Evidence for the innermost inner core: Robust parameter search for radially varying anisotropy using the Neighbourhood Algorithm

2020 ◽  
Author(s):  
J. Stephenson ◽  
H Tkalčić ◽  
M. Sambridge
Keyword(s):  
Inner Core ◽  
Parameter Search ◽  
Robust Parameter ◽  
Neighbourhood Algorithm

An Electron Microscopic Study of an Avian Reovirus that Causes Arthritis

1971 ◽  
Vol 29 ◽  
pp. 254-255
Author(s):  
E, R. Walker ◽  
N. O. Olson ◽  
M. H. Friedman
Keyword(s):  
Electron Microscopy ◽  
Viral Genome ◽  
Inner Core ◽  
Avian Reovirus ◽  
Electron Microscopic ◽  
Outer Coat ◽  
Acid Type ◽  
Chicken Eggs ◽  
Icosahedral Particle ◽  
Mature Virus

An unidentified virus, responsible for an arthritic-like condition in chickens was studied by electron microscopy and other methods of viral investigation. It was characterized in chorio-allantoic membrane (CAM) lesions of embryonating chicken eggs and in tissue culture as to: 1) particle size; 2) structure; 3) mode of replication in the cell; and 4) nucleic acid type.The inoculated virus, coated and uncoated, is first seen in lysosomal-like inclusions near the nucleus; the virions appear to be uncoated in these electron dense inclusions (Figure 1), Although transfer of the viral genome from these inclusions is not observable, replicating virus and mature virus crystals are seen in the cytoplasm subsequent to the uncoating of the virions.The crystals are formed in association with a mass of fibrils 50 to 80 angstroms in diameter and a ribosome-studded structure that appears to be granular endoplasmic reticulum adapted to virus replication (Figure 2). The mature virion (Figure 3) is an icosahedral particle approximately 75 millimicrons in diameter. The inner core is 45 millimicrons, the outer coat 15 millimicrons, and the virion has no envelope.

Robust Parameter Adjustment

1988 ◽  
Author(s):  
James M. Krause ◽  
Pramod P. Khargonekar
Keyword(s):  
Parameter Adjustment ◽  
Robust Parameter

Preliminary Studies on Non-Reactive Flow Vortex Cooling

2019 ◽  
Vol 12 (3) ◽  
pp. 262-271
Author(s):  
T.N. Rajesh ◽  
T.J.S. Jothi ◽  
T. Jayachandran
Keyword(s):  
Combustion Chamber ◽  
Inner Core ◽  
Rocket Engine ◽  
Injection Pressure ◽  
Chamber Pressure ◽  
Reactive Flow ◽  
Stoichiometric Ratio ◽  
Gaseous Oxygen ◽  
Mixture Ratio ◽  
Vortex Combustion

