Characterization of Short-Lived Electrophilic Metabolites of the Anticancer Agent Laromustine (VNP40101M)

2011 ◽  
Vol 24 (4) ◽  
pp. 568-578 ◽  
Author(s):  
A-E. F. Nassar ◽  
I. King ◽  
J. Du
Keyword(s):  
Anticancer Agent ◽  
Electrophilic Metabolites

scholarly journals Functional Characterization of an Isoform-Selective Inhibitor of PI3K-p110β as a Potential Anticancer Agent

2012 ◽  
Vol 2 (5) ◽  
pp. 425-433 ◽  
Author(s):  
Jing Ni ◽  
Qingsong Liu ◽  
Shaozhen Xie ◽  
Coby Carlson ◽  
Thanh Von ◽  
...  
Keyword(s):  
Anticancer Agent ◽  
Functional Characterization ◽  
Selective Inhibitor

Characterization of monohydroxylated derivatives of the anticancer agent flavone-8-acetic acid by liquid chromatography with on-line UV and mass spectrometry

2007 ◽  
Vol 21 (20) ◽  
pp. 3373-3386 ◽  
Author(s):  
Minh Hien Pham ◽  
Marie-Claude Menet ◽  
Annabelle Dugay ◽  
Anne Regazzetti ◽  
Daniel Dauzonne ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Acetic Acid ◽  
Liquid Chromatography ◽  
Anticancer Agent ◽  
On Line ◽  
Derivatives Of

Preparation and Characterization of Cyclophosphamide-Loaded Chitosan Microspheres

2012 ◽  
Vol 621 ◽  
pp. 130-133
Author(s):  
Yi Lin Ding ◽  
Su Su Ding ◽  
Guo Fang Ding
Keyword(s):  
Drug Release ◽  
Anticancer Agent ◽  
Loading Rate ◽  
Drug Loading ◽  
Average Diameter ◽  
Uv Spectrophotometry ◽  
Chitosan Microspheres ◽  
Dialysis Bag

Chitosan microspheres were prepared by using a cross linking agent combined with an emulsion technique. Cyclophosphamide was loaded as an anticancer agent. Obtained microspheres were spherical and regular, with a smooth surface morphology, having an average diameter of 15.7±9.0μm. After preparation, the drug-loading rate and entrapment rate of cyclophosphamide was investigated by UV spectrophotometry. Drug release was tested in vitro in a dynamic dialysis system with a dialysis bag. The chitosan microspheres prepared were proved to have good drug release profiles.

Synthesis and characterization of 2-substituted benzimidazoles and their evaluation as anticancer agent

2015 ◽  
Vol 142 ◽  
pp. 286-291 ◽  
Author(s):  
Mohammad Azam ◽  
Azmat Ali Khan ◽  
Saud I. Al-Resayes ◽  
Mohammad Shahidul Islam ◽  
Ajit Kumar Saxena ◽  
...  
Keyword(s):  
Anticancer Agent ◽  
Synthesis And Characterization
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