽  
David Easterhoff ◽  
Genevieve G. Fouda
Keyword(s):  
Lessons Learned ◽  
Hiv Vaccine ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials

scholarly journals A qualitative assessment of perspectives on the inclusion of adolescents in HIV vaccine trials in South Africa

2010 ◽  
Vol 21 (3) ◽  
pp. 172-176 ◽  
Author(s):  
H B Jaspan ◽  
N F Soka ◽  
C Mathews ◽  
A J Flisher ◽  
D Mark ◽  
...  
Keyword(s):  
South Africa ◽  
Hiv Vaccine ◽  
Qualitative Assessment ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials

Willingness to participate in HIV vaccine research in a peri-urban South African community

2006 ◽  
Vol 17 (3) ◽  
pp. 176-179 ◽  
Author(s):  
J Smit ◽  
K Middelkoop ◽  
L Myer ◽  
S Seedat ◽  
L-G Bekker ◽  
...  
Keyword(s):  
South African ◽  
Hiv Vaccine ◽  
Sub Saharan Africa ◽  
Willingness To Participate ◽  
Vaccine Research ◽  
Substantial Impact ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials ◽  
Urban South ◽  
African Community

Research on willingness to participate in HIV vaccine trials is important in preparations for HIV vaccine research, but there are few data from sub-Saharan Africa. We interviewed 198 individuals in a peri-urban South African community immediately after enrolment into an HIV vaccine preparedness study on their willingness to participate in hypothetical vaccine trials. Overall 23% of participants ( n = 46) said that they would be willing to participate in an HIV vaccine trial. Willingness was associated with increasing age, male gender, and increasing knowledge about vaccines generally and HIV vaccines specifically. In multivariate analysis, a 1-unit increase in HIV vaccine knowledge score was associated with a 10-fold increase in willingness to participate (adjusted odds ratio, 10.72, 95% confidence intervals: 4.40–26.12). These results suggest that while willingness to participate in HIV vaccine trials is relatively low in this setting, educational campaigns may have a substantial impact on individuals' willingness to participate in research.

scholarly journals Contraceptive Use in Women Enrolled into Preventive HIV Vaccine Trials: Experience from a Phase I/II Trial in East Africa

PLoS ONE ◽  
2009 ◽  
Vol 4 (4) ◽  
pp. e5164 ◽  
Author(s):  
Hannah Kibuuka ◽  
David Guwatudde ◽  
Robert Kimutai ◽  
Lucas Maganga ◽  
Leonard Maboko ◽  
...  
Keyword(s):  
Phase I ◽  
East Africa ◽  
Contraceptive Use ◽  
Hiv Vaccine ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials

scholarly journals “Why Don’t You Go Into Suburbs? Why Are You Targeting Us?”: Trust and Mistrust in HIV Vaccine Trials in South Africa

2018 ◽  
Vol 13 (5) ◽  
pp. 525-536 ◽  
Author(s):  
Siyabonga Thabethe ◽  
Catherine Slack ◽  
Graham Lindegger ◽  
Abigail Wilkinson ◽  
Douglas Wassenaar ◽  
...  
Keyword(s):  
Vaccine Trial ◽  
Hiv Vaccine ◽  
Community Advisory Board ◽  
Future Research ◽  
Community Members ◽  
Group Discussions ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials ◽  
Community Stakeholders ◽  
Site Staff

Trust is a key element of high-quality stakeholder relations, which are themselves essential for the success of HIV vaccine trials. Where trust is absent, community stakeholders might not volunteer to become involved in key trial activities, and potential participants might not volunteer for enrollment. We explored site staff and Community Advisory Board (CAB) members’ experiences of trust/mistrust among community members and potential participants. We analyzed 10 focus group discussions with site staff and CAB members at two active South African HIV vaccine trial sites. We report on key characteristics perceived to contribute to the trustworthiness of communicators, as well as factors associated with mistrust. Attributes associated with trustworthy communicators included shared racial identity, competence, and independence (not being “captured”). Key foci for mistrust included explanations about site selection, stored samples, vaccination, and Vaccine Induced Sero-Positivity (VISP). Our findings suggest that community members’ trust is not necessarily global, in which trials are trusted or not; rather, it appears fairly nuanced and is impacted by various perceived attributes of communicators and the information they provide. We make recommendations for clinical trial site stakeholders invested in building trust and for future research into trust at these sites.

scholarly journals Defining blood processing parameters for optimal detection of cryopreserved antigen-specific responses for HIV vaccine trials

2007 ◽  
Vol 322 (1-2) ◽  
pp. 57-69 ◽  
Author(s):  
Marta Bull ◽  
Deborah Lee ◽  
Jason Stucky ◽  
Ya-Lin Chiu ◽  
Abbe Rubin ◽  
...  
Keyword(s):  
Processing Parameters ◽  
Hiv Vaccine ◽  
Optimal Detection ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials ◽  
Blood Processing

Community Members' Perceptions of Enablers and Inhibitors to Participation in HIV Vaccine Trials

2006 ◽  
Vol 36 (4) ◽  
pp. 734-761 ◽  
Author(s):  
Anthea Lesch ◽  
Zuhayr Kafaar ◽  
Ashraf Kagee ◽  
Leslie Swartz
Keyword(s):  
Hiv Vaccine ◽  
Community Members ◽  
Hiv Vaccine Trials ◽  
Vaccine Trials
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