Background: The impulse for the propulsion of a rocket engine is obtained from the combustion of propellant mixture inside the combustion chamber and as the plume exhausts through a convergent- divergent nozzle. At stoichiometric ratio, the temperature inside the combustion chamber can be as high as 3500K. Thus, effective cooling of the thrust chamber becomes an essential criterion while designing a rocket engine. Objective: A new cooling method of thrust chambers was introduced by Chiaverni, which is termed as Vortex Combustion Cold-Wall Chamber (VCCW). The patent works on cyclone separators and confined vortex flow mechanism for providing high propellant mixing with improved degree of turbulence inside the combustion chamber, providing the required notion for studies on VCCW. The flow inside a VCCW has a complex structure characterised by axial pressure losses, swirl velocities, centrifugal force, flow reversal and strong turbulence. In order to study the flow phenomenon, both the experimental and numerical investigations are carried out. Methods: In this study, non-reactive flow analysis was conducted with real propellants like gaseous oxygen and hydrogen. The test was conducted to analyse the influence of mixture ratio and injection pressure of the propellants on the chamber pressure in a vortex combustion chamber. A vortex combustor was designed in which the oxidiser injected tangentially at the aft end near the nozzle spiraled up to the top plate and formed an inner core inside the chamber. The fuel was injected radially from injectors provided near the top plate and the propellants were mixed in the inner core. This resulted in enhanced mixing and increased residence time for the fuel. More information on the flow behaviour has been obtained by numerical analysis in Fluent. The test also investigated the sensitivity of the tangential injection pressure on the chamber pressure development. Results: All the test cases showed an increase in chamber pressure with the mixture ratio and injection pressure of the propellants. The maximum chamber pressure was found to be 3.8 bar at PC1 and 2.7 bar at PC2 when oxidiser to fuel ratio was 6.87. There was a reduction in chamber pressure of 1.1 bar and 0.7 bar at PC1 and PC2, respectively, in both the cases when hydrogen was injected. A small variation in the pressure of the propellant injected tangentially made a pronounced effect on the chamber pressure and hence vortex combustion chamber was found to be very sensitive to the tangential injection pressure. Conclusion: VCCW mechanism has been to be found to be very effective for keeping the chamber surface within the permissible limit and also reducing the payload of the space vehicle.

Ups and Downs

2018 ◽  
Author(s):  
Roy Livermore
Keyword(s):  
Mantle Convection ◽  
Laboratory Experiments ◽  
Inner Core ◽  
Computer Modelling ◽  
Great Depth ◽  
New Horizons ◽  
The Core ◽  
The Earth ◽  
The World ◽  
The 1960S

Despite the dumbing-down of education in recent years, it would be unusual to find a ten-year-old who could not name the major continents on a map of the world. Yet how many adults have the faintest idea of the structures that exist within the Earth? Understandably, knowledge is limited by the fact that the Earth’s interior is less accessible than the surface of Pluto, mapped in 2016 by the NASA New Horizons spacecraft. Indeed, Pluto, 7.5 billion kilometres from Earth, was discovered six years earlier than the similar-sized inner core of our planet. Fortunately, modern seismic techniques enable us to image the mantle right down to the core, while laboratory experiments simulating the pressures and temperatures at great depth, combined with computer modelling of mantle convection, help identify its mineral and chemical composition. The results are providing the most rapid advances in our understanding of how this planet works since the great revolution of the 1960s.

scholarly journals Circulating bioactive sclerostin levels in an Austrian population-based cohort

2021 ◽  
Author(s):  
Katharina Kerschan-Schindl ◽  
Ursula Föger-Samwald ◽  
Andreas Gleiss ◽  
Stefan Kudlacek ◽  
Jacqueline Wallwitz ◽  
...  
Keyword(s):  
Serum Levels ◽  
Population Based ◽  
Negative Regulator ◽  
Total Serum ◽  
Mineral Density ◽  
Cross Sectional ◽  
Robust Parameter ◽  
Austrian Population ◽  
Different Levels

Summary Background Circulating serum sclerostin levels are supposed to give a good estimation of the levels of this negative regulator of bone mass within bone. Most studies evaluating total serum sclerostin found different levels in males compared to females and in older compared to younger subjects. Besides an ELISA detecting total sclerostin an ELISA determining bioactive sclerostin has been developed. The aim of this study was to investigate serum levels of bioactive sclerostin in an Austrian population-based cohort. Methods We conducted a cross-sectional observational study in 235 healthy subjects. Using the bioactive ELISA assay (Biomedica) bioactive sclerostin levels were evaluated. Results Serum levels of bioactive sclerostin were higher in men than in women (24%). The levels correlated positively with age (r = 0.47). A positive correlation could also be detected with body mass index and bone mineral density. Conclusion Using the ELISA detecting bioactive sclerostin our results are consistent with data in the literature obtained by different sclerostin assays. The determination of sclerostin concentrations in peripheral blood thus appears to be a robust parameter of bone metabolism.

