scholarly journals Three-Dimensional Ring Current Decay Model

1995 ◽  
Vol 100 (A6) ◽  
pp. 9619 ◽  
Author(s):  
Mei-Ching Fok ◽  
Thomas E. Moore ◽  
Janet U. Kozyra ◽  
George C. Ho ◽  
Douglas C. Hamilton
Keyword(s):  
Ring Current ◽  
Three Dimensional ◽  
Current Decay ◽  
Decay Model

scholarly journals The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold

2015 ◽  
Vol 146 (1) ◽  
pp. 15-36 ◽  
Author(s):  
Giovanni Gonzalez-Gutierrez ◽  
Claudio Grosman
Keyword(s):  
Quaternary Ammonium ◽  
Time Course ◽  
Three Dimensional ◽  
Mouse Muscle ◽  
Current Decay ◽  
Quaternary Ammonium Cations ◽  
Inward Currents ◽  
Time Courses ◽  
Extracellular Side ◽  
Invariant Functional

The superfamily of pentameric ligand-gated ion channels (pLGICs) is unique among ionotropic receptors in that the same overall structure has evolved to generate multiple members with different combinations of agonist specificities and permeant-ion charge selectivities. However, aside from these differences, pLGICs have been typically regarded as having several invariant functional properties. These include pore blockade by extracellular quaternary-ammonium cations in the micromolar-to-millimolar concentration range (in the case of the cation-selective members), and a gain-of-function phenotype, which manifests as a slower deactivation time course, as a result of mutations that reduce the hydrophobicity of the transmembrane pore lining. Here, we tested this notion on three distantly related cation-selective members of the pLGIC superfamily: the mouse muscle nicotinic acetylcholine receptor (nAChR), and the bacterial GLIC and ELIC channels. Remarkably, we found that, whereas low millimolar concentrations of TMA+ and TEA+ block the nAChR and GLIC, neither of these two quaternary-ammonium cations blocks ELIC at such concentrations; instead, both carry measurable inward currents when present as the only cations on the extracellular side. Also, we found that, whereas lidocaine binding speeds up the current-decay time courses of the nAChR and GLIC in the presence of saturating concentrations of agonists, the binding of lidocaine to ELIC slows this time course down. Furthermore, whereas mutations that reduce the hydrophobicity of the side chains at position 9′ of the M2 α-helices greatly slowed the deactivation time course of the nAChR and GLIC, these mutations had little effect—or even sped up deactivation—when engineered in ELIC. Our data indicate that caution should be exercised when generalizing results obtained with ELIC to the rest of the pLGICs, but more intriguingly, they hint at the possibility that ELIC is a representative of a novel branch of the superfamily with markedly divergent pore properties despite a well-conserved three-dimensional architecture.

scholarly journals Another way of deriving the ring current decay time during disturbed periods

1995 ◽  
Vol 38 (2) ◽  
Author(s):  
M. M. Zossi de Artigas ◽  
J. R. Manzano
Keyword(s):  
Ring Current ◽  
Coupling Parameter ◽  
Life Time ◽  
Recovery Phase ◽  
Main Phase ◽  
Physical Analysis ◽  
Inner Magnetosphere ◽  
Current Decay ◽  
The Many ◽  
Energy Dissipated

Coupling parameter, E, and the total energy dissipated by the magnetosphere, UT, are determined for six disturbed periods, following three known criteria for UT computation. It is observed that UT exceeds E for Dst < -90 nT, for alI models. Differences between models reside on the estimated valnes for the particles' life time il1 the equatorial ring current. The values of TR, used in the models, are small during the main phase of the di."turbance, in disagreement with the charge exchange life time of the majority species, H+ and O'-. Based on this conclusion, a different criterion to calculate TR is proposed, differentiating the different stages of the perturbation. TR is calculated, for the main phase of the storm, from the rate of energy deposition estimation, Q, in the ring current. For Dst recovery phase, the vallles are obtained from a ring current decay law computation. The UTvu calculated, physically more coherent with the processes occurring during the event, is now smaller than expected. In this sense, it is understood that the power generated by the solar wind-magnetosphere dy- namo, should also be distributed in the inner magnetosphere, auroral zones and equatorial ring current, as in the outer magnetosphere, plasmoids in the tail shot in antisolar direction. A further adjustment of E, with the Chapman-Ferraro distance, 10' variable, has been made. Although the reslllts, improve the estimation of E, they are sti!l smaller than UT, except UTNU, for some disturbed periods. This result indicates the uncertainty in the computation of the input energy, by using the many expressions proposed in the literature, which are always presented as laws proportional to a given group of parameters, with an unknown factor of proportionality, which deserves more detailed physical analysis.

scholarly journals Energetic ion injection and formation of the storm-time symmetric ring current

