scholarly journals Does Dietary Copper Supplementation Enhance or Diminish PCB126 Toxicity in the Rodent Liver?

2013 ◽  
Vol 26 (5) ◽  
pp. 634-644 ◽  
Author(s):  
Ian K. Lai ◽  
William D. Klaren ◽  
Miao Li ◽  
Brian Wels ◽  
Donald L. Simmons ◽  
...  
Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2246
Author(s):  
Mariangela Rondanelli ◽  
Milena Anna Faliva ◽  
Vittoria Infantino ◽  
Clara Gasparri ◽  
Giancarlo Iannello ◽  
...  

While in vitro and animal studies of osteoblastic and osteoclastic activity as well as bone resistance for copper are numerous, and the results encouraging in terms of regulation, human studies are scarce. The aim of this narrative review was to investigate the correlation of blood copper, daily copper intake, and copper supplementation with bone mineral density. This review included 10 eligible studies: five studies concerned copper blood levels, one study concerned daily copper intake, and four studies concerned copper supplementation. Blood copper levels did not show statistically significant differences in four of the studies analyzed, while only one study showed differences between osteoporotic and healthy women, although only with women between 45 and 59 years of age and not between 60 and 80 years of age. The dietary copper intake among women with or without osteoporosis did not show any differences. Only one study with a small sample of subjects carried out these assessments; therefore, it is a topic that the literature must deepen with further studies. The two studies that analyzed the integration of copper (2.5–3 mg/day) only showed good results in terms of slowing down bone mineral loss and reducing resorption markers, confirming the effectiveness of copper supplementation on bone metabolism.


Author(s):  
H. Kaya ◽  
A. Kaya ◽  
M. Macit ◽  
S. Çelebi ◽  
Ö. Kaynar

The present study envisaged the effects of different levels of dietary copper supplementation on performance, egg quality parameters, serum and yolk cholesterol and triglyceride levels, and yolk fatty acid profile in laying hens. Total 96 Lohman laying hens (38 weeks old) were randomly divided into four groups (n=24 each). Experimental diets were prepared by adding copper (0, 200, 250 or 300 mg/kg) to basal diet and feeding was lasted 12 weeks. Dietary copper supplementation decreased egg weight and feed intake but did not affect other performance parameters compared to the control diet. Shape index, shell weight, shell thickness, yolk color, yolk index, albumen index, and haugh unit were not influenced by dietary copper supplementation, whereas shell strength increased due to the inclusion of copper in the basal diet. Copper supplementation did not affect the fatty acid profile of the egg yolk. The yolk cholesterol ratio decreased by 7.22% in the presence of 250 mg/kg copper supplementation compared to control diet. Therefore, high levels of dietary copper supplementation in the diet of laying hens can be beneficial for improving shell strength and reducing the cholesterol content of the yolk.


2005 ◽  
Vol 49 (5) ◽  
pp. 283-288 ◽  
Author(s):  
C.M. Galhardi ◽  
Y.S. Diniz ◽  
H.G. Rodrigues ◽  
L.A. Faine ◽  
R.C. Burneiko ◽  
...  

1997 ◽  
Vol 134 (1-2) ◽  
pp. 330 ◽  
Author(s):  
D.J. Lamb ◽  
G.L. Reeves ◽  
A. Taylor ◽  
G.A.A. Ferns

Author(s):  
Seidu Adams ◽  
Meng Hongjiao ◽  
Dongsheng Che ◽  
Jiang Hailong ◽  
Han Rui ◽  
...  

The present study was conducted to investigate the effect of dietary copper supplementation on the growth performance, nutrient digestibility and copper metabolism in fattening pigs. A total of 24 pigs (Landrace X Large White X Duroc) with an average initial BW of 30±1.05 kg, the pigs were divided into four treatment groups, with three replicates per treatment and two pigs per replicate, in accordance with a completely randomized design based on the BW. The results indicated that dietary copper supplementation increased the growth performance, CP and EE digestibility. However, there was no significant increase in the DM and OM digestibility. In addition, copper deposition increased with the increase in dietary copper supplementation, while copper absorption, increased with the decrease in dietary copper levels. In conclusion, fattening pigs with 30-60 kg BW can utilize 45-135 mg/kg Cu and porkers at BW of 60-120 kg can also utilize 10-45 mg/kg Cu as CuSO4 for an increased copper utilization and a decreased in copper deposition.


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