Taxonomy of some Antarctic Bacillus And Corynebacterium species

Author(s):  
Joseph M. Madden ◽  
Susan K. Siegel ◽  
Roy M. Johnson
2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Anna Bläckberg ◽  
Linn Falk ◽  
Karl Oldberg ◽  
Lars Olaison ◽  
Magnus Rasmussen

Abstract Background Corynebacterium species are often dismissed as contaminants in blood cultures, but they can also cause infective endocarditis (IE), which is a severe condition. Antibiotic resistance of corynebacteria is increasing making treatment challenging. Reports on IE caused by Corynebacterium species are scarce and more knowledge is needed. Methods Cases of IE caused by Corynebacterium species were identified through the Swedish Registry of Infective Endocarditis. Isolates were collected for species redetermination by matrix-assisted laser desorption ionization-time of flight and for antibiotic susceptibility testing using Etests. Results Thirty episodes of IE due to Corynebacterium species were identified between 2008 and 2017. The median age of patients was 71 years (interquartile range, 60–76) and 77% were male. Corynebacterium striatum (n = 11) was the most common IE causing pathogen followed by Corynebacterium jeikeium (n = 5). Surgery was performed in 50% and in-hospital mortality rate was 13%. Patients with IE caused by Corynebacterium species were significantly more likely to have prosthetic valve endocarditis (70%), compared with patients with IE due to Staphylococcus aureus or non-beta-hemolytic streptococci (14% and 26%, respectively) (P < .0001). Vancomycin was active towards all Corynebacterium isolates, whereas resistance towards penicillin G was common. Conclusions Corynebacterium species cause IE, where prosthetic valves are mainly affected and surgery is often performed. Corynebacterium striatum is an important causative agent of IE within the genus. Antibiotic resistance of corynebacteria is relatively common but resistance towards vancomycin could not be detected in vitro.


1979 ◽  
Vol 182 (3) ◽  
pp. 827-836 ◽  
Author(s):  
D C Billington ◽  
B T Golding ◽  
S B Primrose

Methods are described for identifying the 2,4-dinitrophenylhydrazones of 4-methylthio-2-oxobutanoate by means of t.l.c., n.m.r. and mass spectroscopy. By using these methods 4-methylthio-2-oxobutanoate, a putative intermediate in the biosynthesis of ethylene from methionine, has been identified in culture fluids of Aeromonas hydrophila B12E and a coryneform bacterium D7F grown in the presence of methionine. Relative to 4-methylthio-2-oxobutanoate, the yield of 3-(methylthio)propanal (methional) from the same cultures was less than 1%. Because 4-[2H]methylthio-2-oxobutanoate was obtained from cultures grown on [Me-2H]methionine, the 4-methylthio-2-oxobutanoate must be derived from methionine. By means of t.l.c. alone, 4-methylthio-2-oxobutanoate was identified in the culture fluids of a range of bacteria, the yeast Saccharomyces cerevisiae and the fungus Penicillium digitatum. A photochemical assay developed for 4-methylthio-2-oxobutanoate shows it to be a product of the metabolism of methionine by Escherichia, Pseudomonas, Bacillus, Acinetobacter, Aeromonas, Rhizobium and Corynebacterium species.


1973 ◽  
Vol 37 (10) ◽  
pp. 2245-2249 ◽  
Author(s):  
Mutsuo SHIMAMURA ◽  
Juichi YOSHITAKE ◽  
Tomio IMAI

2020 ◽  
pp. 1-3
Author(s):  
Mrudul Randive ◽  
Ankita Mohanty ◽  
Sujata Baveja

Introduction: Diphtheria is an acute, highly infectious and previously endemic disease. Due to the vaccine preventable nature of the disease and initial steady decline, not much attention had been given towards this disease. Recent increase in the number of clinically suspected and laboratory confirmed cases of diphtheria have been observed in our laboratory. Aims and objectives: To study the status of resurgence of the disease in a tertiary care hospital of Mumbai. Materials and methods: 76 throat swabs and 1 slough material from 57 clinically suspected cases of diphtheria over a period of one and a half year from July 2018 to December 2019 were obtained and were processed for microscopy and culture for Corynebacterium species by standard microbiological techniques. Results: Eighteen (23.37%) out of 77 samples yielded Corynebacterium species on culture. Out of 57 suspected patients, 11 were culture confirmed diphtheria (19.29%). None of the patients were less than 5 years of age, 55% were between 5 and 9 years and 45% were above 10 years of age with a total female preponderance of 64%. The immunization status was unclear in 27% cases. All the smear and/or culture positive cases were informed immediately to the clinicians so that the patients could be transferred to the Infectious disease hospital for further management. Conclusion: The study has shown an increase in the number of Diphtheria cases in a metropolitan city, which is a cause of concern in healthcare. There is also a shift in age to older children (> 5 years). The study also highlights the need for confirmation of toxin production to facilitate early information to the treating clinicians.


Sign in / Sign up

Export Citation Format

Share Document