Identification of Novel Glutathione Conjugates of Disulfiram and Diethyldithiocarbamate in Rat Bile by Liquid Chromatography-Tandem Mass Spectrometry. Evidence for Metabolic Activation of Disulfiram in vivo

Lixia Jin; Margaret R. Davis; Pei Hu; Thomas A. Baillie

doi:10.1021/tx00040a008

Identification of Novel Glutathione Conjugates of Disulfiram and Diethyldithiocarbamate in Rat Bile by Liquid Chromatography-Tandem Mass Spectrometry. Evidence for Metabolic Activation of Disulfiram in vivo

Chemical Research in Toxicology ◽

10.1021/tx00040a008 ◽

1994 ◽

Vol 7 (4) ◽

pp. 526-533 ◽

Cited By ~ 47

Author(s):

Lixia Jin ◽

Margaret R. Davis ◽

Pei Hu ◽

Thomas A. Baillie

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolic Activation ◽

Tandem Mass ◽

Glutathione Conjugates ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Rat Bile

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In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.8060 ◽

2018 ◽

Vol 32 (6) ◽

pp. 480-488 ◽

Cited By ~ 2

Author(s):

Wenchao Sun ◽

Khoa Dinh Nguyen ◽

William L. Fitch ◽

Samuel D. Banister ◽

Hongxiang Tang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Metabolite Identification ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Identification of in vivo and in vitro metabolites of triptolide by liquid chromatography–tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2012.06.026 ◽

2012 ◽

Vol 70 ◽

pp. 624-630 ◽

Cited By ~ 10

Author(s):

Zhi-hong Peng ◽

Jun-jun Wang ◽

Peng Du ◽

Yong Chen

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Glucosylceramide and Glucosylsphingosine Quantitation by Liquid Chromatography-Tandem Mass Spectrometry to Enable In Vivo Preclinical Studies of Neuronopathic Gaucher Disease

Analytical Chemistry ◽

10.1021/acs.analchem.7b01442 ◽

2017 ◽

Vol 89 (16) ◽

pp. 8288-8295 ◽

Cited By ~ 11

Author(s):

Rick Hamler ◽

Nastry Brignol ◽

Sean W. Clark ◽

Sean Morrison ◽

Leo B. Dungan ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Gaucher Disease ◽

Preclinical Studies ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Identification of in-vivo and in-vitro metabolites of palmatine by liquid chromatography-tandem mass spectrometry

Journal of Pharmacy and Pharmacology ◽

10.1211/jpp/61.05.0014 ◽

2009 ◽

Vol 61 (5) ◽

pp. 647-652

Author(s):

Qian C. Yang ◽

Wen H. Wu ◽

Feng M. Han ◽

Yong Chen

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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DETECTION OF GLUTATHIONE CONJUGATES DERIVED FROM 4-IPOMEANOL METABOLISM IN BILE OF RATS BY LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY

Drug Metabolism and Disposition ◽

10.1124/dmd.104.000406 ◽

2004 ◽

Vol 32 (12) ◽

pp. 1345-1350 ◽

Cited By ~ 13

Author(s):

Teresa M. Alvarez-Diez ◽

Jiang Zheng

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Glutathione Conjugates ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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In vivo metabolism for the hydroxylation of FK778 to the metabolite M3 in humans studied by enantioselective liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.2115 ◽

2005 ◽

Vol 19 (18) ◽

pp. 2681-2688 ◽

Cited By ~ 3

Author(s):

Yu-Luan Chen ◽

Shahzad Akhtar ◽

Hidetsugu Murai ◽

Masakazu Kobayashi

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

In Vivo Metabolism ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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Identification of in-vivo and in-vitro metabolites of palmatine by liquid chromatography-tandem mass spectrometry

Journal of Pharmacy and Pharmacology ◽

10.1211/jpp.61.05.0014 ◽

2009 ◽

Vol 61 (5) ◽

pp. 647-652 ◽

Cited By ~ 18

Author(s):

Qian C. Yang ◽

Wen H. Wu ◽

Feng M. Han ◽

Yong Chen

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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A High-Throughput Assay Using Liquid Chromatography-Tandem Mass Spectrometry for Simultaneous In Vivo Phenotyping of 5 Major Cytochrome P450 Enzymes in Patients

Therapeutic Drug Monitoring ◽

10.1097/ftd.0b013e318197e1bf ◽

2009 ◽

Vol 31 (2) ◽

pp. 239-246 ◽

Cited By ~ 26

Author(s):

Sussan Ghassabian ◽

Manoranjenni Chetty ◽

Bruce N Tattam ◽

MRACI C Chem ◽

John Glen ◽

...

Keyword(s):

Mass Spectrometry ◽

Cytochrome P450 ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Tandem Mass ◽

Cytochrome P450 Enzymes ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

High Throughput Assay

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In vivo microdialysis/liquid chromatography/tandem mass spectrometry for the on-line monitoring of melatonin in rat

Rapid Communications in Mass Spectrometry ◽

10.1002/(sici)1097-0231(19990315)13:5<407::aid-rcm500>3.0.co;2-i ◽

1999 ◽

Vol 13 (5) ◽

pp. 407-411 ◽

Cited By ~ 27

Author(s):

Philip S. H. Wong ◽

K. Yoshioka ◽

F. Xie ◽

P. T. Kissinger

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

In Vivo Microdialysis ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

On Line

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Structural elucidation of in vivo and in vitro metabolites of anisodine by liquid chromatography–tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2007.01.038 ◽

2007 ◽

Vol 44 (3) ◽

pp. 773-778 ◽

Cited By ~ 11

Author(s):

Huaixia Chen ◽

Yong Chen ◽

Peng Du ◽

Fengmei Han

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Structural Elucidation ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

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