2006 ◽  
Vol 24 (12) ◽  
pp. 3547-3556 ◽  
Author(s):  
L. Xie ◽  
Z. Y. Pu ◽  
X. Z. Zhou ◽  
S. Y. Fu ◽  
Q.-G. Zong ◽  
...  
Keyword(s):  
Electric Field ◽  
Ring Current ◽  
Particle Trajectory ◽  
Three Dimensional ◽  
Extensive Study ◽  
Current Injection ◽  
Ion Injection ◽  
Convection Electric Field ◽  
Trajectory Calculations ◽  
Current Region

Abstract. An extensive study of ring current injection and intensification of the storm-time ring current is conducted with three-dimensional (3-D) test particle trajectory calculations (TPTCs). The TPTCs reveal more accurately the process of ring current injection, with the main results being the following: (1) an intense convection electric field can effectively energize and inject plasma sheet particles into the ring current region within 1–3 h. (2) Injected ions often follow chaotic trajectories in non-adiabatic regions, which may have implications in storm and ring current physics. (3) The shielding electric field, which arises as a consequence of enhanced convection and co-exists with the injection and convection electric field, may cause the original open trajectories of injected ions with higher energy to change into closed ones, thus playing a role in the formation of the symmetric ring current.

Ring current decay

2020 ◽  
pp. 181-223
Author(s):  
Vania K. Jordanova
Keyword(s):  
Ring Current ◽  
Current Decay

scholarly journals Global Aromaticity at the Nanoscale

2019 ◽  
Author(s):  
Michel Rickhaus ◽  
Michael Jirasek ◽  
Lara Tejerina ◽  
Henrik Gotfredsen ◽  
Martin D. Peeks ◽  
...  
Keyword(s):  
Small Molecules ◽  
Organic Semiconductors ◽  
Oxidation State ◽  
Single Molecule ◽  
Ring Current ◽  
Electronic Devices ◽  
Three Dimensional ◽  
Average Oxidation State ◽  
Ring Currents ◽  
Cyclic Molecule

<div><p>Aromaticity is an important concept for predicting electronic delocalisation in molecules, particularly for designing organic semiconductors and single-molecule electronic devices. It is most simply defined by the ability of a cyclic molecule to sustain a ring current when placed in a magnetic field. Hückel’s rule states that if a ring has [4n+2] π-electrons, it will be aromatic with an induced magnetisation that opposes the external field inside the ring, whereas if it has 4n π-electrons, it will be antiaromatic with the opposite magnetisation. This rule reliably predicts the behaviour of small molecules, typically with circuits of less than about 22 π-electrons (n = 5). It is not clear whether aromaticity has a size limit and whether Hückel’s rule is valid in much larger macrocycles. Here, we present evidence for global aromaticity in a wide variety of porphyrin nanorings, with circuits of up to 162 π-electrons (n = 40; diameter 5 nm). We show that aromaticity can be controlled by changing the molecular structure, oxidation state and three-dimensional conformation. Whenever a global ring current is observed, its direction is correctly predicted by Hückel’s rule. The magnitude of the current is maximised when the average oxidation state of the porphyrin units is around 0.5–0.7, when the system starts to resemble a conductor with a partially filled valence band. Our results show that aromaticity can arise in large macrocycles, bridging the size gap between ring currents in molecular and mesoscopic rings.</p></div>

scholarly journals Upper ocean response to two collocated typhoons

2013 ◽  
Vol 10 (6) ◽  
pp. 2255-2292
Author(s):  
D. B. Baranowski ◽  
P. J. Flatau ◽  
S. Chen ◽  
P. G. Black
Keyword(s):  
Temperature Anomaly ◽  
Three Dimensional ◽  
Upper Ocean ◽  
Precursor State ◽  
Argo Float ◽  
Current Decay ◽  
High Repetition ◽  
Ocean Response ◽  
Oceanic Response ◽  
Upper Ocean Response

Abstract. The atmospheric wind stress forcing and the oceanic response are examined for the period between 15 September 2008 and 6 October 2008, during which two typhoons, Hagupit and Jangmi passed through the same region of the Western Pacific at Saffir–Simpson intensity categories one and three, respectively. A three-dimensional oceanic mixed layer model is compared against the remote sensing observations as well as high repetition Argo float data. Numerical model simulations suggested that magnitude of the cooling caused by the second typhoon, Jangmi, would have been significantly larger if the ocean had not already been influenced by the first typhoon, Hagupit. It is estimated that the temperature anomaly behind Jangmi would have been about 0.4 °C larger in both cold wake and left side of the track. The numerical simulations suggest that the magnitude and position of Jangmi's cold wake depends on the precursor state of the ocean as well as lag between typhoons. Based on sensitivity experiments we show that temperature anomaly difference between "single typhoon" and "two typhoons" as well as magnitude of the cooling strongly depends on the value of inertial current decay time parameter. Thus, the magnitude of the observed cooling depends also on the amount of kinetic energy in the upper ocean. This paper indicates that studies of ocean-atmosphere tropical cyclone interaction will benefit from denser, high repetition Argo float measurements.

Sign in / Sign up

Export Citation Format

Share Document