The effects of cerebral lesions subsequent to the formation of the maze habit: Localization of the habit.

2004 ◽  
pp. 86-108
Author(s):  
K. S. Lashley
Keyword(s):  
Cerebral Lesions ◽  
Maze Habit

Behavioral Changes Following Radiation: I. Study of Retention of a Partially Learned Maze Habit

1951 ◽  
Author(s):  
Sylvan J. Kaplan ◽  
C. Downing Tait ◽  
Partick D. Wall ◽  
Robert B. Payne
Keyword(s):  
Behavioral Changes ◽  
Maze Habit

When It Is Not MS…—Differential Diagnosis of Optic Neuritis and Multifocal Inflammatory Cerebral Lesions in an Adolescent

2017 ◽  
Vol 48 (S 01) ◽  
pp. S1-S45
Author(s):  
T. Deba ◽  
J. Althaus ◽  
O. Schwartz ◽  
J. Penning ◽  
D. Holzinger ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Optic Neuritis ◽  
Cerebral Lesions

Ultrasound-guided needle biopsies in deep cerebral lesions

2008 ◽  
Vol 39 (01) ◽  
Author(s):  
K Mursch ◽  
H Allouch ◽  
J Behnke-Mursch
Keyword(s):  
Ultrasound Guided ◽  
Cerebral Lesions

Brain MRI-findings in Ph - negative myeloproliferative disorders

2019 ◽  
Vol 91 (7) ◽  
pp. 29-34 ◽  
Author(s):  
M M Tanashyan ◽  
A L Melikyan ◽  
P I Kuznetsova ◽  
A A Raskurazhev ◽  
A A Shabalina ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Sinus Thrombosis ◽  
Cerebral Arteries ◽  
Brain Mri ◽  
Myeloproliferative Disorders ◽  
Cerebral Venous Sinus Thrombosis ◽  
Mri Findings ◽  
Cerebral Lesions ◽  
Cerebrovascular Pathology ◽  
Underlying Mechanisms

Myeloproliferative disorders (MPD) are accompanied by a high proportion of thrombotic complications, which may lead to cerebrovascular disease (CVD). Aim. To describe MRI-findings in patients with Ph - negative MPD and evaluate any cerebrovascular disease. Materials and methods. We included 104 patients with Ph - negative MPD (age varied between 20 and 58) with clinical correlates of cerebrovascular pathology. Results. Brain MRI showed post - stroke lesions in 20% of patients (7 hemispheric infarcts due to thrombotic occlusion of one of the large cerebral arteries, 14 - cortical infarcts). 37 patients (36%) had vascular cerebral lesions. Cerebral venous sinus thrombosis occurred in 5 patients - in 7% (n=3) of patients with polycythemia vera and 5% (n=2) - in patients with essential thrombocythemia. The incidence of vascular cerebral lesions was associated with higher levels of the following: erythrocyte, platelet count, fibrinogen, and with the decrease in fibrinolytic activity, as well. Conclusion. The pioneering results of the study include the description and analysis of brain MRI-findings in patients with Ph - negative MPD. The underlying mechanisms of cerebrovascular pathology in these patients are associated with certain blood alterations (particularly, hemorheology) which present a major risk factor.

Intraoperative monitoring of olfactory function: a feasibility study

2020 ◽  
Vol 132 (5) ◽  
pp. 1659-1664 ◽  
Author(s):  
Shahan Momjian ◽  
Rémi Tyrand ◽  
Basile N. Landis ◽  
Colette Boëx
Keyword(s):  
Evoked Potentials ◽  
General Anesthesia ◽  
Intraoperative Neuromonitoring ◽  
Olfactory Function ◽  
Chemical Senses ◽  
Cerebral Lesions ◽  
Artifact Rejection ◽  
Rejection Criterion ◽  
Olfactory Stimuli ◽  
Anterior Fossa

OBJECTIVEIntraoperative neuromonitoring of the chemical senses (smell and taste) has never been performed. The objective of this study was to determine if olfactory-evoked potentials could be obtained intraoperatively under general anesthesia.METHODSA standard olfactometer was used in the surgical theater with hydrogen sulfide (4 ppm, 200 msec). Olfactory-evoked potentials were recorded in 8 patients who underwent neurosurgery for resection of cerebral lesions. These patients underwent routine target-controlled propofol and sufentanil general anesthesia. Frontal, temporal, and parietal scalp subdermal electrodes were recorded ipsilaterally and contralaterally at the site of the surgery. Evoked potentials were computed if at least 70 epochs (0.5–100 Hz) satisfying the artifact rejection criterion (threshold 45 μV) could be extracted from signals of electrodes.RESULTSContributive recordings were obtained for 5 of 8 patients (3 patients had fewer than 70 epochs with an amplitude < 45 μV). Olfactory-evoked potentials showed N1 responses (mean 442.8 ± 40.0 msec), most readily observed in the patient who underwent midline anterior fossa neurosurgery. No component of later latencies could be recorded consistently.CONCLUSIONSThe study confirms that olfactory-evoked potentials can be measured in response to olfactory stimuli under general anesthesia. This demonstrates the feasibility of recording olfactory function intraoperatively and opens the potential for neuromonitoring of olfactory function during neurosurgery.

What Has Direct Cortical and Subcortical Electrostimulation Taught Us about Neurolinguistics?

2019 ◽  
pp. 185-211
Author(s):  
Hugues Duffau
Keyword(s):  
White Matter ◽  
Large Scale ◽  
Functional Neuroimaging ◽  
Great Accuracy ◽  
Subcortical White Matter ◽  
Cerebral Lesions ◽  
Physiological Basis ◽  
Postoperative Mri ◽  
The Brain

Investigating the neural and physiological basis of language is one of the most important challenges in neurosciences. Direct electrical stimulation (DES), usually performed in awake patients during surgery for cerebral lesions, is a reliable tool for detecting both cortical and subcortical (white matter and deep grey nuclei) regions crucial for cognitive functions, especially language. DES transiently interacts locally with a small cortical or axonal site, but also nonlocally, as the focal perturbation will disrupt the entire subnetwork sustaining a given function. Thus, in contrast to functional neuroimaging, DES represents a unique opportunity to identify with great accuracy and reproducibility, in vivo in humans, the structures that are actually indispensable to the function, by inducing a transient virtual lesion based on the inhibition of a subcircuit lasting a few seconds. Currently, this is the sole technique that is able to directly investigate the functional role of white matter tracts in humans. Thus, combining transient disturbances elicited by DES with the anatomical data provided by pre- and postoperative MRI enables to achieve reliable anatomo-functional correlations, supporting a network organization of the brain, and leading to the reappraisal of models of language representation. Finally, combining serial peri-operative functional neuroimaging and online intraoperative DES allows the study of mechanisms underlying neuroplasticity. This chapter critically reviews the basic principles of DES, its advantages and limitations, and what DES can reveal about the neural foundations of language, that is, the large-scale distribution of language areas in the brain, their connectivity, and their ability to reorganize.

Concept Attainment of Human Adults with Lateralized Cerebral Lesions

1962 ◽  
Vol 14 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Donald G. Doehring ◽  
Ralph M. Reitan
Keyword(s):  
Cerebral Lesions ◽  
Concept Attainment ◽  
Human Adults
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