Prediction of Aryl Hydrocarbon Receptor-Mediated Enzyme Induction of Drugs and Chemicals by mRNA Quantification

Roland Frötschl; Lubomir Chichmanov; Ullrich Kleeberg; Alfred G. Hildebrandt; Ivar Roots; Jürgen Brockmöller

doi:10.1021/tx980164h

Prediction of Aryl Hydrocarbon Receptor-Mediated Enzyme Induction of Drugs and Chemicals by mRNA Quantification

Chemical Research in Toxicology ◽

10.1021/tx980164h ◽

1998 ◽

Vol 11 (12) ◽

pp. 1447-1452 ◽

Cited By ~ 11

Author(s):

Roland Frötschl ◽

Lubomir Chichmanov ◽

Ullrich Kleeberg ◽

Alfred G. Hildebrandt ◽

Ivar Roots ◽

...

Keyword(s):

Aryl Hydrocarbon Receptor ◽

Enzyme Induction ◽

Mrna Quantification ◽

Aryl Hydrocarbon

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Enzyme induction and histopathology elucidate aryl hydrocarbon receptor-mediated versus non-aryl hydrocarbon receptor-mediated effects of Aroclor 1268 in American mink (Neovison vison)

Environmental Toxicology and Chemistry ◽

10.1002/etc.3203 ◽

2016 ◽

Vol 35 (3) ◽

pp. 619-634 ◽

Cited By ~ 3

Author(s):

William R. Folland ◽

John L. Newsted ◽

Scott D. Fitzgerald ◽

Phyllis C. Fuchsman ◽

Patrick W. Bradley ◽

...

Keyword(s):

Aryl Hydrocarbon Receptor ◽

Enzyme Induction ◽

American Mink ◽

Neovison Vison ◽

Aryl Hydrocarbon ◽

Mediated Effects ◽

Aroclor 1268

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Human Response to Dioxin: Aryl Hydrocarbon Receptor (AhR) Molecular Structure, Function, and Dose-Response Data for Enzyme Induction Indicate an Impaired Human AhR

Journal of Toxicology and Environmental Health Part B ◽

10.1080/15287390500196487 ◽

2006 ◽

Vol 9 (2) ◽

pp. 147-171 ◽

Cited By ~ 61

Author(s):

Kevin T. Connor ◽

Lesa L. Aylward

Keyword(s):

Molecular Structure ◽

Structure Function ◽

Aryl Hydrocarbon Receptor ◽

Enzyme Induction ◽

Dose Response ◽

Human Response ◽

Response Data ◽

Aryl Hydrocarbon

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Germline aryl hydrocarbon receptor interacting protein (AIP) gene mutations in patients with apparently sporadic pituitary macroadenomas (PMA): initial results

Endocrine Abstracts ◽

10.1530/endoabs.35.p833 ◽

2014 ◽

Author(s):

Anna Skalniak ◽

Malgorzata Trofimiuk-Muldner ◽

Jakub Pietkowski ◽

Grzegorz Sokolowski ◽

Alicja Hubalewska-Dydejczyk

Keyword(s):

Aryl Hydrocarbon Receptor ◽

Gene Mutations ◽

Interacting Protein ◽

Aryl Hydrocarbon ◽

Aip Gene ◽

Initial Results ◽

Pituitary Macroadenomas

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Functional analysis of aryl hydrocarbon receptor (AHR) polymorphisms in pituitary adenomas (PAs) in the presence of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)

Endocrine Abstracts ◽

10.1530/endoabs.56.p777 ◽

2018 ◽

Author(s):

Jessica Debattista ◽

Robert Formosa ◽

Josanne Vassallo

Keyword(s):

Functional Analysis ◽

Aryl Hydrocarbon Receptor ◽

Pituitary Adenomas ◽

Aryl Hydrocarbon ◽

Tetrachlorodibenzo P Dioxin

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Faculty Opinions recommendation of Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104468.568151 ◽

2008 ◽

Author(s):

Mark Boothby

Keyword(s):

Cell Differentiation ◽

Aryl Hydrocarbon Receptor ◽

Aryl Hydrocarbon

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Faculty Opinions recommendation of The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1108250.564270 ◽

2008 ◽

Author(s):

Stefan Kaufmann

Keyword(s):

Aryl Hydrocarbon Receptor ◽

Th17 Cell ◽

Environmental Toxins ◽

Aryl Hydrocarbon

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Faculty Opinions recommendation of Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1139100.618707 ◽

2009 ◽

Author(s):

Mark Hogarth

Keyword(s):

T Cells ◽

Aryl Hydrocarbon Receptor ◽

Culture Medium ◽

Aryl Hydrocarbon

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Faculty Opinions recommendation of Expression of aryl hydrocarbon receptor (AHR) and AHR-interacting protein in pituitary adenomas: pathological and clinical implications.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1168265.630419 ◽

2009 ◽

Author(s):

Niki Karavitaki ◽

Theingi Aung

Keyword(s):

Aryl Hydrocarbon Receptor ◽

Pituitary Adenomas ◽

Clinical Implications ◽

Interacting Protein ◽

Aryl Hydrocarbon

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Faculty Opinions recommendation of Mice with inactivation of aryl hydrocarbon receptor-interacting protein (Aip) display complete penetrance of pituitary adenomas with aberrant ARNT expression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5418956.5374054 ◽

2010 ◽

Author(s):

Ernesto De Menis ◽

Paola Sartorato

Keyword(s):

Aryl Hydrocarbon Receptor ◽

Pituitary Adenomas ◽

Interacting Protein ◽

Aryl Hydrocarbon ◽

Complete Penetrance

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Faculty Opinions recommendation of Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4942963.4875063 ◽

2010 ◽

Author(s):

Rachel R Caspi ◽

Ru Zhou

Keyword(s):

T Cells ◽

T Cell ◽

Regulatory T Cells ◽

Aryl Hydrocarbon Receptor ◽

Regulatory T Cell ◽

Human Type ◽

Aryl Hydrocarbon

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