High-resolution Indian Ocean simulations—Recent advances and issues from OFES

2008 ◽  
pp. 199-212 ◽  
Author(s):  
Yukio Masumoto ◽  
Yushi Morioka ◽  
Hideharu Sasaki
Keyword(s):  
High Resolution ◽  
Indian Ocean ◽  
Recent Advances

Nucleosome dynamics

2006 ◽  
Vol 73 ◽  
pp. 109-119 ◽  
Author(s):  
Chris Stockdale ◽  
Michael Bruno ◽  
Helder Ferreira ◽  
Elisa Garcia-Wilson ◽  
Nicola Wiechens ◽  
...  
Keyword(s):  
High Resolution ◽  
Chromatin Structure ◽  
Current Knowledge ◽  
Dynamic Properties ◽  
Structure And Dynamics ◽  
Nucleosome Dynamics ◽  
Sharp Focus ◽  
Recent Advances ◽  
Insight Into ◽  
Chromatin Structure And Dynamics

In the 30 years since the discovery of the nucleosome, our picture of it has come into sharp focus. The recent high-resolution structures have provided a wealth of insight into the function of the nucleosome, but they are inherently static. Our current knowledge of how nucleosomes can be reconfigured dynamically is at a much earlier stage. Here, recent advances in the understanding of chromatin structure and dynamics are highlighted. The ways in which different modes of nucleosome reconfiguration are likely to influence each other are discussed, and some of the factors likely to regulate the dynamic properties of nucleosomes are considered.

scholarly journals Recent advances in understanding and managing chronic constipation

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1640 ◽  
Author(s):  
David O. Prichard ◽  
Adil E. Bharucha
Keyword(s):  
High Resolution ◽  
The United States ◽  
Empiric Therapy ◽  
Therapeutic Agents ◽  
Western Society ◽  
Molecular Physiology ◽  
High Resolution Manometry ◽  
Recent Advances ◽  
Bile Acid Transporters ◽  
Life Threatening

Constipation, a condition characterized by heterogeneous symptoms, is common in Western society. It is associated with reduced physical health, mental health, and social functioning. Because constipation is rarely due to a life-threatening disease (for example, colon cancer), current guidelines recommend empiric therapy. Limited surveys suggest that fewer than half of treated individuals are satisfied with treatment, perhaps because the efficacy of drugs is limited, they are associated with undesirable side effects, or they may not target the underlying pathophysiology. For example, although a substantial proportion of constipated patients have a defecatory disorder that is more appropriately treated with pelvic floor biofeedback therapy than with laxatives, virtually no pharmacological trials formally assessed for anorectal dysfunction. Recent advances in investigational tools have improved our understanding of the physiology and pathophysiology of colonic and defecatory functions. In particular, colonic and anorectal high-resolution manometry are now available. High-resolution anorectal manometry, which is increasingly used in clinical practice, at least in the United States, provides a refined assessment of anorectal pressures and may uncover structural abnormalities. Advances in our understanding of colonic molecular physiology have led to the development of new therapeutic agents (such as secretagogues, pro-kinetics, inhibitors of bile acid transporters and ion exchangers). However, because clinical trials compare these newer agents with placebo, their efficacy relative to traditional laxatives is unknown. This article reviews these physiologic, diagnostic, and therapeutic advances and focuses particularly on newer therapeutic agents.

High-Resolution Digital Elevation and Bathymetry Model for Tsunami Run-Up and Inundation Simulation in Penang

2019 ◽  
Vol 13 (05n06) ◽  
pp. 1941001
Author(s):  
Su Yean Teh ◽  
Hock Lye Koh ◽  
Yong Hui Lim
Keyword(s):  
High Resolution ◽  
Indian Ocean ◽  
Sea Level ◽  
Interpolation Method ◽  
Topographic Maps ◽  
Seamless Integration ◽  
Topographic Data ◽  
Digital Elevation ◽  
Run Up ◽  
Tsunami Run Up

Many beaches in Penang island were severely inundated by the 26 December 2004 Indian Ocean mega tsunami with 57 deaths recorded. It is anticipated that the next big tsunami will cause even more damages to beaches in Penang. Hence, developing community resilience against the risks of the next tsunami is essential. Resilience entails many interlinked components, beginning with a good understanding of the inundation scenarios critical to community evacuation and resilience preparation. Inundation scenarios are developed from tsunami simulations involving all three phases of tsunami generation, propagation and run-up. Accurate and high-resolution bathymetric–topographic maps are essential for simulations of tsunami wave inundation along beaches. Bathymetric maps contain information on the depths of landforms below sea level while topographic maps reveal the elevation of landforms above sea level. Bathymetric and topographic datasets for Malaysia are, however, currently not integrated and are available separately and in different formats, not suitable for inundation simulations. Bathymetric data are controlled by the National Hydrographic Centre (NHC) of the Royal Malaysian Navy while topographic data are serviced by the Department of Survey and Mapping Malaysia (JUPEM). It is highly desirable to have seamless integration of high-resolution bathymetric and topographic data for tsunami simulations and for other scientific studies. In this paper, we develop a robust method for integrating the NHC bathymetric and JUPEM topographic data into a regularly-spaced grid system essential for tsunami simulation. A primary objective of this paper is to develop the best Digital Elevation and Bathymetry Model (DEBM) for Penang based upon the most suitable and accurate interpolation method for integrating bathymetric and topographic data with minimal interpolation errors. We analyze four commonly used interpolation methods for generating gridded topographic and bathymetric surfaces, namely (i) Kriging, (ii) Multiquadric (MQ), (iii) Thin Plate Spline (TPS) and (iv) Inverse Distance to Power (IDP). The study illustrated that the Kriging interpolation method produces an integrated bathymetric and topographic surface that best approximates the admiralty nautical chart of Penang essential for tsunami run-up and inundation simulations. Tsunami inundation scenarios critical to risk analysis and mitigation could then be developed using this DEBM for various earthquake scenarios, as presented in this paper for the 2004 Indian Ocean Tsunami.