Consensus in networks of uncertain robot manipulators without using neighbors’ velocity information

Robotica ◽  
2021 ◽  
pp. 1-17
Author(s):  
Seyed Mostafa Almodarresi ◽  
Marzieh Kamali ◽  
Farid Sheikholeslam
Keyword(s):  
Information Exchange ◽  
Lyapunov Functions ◽  
Robot Manipulators ◽  
Adaptive Methods ◽  
Convergence Time ◽  
Parameter Search ◽  
Velocity Information ◽  
Simulation Results ◽  
Uncertain Robot ◽  
Asymptotic Synchronization

Abstract In this paper, new distributed adaptive methods are proposed for solving both leaderless and leader–follower consensus problems in networks of uncertain robot manipulators, by estimating only the gravitational torque forces. Comparing with the existing adaptive methods, which require the estimation of the whole dynamics, presented methods reduce the excitation levels required for efficient parameter search, the convergence time, and the complexity of the regressor. Additionally, proposed schemes eliminate the need for velocity information exchange between the agents. Global asymptotic synchronization is shown by introducing new Lyapunov functions. Simulation results are provided for a network of 10 4-DOF robot manipulators.

scholarly journals Simple, green, ultrasound-assisted preparation of novel core–shell microcapsules from octyl methoxycinnamate and oligomeric proanthocyanidins for UV-stable sunscreen

RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 6374-6382
Author(s):  
Jie Song ◽  
Siqi Chen ◽  
Xu Zhao ◽  
Junbo Cheng ◽  
Yanli Ma ◽  
...  
Keyword(s):  
Inner Core ◽  
Outer Shell ◽  
Core Shell ◽  
Uv Resistance ◽  
Oligomeric Proanthocyanidins ◽  
Ultraviolet Absorbers ◽  
Ultrasound Assisted

With oligomeric proanthocyanidins (OPCs) as the outer shell and ultraviolet absorbers (OMC) as the inner core, OMC/OPCs composite microcapsules were prepared and characterized, and their UV resistance was studied.

scholarly journals Osmotic stress and vesiculation as key mechanisms controlling bacterial sensitivity and resistance to TiO2 nanoparticles

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Christophe Pagnout ◽  
Angelina Razafitianamaharavo ◽  
Bénédicte Sohm ◽  
Céline Caillet ◽  
Audrey Beaussart ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Osmotic Stress ◽  
Inner Core ◽  
Metal Oxide Nanoparticles ◽  
Membrane Vesicles ◽  
Outer Core ◽  
Membrane Composition ◽  
Cell Turgor ◽  
Bacterial Sensitivity ◽  
Membrane Components

AbstractToxicity mechanisms of metal oxide nanoparticles towards bacteria and underlying roles of membrane composition are still debated. Herein, the response of lipopolysaccharide-truncated Escherichia coli K12 mutants to TiO2 nanoparticles (TiO2NPs, exposure in dark) is addressed at the molecular, single cell, and population levels by transcriptomics, fluorescence assays, cell nanomechanics and electrohydrodynamics. We show that outer core-free lipopolysaccharides featuring intact inner core increase cell sensitivity to TiO2NPs. TiO2NPs operate as membrane strippers, which induce osmotic stress, inactivate cell osmoregulation and initiate lipid peroxidation, which ultimately leads to genesis of membrane vesicles. In itself, truncation of lipopolysaccharide inner core triggers membrane permeabilization/depolarization, lipid peroxidation and hypervesiculation. In turn, it favors the regulation of TiO2NP-mediated changes in cell Turgor stress and leads to efficient vesicle-facilitated release of damaged membrane components. Remarkably, vesicles further act as electrostatic baits for TiO2NPs, thereby mitigating TiO2NPs toxicity. Altogether, we highlight antagonistic lipopolysaccharide-dependent bacterial responses to nanoparticles and we show that the destabilized membrane can generate unexpected resistance phenotype.

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