Quantitative Distinctions of Active Site Molecular Recognition by P-Glycoprotein and Cytochrome P450 3A4

2001 ◽  
Vol 14 (12) ◽  
pp. 1596-1603 ◽  
Author(s):  
Er-jia Wang ◽  
Karen Lew ◽  
Mary Barecki ◽  
Christopher N. Casciano ◽  
Robert P. Clement ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Molecular Recognition ◽  
Active Site ◽  
Cytochrome P450 3A4 ◽  
P Glycoprotein

scholarly journals A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

2000 ◽  
Vol 276 (3) ◽  
pp. 2256-2262 ◽  
Author(s):  
Magang Shou ◽  
Renke Dai ◽  
Dan Cui ◽  
Kenneth R. Korzekwa ◽  
Thomas A. Baillie ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Kinetic Model ◽  
Active Site ◽  
Cytochrome P450 3A4 ◽  
Metabolic Interaction

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4–dependent pharmacokinetics in humans

2006 ◽  
Vol 79 (5) ◽  
pp. 449-460 ◽  
Author(s):  
L BECQUEMONT ◽  
H GLAESER ◽  
S DRESCHER ◽  
M HITZL ◽  
N SIMON ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Ursodeoxycholic Acid ◽  
Cytochrome P450 3A4 ◽  
P Glycoprotein

The Interaction of Selected Phytochemicals, HIV Drugs, and Commercial-Source Herbal Teas and Capsules with Human Cytochrome P450 3A4 and P-glycoprotein

2008 ◽  
Vol 46 (1-2) ◽  
pp. 53-65 ◽  
Author(s):  
Jason W. Budzinski ◽  
Brian C. Foster ◽  
Vance L. Trudeau ◽  
Cathy E. Drouin ◽  
Nana Bafi-Yeboa ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 3A4 ◽  
P Glycoprotein ◽  
Human Cytochrome ◽  
Commercial Source ◽  
Hiv Drugs
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