Reactivity of Glutathione Adducts of 4-(Dimethylamino)phenol. Formation of a Highly Reactive Cyclization Product

1995 ◽  
Vol 8 (2) ◽  
pp. 310-315 ◽  
Author(s):  
Eva Ludwig ◽  
Peter Eyer
Keyword(s):  
Cyclization Product ◽  
Glutathione Adducts

scholarly journals Synthesis of 4-Substituted-1,2-Dihydroquinolines by Means of Gold-Catalyzed Intramolecular Hydroarylation Reaction of N-Ethoxycarbonyl-N-Propargylanilines

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3366
Author(s):  
Antonio Arcadi ◽  
Andrea Calcaterra ◽  
Giancarlo Fabrizi ◽  
Andrea Fochetti ◽  
Antonella Goggiamani ◽  
...  
Keyword(s):  
Building Blocks ◽  
Fine Tuning ◽  
Para Position ◽  
Cyclization Product ◽  
Synthetic Route ◽  
Substituted Anilines ◽  
Novel Approach ◽  
High Yields

An alternative Au(I)-catalyzed synthetic route to functionalized 1,2-dihydroquinolines is reported. This novel approach is based on the use of N-ethoxycarbonyl protected-N-propargylanilines as building blocks that rapidly undergo the IMHA reaction affording the 6-endo cyclization product in good to high yields. In the presence of N-ethoxycarbonyl-N-propargyl-meta-substituted anilines, the regiodivergent cyclization at the ortho-/para-position is achieved by the means of catalyst fine tuning.

scholarly journals Identification of dihydropyrazine-glutathione adducts

2015 ◽  
Vol 40 (4) ◽  
pp. 495-500
Author(s):  
Shinji Takechi ◽  
Shigeru Ito ◽  
Nobuhiro Kashige ◽  
Takumi Ishida ◽  
Tadatoshi Yamaguchi
Keyword(s):  
Glutathione Adducts

Identification of novel glutathione adducts of benzbromarone in human liver microsomes

2017 ◽  
Vol 32 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Naoki Cho ◽  
Kaoru Kobayashi ◽  
Mina Yoshida ◽  
Noriyuki Kogure ◽  
Hiromitsu Takayama ◽  
...  
Keyword(s):  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Glutathione Adducts

Glutathione adducts of N-methyl-4-aminoazobenzene formed in vivo and by reaction of N-benzoyloxy-N-methyl-4-aminoazobenzene with glutathione

1979 ◽  
Vol 25 (1) ◽  
pp. 7-21 ◽  
Author(s):  
Brian Ketterer ◽  
Fred Kadlubar ◽  
Thomas Flammang ◽  
Tom Carne ◽  
Graham Enderby
Keyword(s):  
Glutathione Adducts

Glutathione adducts, not carbamylated lysines, are the major modification of lens α-crystallins from renal failure patients

1995 ◽  
Vol 14 (3) ◽  
pp. 179-188 ◽  
Author(s):  
Jean B. Smith ◽  
G. Adrien Shun-Shin ◽  
Yiping Sun ◽  
Laura R. Miesbauer ◽  
Zhucheng Yang ◽  
...  
Keyword(s):  
Renal Failure ◽  
Glutathione Adducts

scholarly journals Identification of glutathione adducts of α-chlorofatty aldehydes produced in activated neutrophils

2015 ◽  
Vol 56 (5) ◽  
pp. 1014-1024 ◽  
Author(s):  
Mark A. Duerr ◽  
Rajeev Aurora ◽  
David A. Ford
Keyword(s):  
Activated Neutrophils ◽  
Glutathione Adducts
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