Pharmacological treatment of depressive disorders.

2019 ◽  
pp. 141-164
Author(s):  
Liisa Hantsoo ◽  
Sarah Mathews
Keyword(s):  
Pharmacological Treatment ◽  
Depressive Disorders

Spatio-visual working memory effectiveness and depression levels after pharmacological therapy with ssri - preliminary study

2011 ◽  
Vol 26 (S2) ◽  
pp. 627-627
Author(s):  
M. Talarowska ◽  
A. Florkowski ◽  
D. Berent ◽  
P. Gałecki
Keyword(s):  
Working Memory ◽  
Visual Working Memory ◽  
Test Performance ◽  
Pharmacological Treatment ◽  
Depressive Disorders ◽  
Antidepressant Treatment ◽  
Pharmacological Therapy ◽  
List Type ◽  
Negative Effects ◽  
Performance Levels

IntroductionWorking memory dysfunctions are observed in patients with recurrent depressive disorders. These deficits exert negative effects not only on psychological test performance levels but also on the capacity of affected patients to cope with everyday life situations, as well as on decreased remission levels.AimThe goal of the study was to identify possible associations between spatio-visual working memory, evaluated on admission, with the remission degree, assessed after 8-week pharmacotherapy with SSRI in a group of patients with diagnosed depression.Methods141 subjects were examined (patients with depressive disorders, DD: n = 86, healthy subjects, CG: n = 55). Trail Making Test by Reitan (TMT) was used.ResultsCG obtained higher results vs. DD-I patients (the evaluation started on the therapy onset) in TMT A/time (p = 0.09), TMT B/time (p = 0.009). CG demonstrated better results than DD-II patients (following eight weeks of pharmacological treatment) in TMT A (p = 0.11), TMT B (p = 0.85). Compared to DD-I group, DD-II group achieved better results in TMT A (p < 0.001) and TMT B (p < 0.001). The lowest performance levels in TMT A and TMT B may have been related to the highest depression levels after pharmacological treatment.Conclusions1.Depressive disorders are associated with deteriorated efficiency of visual working memory.2.Antidepressant treatment resulted in improved of visual working memory.3.The better performance in TMT on the first day of treatment may have influenced the noted reduction in severity of depressive symptoms after treatment with SSRI.

A model to incorporate genetic testing (5-HTTLPR) in pharmacological treatment of major depressive disorders

2011 ◽  
Vol 12 (7) ◽  
pp. 501-515 ◽  
Author(s):  
Alessandro Serretti ◽  
Paolo Olgiati ◽  
Emanuele Bajo ◽  
Marco Bigelli ◽  
Diana De Ronchi
Keyword(s):  
Genetic Testing ◽  
Pharmacological Treatment ◽  
Depressive Disorders ◽  
Major Depressive ◽  
Major Depressive Disorders

Social adjustment in female outpatients with depressive disorders under pharmacological treatment

2016 ◽  
Vol 26 ◽  
pp. S404
Author(s):  
M.C. Pirlog ◽  
I. Marinescu ◽  
I. Udristoiu ◽  
A. Chirita ◽  
F. Militaru ◽  
...  
Keyword(s):  
Social Adjustment ◽  
Pharmacological Treatment ◽  
Depressive Disorders

Potential Mechanisms and Clinical Effectiveness of Acupuncture in Depression

2021 ◽  
Vol 19 ◽  
Author(s):  
Na-Na Yang ◽  
Lu-Lu Lin ◽  
Yue-Jie Li ◽  
Hong-Ping Li ◽  
Yan Cao ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Pharmacological Treatment ◽  
Depressive Disorders ◽  
Common Mental Disorder ◽  
Clinical Effectiveness ◽  
Brain Inflammation ◽  
Pharmacological Interventions ◽  
Adjunct Treatment ◽  
Animal Models Of Depression ◽  
Post Stroke Depression

: Major depressive disorder is the most common mental disorder with a significant economic burden and limited treatments. Acupuncture has emerged as a promising non-pharmacological treatment for reducing depressive symptoms. However, the potential mechanisms and clinical effectiveness of acupuncture are not fully understood. The aim of this review was to: (1) summarize the available evidence on the mechanisms and clinical effectiveness of acupuncture for depression, and then (2) compare with pharmacological interventions, guiding future studies. Studies with animal models of depression and patients have shown that acupuncture could increase hippocampal and network neuroplasticity and decrease brain inflammation, and so has the potential to alleviate depressive disorders. Overall clinical studies indicated that acupuncture could relieve primary depression, particularly milder cases, and was helpful in the management of post-stroke depression, pain-related depression, and postpartum depression both as an isolated and adjunct treatment. It was emphasized that acupuncture combined with antidepressant pharmacological treatment not only enhanced the improvement of primary and secondary depressive symptoms but also reduced the side effects of the medical treatment-the main cause for high dropout rates with drug treatment. In summary, substantial evidence from animal and human researches supported the beneficial effect of acupuncture in depression. However, most clinical trials of acupuncture were small, and it is unclear whether their findings can be generalized; thus, more studies are needed.

Pharmacological treatment of unipolar depressive disorders: summary of WFSBP guidelines

2017 ◽  
Vol 21 (3) ◽  
pp. 166-176 ◽  
Author(s):  
Michael Bauer ◽  
Emanuel Severus ◽  
Hans-Jürgen Möller ◽  
Allan H. Young ◽  
Keyword(s):  
Pharmacological Treatment ◽  
Depressive Disorders

Non-Pharmacological Treatment of Depressive Disorders: A Review of Evidence-Based Treatment Options

2012 ◽  
Vol 7 (2) ◽  
pp. 141-149 ◽  
Author(s):  
J. Dirmaier ◽  
M. Steinmann ◽  
T. Krattenmacher ◽  
B. Watzke ◽  
D. Barghaan ◽  
...  
Keyword(s):  
Pharmacological Treatment ◽  
Depressive Disorders ◽  
Treatment Options ◽  
Evidence Based ◽  
Evidence Based Treatment
Sign in / Sign up

Export Citation Format

Share Document