scholarly journals A high-resolution, absolute-dated deglacial speleothem record of Indian Ocean climate from Socotra Island, Yemen

2007 ◽  
Vol 259 (3-4) ◽  
pp. 442-456 ◽  
Author(s):  
Jeremy D. Shakun ◽  
Stephen J. Burns ◽  
Dominik Fleitmann ◽  
Jan Kramers ◽  
Albert Matter ◽  
...  
Keyword(s):  
High Resolution ◽  
Indian Ocean ◽  
Ocean Climate ◽  
Socotra Island

scholarly journals ASIRI: An Ocean–Atmosphere Initiative for Bay of Bengal

2016 ◽  
Vol 97 (10) ◽  
pp. 1859-1884 ◽  
Author(s):  
Hemantha W. Wijesekera ◽  
Emily Shroyer ◽  
Amit Tandon ◽  
M. Ravichandran ◽  
Debasis Sengupta ◽  
...  
Keyword(s):  
Boundary Layer ◽  
High Resolution ◽  
Indian Ocean ◽  
Bay Of Bengal ◽  
Regional Scale ◽  
Ocean Dynamics ◽  
Coastal Current ◽  
Northeast Monsoon ◽  
Low Salinity ◽  
Salinity Water

Abstract Air–Sea Interactions in the Northern Indian Ocean (ASIRI) is an international research effort (2013–17) aimed at understanding and quantifying coupled atmosphere–ocean dynamics of the Bay of Bengal (BoB) with relevance to Indian Ocean monsoons. Working collaboratively, more than 20 research institutions are acquiring field observations coupled with operational and high-resolution models to address scientific issues that have stymied the monsoon predictability. ASIRI combines new and mature observational technologies to resolve submesoscale to regional-scale currents and hydrophysical fields. These data reveal BoB’s sharp frontal features, submesoscale variability, low-salinity lenses and filaments, and shallow mixed layers, with relatively weak turbulent mixing. Observed physical features include energetic high-frequency internal waves in the southern BoB, energetic mesoscale and submesoscale features including an intrathermocline eddy in the central BoB, and a high-resolution view of the exchange along the periphery of Sri Lanka, which includes the 100-km-wide East India Coastal Current (EICC) carrying low-salinity water out of the BoB and an adjacent, broad northward flow (∼300 km wide) that carries high-salinity water into BoB during the northeast monsoon. Atmospheric boundary layer (ABL) observations during the decaying phase of the Madden–Julian oscillation (MJO) permit the study of multiscale atmospheric processes associated with non-MJO phenomena and their impacts on the marine boundary layer. Underway analyses that integrate observations and numerical simulations shed light on how air–sea interactions control the ABL and upper-ocean processes.

High-resolution dipolar n.m.r. spectra in solids

1981 ◽  
Vol 299 (1452) ◽  
pp. 547-563 ◽  
Keyword(s):  
Molecular Structure ◽  
Solid State ◽  
High Resolution ◽  
Single Crystal ◽  
Two Dimensional ◽  
Dipolar Interactions ◽  
Recent Advances ◽  
Powder Samples ◽  
Successful Observation

Recent advances in solid state n.m.r. spectroscopy permit obervation of high-resolution dipolar spectra, and thus renewed consideration can be given to solid state n.m.r. as a tool for determining molecular structure. This is illustrated with 13 C and 14 N single-crystal spectra obtained with both one- and two-dimensional n.m.r. techniques. The successful observation of these spectra is due to the fact that many dipolar interactions are inhomogeneous, and for this reason it is also possible to obtain high-resolution dipolar spectra from powder samples. Methods that accomplish this goal are described and illustrated with 13 C - 1 H dipolar spectra.

P-Cable High Resolution 3D Seismic - Case Study and Recent Advances

2015 ◽  
Author(s):  
Frode N. Eriksen* ◽  
C. Berndt ◽  
J. Karstens ◽  
G.J. Crutchley
Keyword(s):  
High Resolution ◽  
3D Seismic ◽  
Recent Advances
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