Comparative Analysis of Predictive Models for Nongenotoxic Hepatocarcinogenicity Using Both Toxicogenomics and Quantitative Structure–Activity Relationships

Zhichao Liu; Reagan Kelly; Hong Fang; Don Ding; Weida Tong

doi:10.1021/tx2000637

Comparative Analysis of Predictive Models for Nongenotoxic Hepatocarcinogenicity Using Both Toxicogenomics and Quantitative Structure–Activity Relationships

Chemical Research in Toxicology ◽

10.1021/tx2000637 ◽

2011 ◽

Vol 24 (7) ◽

pp. 1062-1070 ◽

Cited By ~ 20

Author(s):

Zhichao Liu ◽

Reagan Kelly ◽

Hong Fang ◽

Don Ding ◽

Weida Tong

Keyword(s):

Comparative Analysis ◽

Predictive Models ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Crystallography, quantitative structure-activity relationships, (QSAR) and molecular graphics in a comparative analysis of the inhibition of dihydrofolate reductase from chicken liver and Lactobacillus casei by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazines

Journal of Medicinal Chemistry ◽

10.1021/jm00368a006 ◽

1984 ◽

Vol 27 (2) ◽

pp. 129-143 ◽

Cited By ~ 36

Author(s):

Corwin Hansch ◽

Bruce A. Hathaway ◽

Zongru Guo ◽

Cynthia Dias Selassie ◽

Stephen W. Dietrich ◽

...

Keyword(s):

Comparative Analysis ◽

Dihydrofolate Reductase ◽

Lactobacillus Casei ◽

Chicken Liver ◽

Quantitative Structure ◽

Molecular Graphics ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative structure–activity relationships (QSAR) for 9-anilinoacridines: a comparative analysis

Chemico-Biological Interactions ◽

10.1016/s0009-2797(98)00085-4 ◽

1998 ◽

Vol 116 (3) ◽

pp. 157-180 ◽

Cited By ~ 11

Author(s):

Hua Gao ◽

William A. Denny ◽

Rajni Garg ◽

Corwin Hansch

Keyword(s):

Comparative Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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ChemInform Abstract: CRYSTALLOGRAPHY, QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS, (QSAR) AND MOLECULAR GRAPHICS IN A COMPARATIVE ANALYSIS OF THE INHIBITION OF DIHYDROFOLATE REDUCTASE FROM CHICKEN LIVER AND LACTOBACILLUS CASEI BY 4,6-DIAMINO-1,2-DIHYDRO

Chemischer Informationsdienst ◽

10.1002/chin.198429224 ◽

1984 ◽

Vol 15 (29) ◽

Author(s):

C. HANSCH ◽

B. A. HATHAWAY ◽

Z. GUO ◽

C. D. SELASSIE ◽

S. W. DIETRICH ◽

...

Keyword(s):

Comparative Analysis ◽

Dihydrofolate Reductase ◽

Lactobacillus Casei ◽

Chicken Liver ◽

Quantitative Structure ◽

Molecular Graphics ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Comparative Analysis of Pharmacophore Features and Quantitative Structure-Activity Relationships for CD38 Covalent and Non-covalent Inhibitors

Chemical Biology & Drug Design ◽

10.1111/cbdd.12606 ◽

2015 ◽

Vol 86 (6) ◽

pp. 1411-1424 ◽

Cited By ~ 12

Author(s):

Shuang Zhang ◽

Xiwen Xue ◽

Liangren Zhang ◽

Lihe Zhang ◽

Zhenming Liu

Keyword(s):

Comparative Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Covalent Inhibitors ◽

Quantitative Structure Activity Relationships

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Quantitative Structure - Activity Relationships (QSARs) of Thrombin Inhibitors: Review, Evaluation and Comparative Analysis

Current Medicinal Chemistry ◽

10.2174/0929867033457935 ◽

2003 ◽

Vol 10 (7) ◽

pp. 525-577 ◽

Cited By ~ 10

Author(s):

Christos Kontogiorgis ◽

Dimitra Hadjipavlou-Litina

Keyword(s):

Comparative Analysis ◽

Thrombin Inhibitors ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Understanding the Molecular Determinant of Reversible Human Monoamine Oxidase B Inhibitors Containing 2H-Chromen-2-One Core: Structure-Based and Ligand-Based Derived Three-Dimensional Quantitative Structure–Activity Relationships Predictive Models

Journal of Chemical Information and Modeling ◽

10.1021/acs.jcim.6b00608 ◽

2017 ◽

Vol 57 (4) ◽

pp. 787-814 ◽

Cited By ~ 13

Author(s):

Milan Mladenović ◽

Alexandros Patsilinakos ◽

Adele Pirolli ◽

Manuela Sabatino ◽

Rino Ragno

Keyword(s):

Monoamine Oxidase ◽

Predictive Models ◽

Three Dimensional ◽

Core Structure ◽

Monoamine Oxidase B ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Molecular Determinant ◽

Quantitative Structure Activity Relationships

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Current Trends in Quantitative Structure Activity Relationships on FXa Inhibitors: Evaluation and Comparative Analysis.

ChemInform ◽

10.1002/chin.200502253 ◽

2005 ◽

Vol 36 (2) ◽

Author(s):

Christos A. Kontogiorgis ◽

Dimitra Hadjipavlou-Litina

Keyword(s):

Comparative Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Current Trends ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative structure-activity relationships (QSAR) for antitumor actmty of nuroazoles: a comparative analysis for the parent compounds and their nitro anxone radical and nitroso anione radical derivatives

5th Korea-Russia International Symposium on Science and Technology. Proceedings. KORUS 2001 (Cat. No.01EX478) ◽

10.1109/korus.2001.975177 ◽

2005 ◽

Author(s):

A. Khlebnikov ◽

I. Schepetkin ◽

Byung Sam Kim ◽

Byoung Se Kwon

Keyword(s):

Comparative Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Current trends in quantitative structure activity relationships on FXa inhibitors: Evaluation and comparative analysis

Medicinal Research Reviews ◽

10.1002/med.20006 ◽

2004 ◽

Vol 24 (6) ◽

pp. 687-747 ◽

Cited By ~ 11

Author(s):

Christos A. Kontogiorgis ◽

Dimitra Hadjipavlou-Litina

Keyword(s):

Comparative Analysis ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Current Trends ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative structure activity relationships (QSAR) for antitumor activity of nitroazoles: a comparative analysis for the parent compounds and their nitroanione radical and nitrosoanione radical derivatives

5th Korea-Russia International Symposium on Science and Technology. Proceedings. KORUS 2001 (Cat. No.01EX478) ◽

10.1109/korus.2001.975012 ◽

2005 ◽

Author(s):

A. Khlebnikov ◽

I. Schepetkin ◽

Byung Sam Kim ◽

Byoung Se Kwon

Keyword(s):

Comparative Analysis ◽

Antitumor Activity ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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