Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry

Joanna Zheng; Li Ma; Baomin Xin; Timothy Olah; W. Griffith Humphreys; Mingshe Zhu

doi:10.1021/tx600277y

Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry

Chemical Research in Toxicology ◽

10.1021/tx600277y ◽

2007 ◽

Vol 20 (5) ◽

pp. 757-766 ◽

Cited By ~ 86

Author(s):

Joanna Zheng ◽

Li Ma ◽

Baomin Xin ◽

Timothy Olah ◽

W. Griffith Humphreys ◽

...

Keyword(s):

Mass Spectrometry ◽

Ion Trap ◽

Reactive Metabolites ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Screening And Identification

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Chapter 3 Applications of Quadrupole-Linear Ion Trap Mass Spectrometry to the Analysis of Reactive Metabolites in Drug Discovery and Development

Advances in Molecular Toxicology ◽

10.1016/s1872-0854(09)00003-4 ◽

2009 ◽

pp. 59-98 ◽

Cited By ~ 1

Author(s):

Mingshe Zhu ◽

Bo Wen

Keyword(s):

Mass Spectrometry ◽

Drug Discovery ◽

Ion Trap ◽

Reactive Metabolites ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Drug Discovery And Development ◽

Quadrupole Linear Ion Trap

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High-Throughput Screening and Characterization of Reactive Metabolites Using Polarity Switching of Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometry

Analytical Chemistry ◽

10.1021/ac702232r ◽

2008 ◽

Vol 80 (5) ◽

pp. 1788-1799 ◽

Cited By ~ 78

Author(s):

Bo Wen ◽

Li Ma ◽

Sidney D. Nelson ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometry ◽

High Throughput Screening ◽

Ion Trap ◽

Reactive Metabolites ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Polarity Switching ◽

Quadrupole Linear Ion Trap

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Liquid chromatography quadrupole linear ion trap mass spectrometry for multiclass screening and identification of lipophilic marine biotoxins in bivalve mollusks

Journal of Chromatography A ◽

10.1016/j.chroma.2014.06.105 ◽

2014 ◽

Vol 1358 ◽

pp. 172-180 ◽

Cited By ~ 22

Author(s):

Haiyan Wu ◽

Mengmeng Guo ◽

Zhijun Tan ◽

Haiyan Cheng ◽

Zhaoxin Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Bivalve Mollusks ◽

Marine Biotoxins ◽

Screening And Identification ◽

Quadrupole Linear Ion Trap

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Rapid Screening of Glutathione-Trapped Reactive Metabolites by Linear Ion Trap Mass Spectrometry with Isotope Pattern-Dependent Scanning and Postacquisition Data Mining

Chemical Research in Toxicology ◽

10.1021/tx8001115 ◽

2008 ◽

Vol 21 (7) ◽

pp. 1477-1483 ◽

Cited By ~ 47

Author(s):

Li Ma ◽

Bo Wen ◽

Qian Ruan ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometry ◽

Data Mining ◽

Ion Trap ◽

Rapid Screening ◽

Reactive Metabolites ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Isotope Pattern

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Screening and identification of steroidal saponins from Anemarrhena asphodeloides employing UPLC tandem triple quadrupole linear ion trap mass spectrometry

Steroids ◽

10.1016/j.steroids.2017.06.011 ◽

2017 ◽

Vol 125 ◽

pp. 67-80 ◽

Cited By ~ 6

Author(s):

Yong-Gang Xia ◽

Xin-Dong Guo ◽

Jun Liang ◽

Bing-You Yang ◽

Hai-Xue Kuang

Keyword(s):

Mass Spectrometry ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Steroidal Saponins ◽

Screening And Identification ◽

Quadrupole Linear Ion Trap ◽

Anemarrhena Asphodeloides

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Screening and identification of potential active components in crudeFructus Corniusing solid-phase extraction and LC–LTQ-linear ion trap mass spectrometry

Pharmaceutical Biology ◽

10.3109/13880209.2011.599036 ◽

2011 ◽

Vol 50 (3) ◽

pp. 278-283 ◽

Cited By ~ 8

Author(s):

Gang Cao ◽

Chengrong Zhang ◽

Yun Zhang ◽

Xiaodong Cong ◽

Hao Cai ◽

...

Keyword(s):

Mass Spectrometry ◽

Solid Phase Extraction ◽

Ion Trap ◽

Solid Phase ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Phase Extraction ◽

Active Components ◽

Screening And Identification

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Simultaneous qualitative and quantitative determination of seven anticoagulant rodenticides in whole blood and urine samples using on-line solid phase extraction with liquid chromatography-linear ion trap mass spectrometry

Chinese Journal of Chromatography ◽

10.3724/sp.j.1123.2015.03010 ◽

2015 ◽

Vol 33 (7) ◽

pp. 691

Author(s):

Kejian HUANG ◽

Minping LU ◽

Zhe ZHOU ◽

Cuiwu LIN ◽

Ning YANG ◽

...

Keyword(s):

Mass Spectrometry ◽

Ion Trap ◽

Solid Phase ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Phase Extraction ◽

Qualitative And Quantitative ◽

On Line ◽

Blood And Urine Samples

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Rapid Screening of Doping Agents in Human Urine by Vacuum MALDI-Linear Ion Trap Mass Spectrometry

Analytical Chemistry ◽

10.1021/ac701878j ◽

2007 ◽

Vol 79 (21) ◽

pp. 8420-8420

Author(s):

H. Kosanam ◽

P. K. Sai Prakash ◽

C. R. Yates ◽

D. D. Miller ◽

S. Ramagiri

Keyword(s):

Mass Spectrometry ◽

Human Urine ◽

Ion Trap ◽

Rapid Screening ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap

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Differentiation of 1-O-alk-1′-enyl-2-acyl and 1-O-alkyl-2-acyl Glycerophospholipids by Multiple-Stage Linear Ion-Trap Mass Spectrometry with Electrospray Ionization

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2007.08.019 ◽

2007 ◽

Vol 18 (11) ◽

pp. 2065-2073 ◽

Cited By ~ 48

Author(s):

Fong-Fu Hsu ◽

John Turk

Keyword(s):

Mass Spectrometry ◽

Electrospray Ionization ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap

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Hybrid triple quadrupole-linear ion trap mass spectrometry in fragmentation mechanism studies: application to structure elucidation of buspirone and one of its metabolites

Journal of Mass Spectrometry ◽

10.1002/jms.876 ◽

2005 ◽

Vol 40 (8) ◽

pp. 1017-1029 ◽

Cited By ~ 24

Author(s):

Mei-Yi Zhang ◽

Nadia Pace ◽

Edward H. Kerns ◽

Teresa Kleintop ◽

Natasha Kagan ◽

...

Keyword(s):

Mass Spectrometry ◽

Structure Elucidation ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Fragmentation Mechanism ◽

Quadrupole Linear Ion Trap

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