Role of Quinoids in Estrogen Carcinogenesis

1998 ◽  
Vol 11 (10) ◽  
pp. 1113-1127 ◽  
Author(s):  
Judy L. Bolton ◽  
Emily Pisha ◽  
Fagen Zhang ◽  
Shengxiang Qiu
Keyword(s):  
Estrogen Carcinogenesis

scholarly journals Estrogen carcinogenesis in the hamster kidney: role of cytotoxicity and cell proliferation.

1993 ◽  
Vol 101 (suppl 5) ◽  
pp. 259-264 ◽  
Author(s):  
J J Li ◽  
A Gonzalez ◽  
S Banerjee ◽  
S K Banerjee ◽  
S A Li
Keyword(s):  
Cell Proliferation ◽  
Estrogen Carcinogenesis

scholarly journals Endogenous estrogens—breast cancer and chemoprevention

2021 ◽  
Author(s):  
Beata Starek-Świechowicz ◽  
Bogusława Budziszewska ◽  
Andrzej Starek
Keyword(s):  
Breast Cancer ◽  
Estrogen Metabolism ◽  
Oxygen Species ◽  
Breast Malignancy ◽  
Proliferation And Differentiation ◽  
17Β Estradiol ◽  
Estrogen Carcinogenesis ◽  
Breast Tissues ◽  
Epigenetic Processes

AbstractBreast cancer is the most common female malignancy and the second leading cause of cancer related deaths. It is estimated that about 40% of all cancer in women is hormonally mediated. Both estrogens and androgens play critical roles in the initiation and development of breast cancer. Estrogens influence normal physiological growth, proliferation, and differentiation of breast tissues, as well as the development and progression of breast malignancy. Breast cancer is caused by numerous endo- and exogenous risk factors. The paper presents estrogen metabolism, in particular 17β-estradiol and related hormones. The mechanisms of estrogen carcinogenesis include the participation of estrogen receptors, the genotoxic effect of the estrogen metabolites, and epigenetic processes that are also presented. The role of reactive oxygen species in breast cancer has been described. It called attention to a role of numerous signaling pathways in neoplastic transformation. Chemoprotective agents, besides other phytoestrogens, classical antioxidants, synthetic compounds, and their mechanisms of action have been shown.

scholarly journals Estrogen Carcinogenesis in the Hamster Kidney: Role of Cytotoxicity and Cell Proliferation

1993 ◽  
Vol 101 ◽  
pp. 259 ◽  
Author(s):  
Jonathan J. Li ◽  
Alfonso Gonzalez ◽  
Snigdha Banerjee ◽  
Sushanta K. Banerjee ◽  
Sara Antonia Li
Keyword(s):  
Cell Proliferation ◽  
Estrogen Carcinogenesis

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management

The power of norms to sway fused group members

2018 ◽  
Vol 41 ◽  
Author(s):  
Winnifred R. Louis ◽  
Craig McGarty ◽  
Emma F. Thomas ◽  
Catherine E. Amiot ◽  
Fathali M. Moghaddam
Keyword(s):  
Evolutionary Anthropology ◽  
Normative Systems ◽  
Violent Extremism ◽  
Identity Fusion ◽  
Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

Elaborating the role of reflection and individual differences in the study of folk-economic beliefs

2018 ◽  
Vol 41 ◽  
Author(s):  
Kevin Arceneaux
Keyword(s):  
Decision Making ◽  
Individual Differences ◽  
Cognitive Processes ◽  
Evolutionary History ◽  
Behavioral Responses ◽  
History Of ◽  
Economic Beliefs

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.

The role of affect in feelings of obligation

2020 ◽  
Vol 43 ◽  
Author(s):  
Stefen Beeler-Duden ◽  
Meltem Yucel ◽  
Amrisha Vaish
Keyword(s):  
Positive Emotions ◽  
The Creation ◽  
Sense Of Obligation

Abstract Tomasello offers a compelling account of the emergence of humans’ sense of obligation. We suggest that more needs to be said about the role of affect in the creation of obligations. We also argue that positive emotions such as gratitude evolved to encourage individuals to fulfill cooperative obligations without the negative quality that Tomasello proposes is inherent in obligations.

Refining our understanding of the “elephant in the room”

2020 ◽  
Vol 43 ◽  
Author(s):  
Andrew Whiten
Keyword(s):  
Social Cognition ◽  
Cultural Evolution ◽  
Cognitive Abilities ◽  
Critical Factors ◽  
Technological Culture

Abstract The authors do the field of cultural evolution a service by exploring the role of non-social cognition in human cumulative technological culture, truly neglected in comparison with socio-cognitive abilities frequently assumed to be the primary drivers. Some specifics of their delineation of the critical factors are problematic, however. I highlight recent chimpanzee–human comparative findings that should help refine such analyses.

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