scholarly journals Role of molecular species in pickup ion sputtering of the Martian atmosphere

Author(s):  
F. Leblanc
Author(s):  
Rojeet Shrestha ◽  
Shu-Ping Hui ◽  
Yusuke Miura ◽  
Akiko Yagi ◽  
Yuji Takahashi ◽  
...  

AbstractThe role of triglycerides carried in the triglyceride-rich lipoproteins (TRL) in the progression of atherosclerosis is uncertain. Identification of oxidized triglycerides and its possible association with atherosclerosis were largely ignored. Here we applied mass spectrometric approach to detect and identify triglyceride hydroperoxides (TGOOH) in human plasma and lipoproteins.EDTA plasma was collected from healthy human volunteers (n=9) after 14–16 h of fasting. Very low-density lipoprotein (VLDL)We identified 11 molecular species of TGOOH in either plasma or VLDL and IDL, of which TGOOH-18:1/18:2/16:0, TGOOH-18:1/18:1/16:0, TGOOH-16:0/18:2/16:0, TGOOH-18:1/18:1/18:1, and TGOOH-16:0/20:4/16:0 were most dominant. These TGOOH molecules are carried by TRL but not by LDL and HDL. Mean concentration of TGOOH in plasma, VLDL and IDL were, respectively, 56.1±25.6, 349.8±253.6 and 512.5±173.2 μmol/mol of triglycerides.This is the first report to identify several molecular species of oxidized triglycerides in TRL. Presence of oxidized triglyceride may contribute to the atherogenicity of TRL. Further work is needed to elucidate the association of the oxidized triglyceride in atherosclerosis.


2005 ◽  
Vol 45 (supplement) ◽  
pp. S94
Author(s):  
K. Matsumura ◽  
S. Matsunaga ◽  
N. Fusetani
Keyword(s):  

2003 ◽  
Vol 9 (4) ◽  
pp. 287-294 ◽  
Author(s):  
Detlef Schröder ◽  
Marija Semialjac ◽  
Helmut Schwarz

Author(s):  
M. V. Bell ◽  
J. R. Dick

The retina of larval herring (Clupea harengus L.) contains only cones, with rods recruited progressively from about eight weeks onwards. The molecular species composition of phospholipids from the eyes of herring of different ages was determined to find whether the appearance of di-docosahexaenoyl molecular species (di22:6n-3) of phospholipids, which are characteristic of rod outer segment membranes in higher vertebrates, coincided with the appearance of rods. In the eyes of larval herring (cone-only retina) di22:6n-3 molecular species comprised 25.9% of phosphatidylethanolamine (PE), 22.9% of phosphatidylserine (PS) and 4.2% of phosphatidylcholine (PC). In the eyes of adult herring (rod:cone ratio of about 20:1) the proportion of di22:6n-3 molecular species had increased to 49.5%, 39.0% and 16.8% in PE, PS and PC, respectively. Juvenile herring had intermediate values of di22:6n-3 phospholipids. The results confirm the hypothesis that the amounts of di22:6n-3 molecular species of phospholipids in retina increase during development as rods appear, and also show that cones contain smaller amounts of these unique lipids. Three other molecular species containing docosahexaenoic acid, 16:0/22:6n-3, 18:1/22:6n-3 and 18:0/22:6n-3 were also major components of eye phospholipids, emphasizing the important role of 22:6n-3 in vision.


2014 ◽  
Vol 118 (2) ◽  
pp. 1071-1080 ◽  
Author(s):  
Ali Traboulsi ◽  
Johan Vandenborre ◽  
Guillaume Blain ◽  
Bernard Humbert ◽  
Jacques Barbet ◽  
...  

2010 ◽  
Vol 9 (4) ◽  
pp. 193-200 ◽  
Author(s):  
John Parnell ◽  
Adrian J. Boyce ◽  
Nigel J.F. Blamey

AbstractIf life occurs elsewhere in the Solar System, there is a strong likelihood that it occurs in a deep biosphere beneath the planetary surface. The evidence for methane in the martian atmosphere has drawn attention to the possible role of serpentinites in fuelling a deep biosphere through the generation of hydrogen and/or methane. Serpentinites represent a good target for the search for biosignatures in a range of reaction products. Isotopic measurements in each of methane, sulphide and carbonate in serpentinites can help determine evidence of biological activity. We show that ancient terrestrial serpentinites retain methane that could be subject to the measurement of carbon and hydrogen isotopes. There is, therefore, potential to sample serpentinites on Mars and test for evidence of life in the deep geological record of Mars.


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