New Concepts in Immunology Relevant to Idiosyncratic Drug Reactions:  The “Danger Hypothesis” and Innate Immune System

Jack P. Uetrecht

doi:10.1021/tx980249i

New Concepts in Immunology Relevant to Idiosyncratic Drug Reactions: The “Danger Hypothesis” and Innate Immune System

Chemical Research in Toxicology ◽

10.1021/tx980249i ◽

1999 ◽

Vol 12 (5) ◽

pp. 387-395 ◽

Cited By ~ 220

Author(s):

Jack P. Uetrecht

Keyword(s):

Immune System ◽

Innate Immune System ◽

Innate Immune ◽

Idiosyncratic Drug Reactions ◽

Drug Reactions ◽

New Concepts

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The activation of the hepatic innate immune system by siRNA is controlled by chemical modifications and may involve endosomal Toll-like receptors

Zeitschrift für Gastroenterologie ◽

10.1055/s-0029-1246501 ◽

2010 ◽

Vol 48 (01) ◽

Author(s):

R Bröring ◽

M John ◽

K Kleinehr ◽

JP Sowa ◽

A Bucchi ◽

...

Keyword(s):

Immune System ◽

Innate Immune System ◽

Innate Immune ◽

Toll Like Receptors ◽

Chemical Modifications

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Faculty Opinions recommendation of Arthritis critically dependent on innate immune system players.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004826.55656 ◽

2002 ◽

Author(s):

Andy Chan

Keyword(s):

Immune System ◽

Innate Immune System ◽

Innate Immune

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Faculty Opinions recommendation of Arthritis critically dependent on innate immune system players.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004826.77155 ◽

2002 ◽

Author(s):

Andrew Cope

Keyword(s):

Immune System ◽

Innate Immune System ◽

Innate Immune

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Faculty Opinions recommendation of The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1026778.325390 ◽

2005 ◽

Author(s):

Lewis Lanier

Keyword(s):

Dna Damage ◽

Immune System ◽

Innate Immune System ◽

Innate Immune ◽

Nkg2d Receptor

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Faculty Opinions recommendation of The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1026778.325389 ◽

2005 ◽

Author(s):

Lucio Comai

Keyword(s):

Dna Damage ◽

Immune System ◽

Innate Immune System ◽

Innate Immune ◽

Nkg2d Receptor

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Faculty Opinions recommendation of AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1032842.374922 ◽

2006 ◽

Author(s):

Kenneth Vernick

Keyword(s):

Immune System ◽

Anopheles Gambiae ◽

Innate Immune System ◽

Innate Immune ◽

Immunoglobulin Domain

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Faculty Opinions recommendation of A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1059744.513791 ◽

2007 ◽

Author(s):

Etienne Joly

Keyword(s):

Immune System ◽

Innate Immune System ◽

Critical Role ◽

Innate Immune

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Faculty Opinions recommendation of Cancer immunoediting by the innate immune system in the absence of adaptive immunity.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717960239.793463319 ◽

2012 ◽

Author(s):

Surender Kharbanda ◽

Abhishek Garg

Keyword(s):

Immune System ◽

Adaptive Immunity ◽

Innate Immune System ◽

Innate Immune ◽

Cancer Immunoediting

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Faculty Opinions recommendation of Multi-receptor detection of individual bacterial products by the innate immune system.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727578490.793545326 ◽

2018 ◽

Author(s):

Sekhar Reddy

Keyword(s):

Immune System ◽

Innate Immune System ◽

Innate Immune ◽

Bacterial Products

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Understanding the Effects of Cytotoxic Chemotherapeutics on the Innate Immune System

10.21236/ada570818 ◽

2012 ◽

Author(s):

Elizabeth S. Nakasone

Keyword(s):

Immune System ◽

Innate Immune System ◽

Innate Immune

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