Longitudinal changes: Cognitive, behavioral, and affective patterns in Alzheimer's disease.

1986 ◽  
pp. 294-301 ◽  
Author(s):  
Wilma G. Rosen ◽  
Richard C. Mohs ◽  
Kenneth L. Davis
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Behavioral ◽  
Longitudinal Changes

Longitudinal Changes in Individual BrainAGE in Healthy Aging, Mild Cognitive Impairment, and Alzheimer’s Disease

GeroPsych ◽  
2012 ◽  
Vol 25 (4) ◽  
pp. 235-245 ◽  
Author(s):  
Katja Franke ◽  
Christian Gaser
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Healthy Aging ◽  
Brain Aging ◽  
Elderly Subjects ◽  
Additional Increase ◽  
Longitudinal Changes ◽  
Novel Method ◽  
The Brain

We recently proposed a novel method that aggregates the multidimensional aging pattern across the brain to a single value. This method proved to provide stable and reliable estimates of brain aging – even across different scanners. While investigating longitudinal changes in BrainAGE in about 400 elderly subjects, we discovered that patients with Alzheimer’s disease and subjects who had converted to AD within 3 years showed accelerated brain atrophy by +6 years at baseline. An additional increase in BrainAGE accumulated to a score of about +9 years during follow-up. Accelerated brain aging was related to prospective cognitive decline and disease severity. In conclusion, the BrainAGE framework indicates discrepancies in brain aging and could thus serve as an indicator for cognitive functioning in the future.

scholarly journals Longitudinal changes in hippocampal network connectivity in Alzheimer's disease

2021 ◽  
Author(s):  
Sophie Dautricourt ◽  
Robin Flores ◽  
Brigitte Landeau ◽  
Géraldine Poisnel ◽  
Matthieu Vanhoutte ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Network Connectivity ◽  
Longitudinal Changes ◽  
Hippocampal Network

scholarly journals Longitudinal changes of tau PET imaging in relation to hypometabolism in prodromal and Alzheimer’s disease dementia

2017 ◽  
Vol 23 (7) ◽  
pp. 1666-1673 ◽  
Author(s):  
K Chiotis ◽  
L Saint-Aubert ◽  
E Rodriguez-Vieitez ◽  
A Leuzy ◽  
O Almkvist ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Pet Imaging ◽  
Longitudinal Changes ◽  
Tau Pet ◽  
Alzheimer’S Disease Dementia ◽  
Tau Pet Imaging

Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease

Neurology ◽  
1998 ◽  
Vol 50 (5) ◽  
pp. 1222-1230 ◽  
Author(s):  
J. C. Morris ◽  
P. A. Cyrus ◽  
J. Orazem ◽  
J. Mas ◽  
F. Bieber ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Behavioral ◽  
Global Function
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