Cytochrome P450-mediated oxidation of pentafluorophenol to tetrafluorobenzoquinone as the primary reaction product

1993 ◽  
Vol 6 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Cathaline den Besten ◽  
Peter J. van Bladeren ◽  
Erwin Duizer ◽  
Jacques Vervoort ◽  
Ivonne M. C. M. Rietjens
Keyword(s):  
Cytochrome P450 ◽  
Primary Reaction ◽  
Mediated Oxidation ◽  
Primary Reaction Product

Synthesis of sodalite from Brazilian kaolin wastes

Clay Minerals ◽  
2015 ◽  
Vol 50 (5) ◽  
pp. 663-675 ◽  
Author(s):  
Ana Áurea B. Maia ◽  
Roberto F. Neves ◽  
Rômulo S. Angélica ◽  
Herbert Pöllmann
Keyword(s):  
Clay Mineral ◽  
Bayer Process ◽  
Primary Reaction ◽  
Structural Order ◽  
Complete Reaction ◽  
Low Degree ◽  
Source Materials ◽  
Primary Reaction Product

AbstractKaolin wastes from the Capim and Jari regions (Brazil) were used to produce sodalite under the same conditions used in the Bayer process, in order to control its formation when necessary. Of the two kaolin source materials, the kaolinite from the Jari region was more reactive in the synthesis of sodalite, which is attributed to the low degree of structural order of this clay mineral which increased its reactivity. At a temperature of 150°C and with a Na/Al ratio of 2, although the kaolinite did not react completely, sodalitewas the primary reaction product. An increase in the temperature to 200°C provoked the complete reaction of the kaolinite only for the products in which carbonate and sulfate were used. With a Na/Al ratio >2 and for both of the temperatures, the kaolinite reacted completely to form sodalite.

Modulation of cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADH and cytochrome b5

2014 ◽  
Vol 229 ◽  
pp. S150
Author(s):  
Radek Indra ◽  
Michaela Moserova ◽  
Arlt M. Volker ◽  
Marie Stiborova
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome B5 ◽  
Cytochrome P450 1A1 ◽  
Mediated Oxidation

Generalized cytochrome P450-mediated oxidation and oxygenation reactions in aromatic substrates with activated N-H, O-H, C-H, or S-H substituents

Xenobiotica ◽  
1993 ◽  
Vol 23 (6) ◽  
pp. 633-648 ◽  
Author(s):  
L. Koymans ◽  
G. M. Donné-Op Den Kelder ◽  
J. M. Te Koppele ◽  
N. P. E. Vermeulen
Keyword(s):  
Cytochrome P450 ◽  
Aromatic Substrates ◽  
Mediated Oxidation

Effect of pH on the mechanism of OClO· oxidation of aromatic compounds

2002 ◽  
Vol 80 (7) ◽  
pp. 761-766 ◽  
Author(s):  
Doug Svenson ◽  
John F Kadla ◽  
Hou-min Chang ◽  
Hasan Jameel
Keyword(s):  
Isotope Effect ◽  
Radical Cation ◽  
Chlorine Dioxide ◽  
Kinetic Isotope Effect ◽  
Degradation Products ◽  
Primary Reaction ◽  
Benzyl Alcohols ◽  
Benzyl Radical ◽  
Kinetic Isotope ◽  
Primary Reaction Product

Contrary to previous reports, the reaction mechanism of chlorine dioxide (OClO·) with benzyl alcohols involves both radical cation and benzyl radical mechanisms dependent on pH. The primary reaction product between OClO· and 1-(3,4-dimethoxy-phenyl) ethanol at pH 8 is 3,4-dimethoxyacetophenone. At pH 4 no acetophenone was observed; the majority of the degradation products were chlorinated and aromatic ring-oxidized compounds. A primary kinetic isotope effect (kH/kD = 2.05) was observed in the reaction of OClO· with 1-(3,4-dimethoxy-phenyl)-(1-2H) ethanol at pH 8, but was absent at pH 4 (kH/kD [Formula: see text] 1). Similarly, the corresponding methyl ether (4-(1-methoxy)ethyl-1,2-dimethoxybenzene) was substantially less reactive at pH > 6. On the basis of these results, competing pH-dependent reaction mechanisms have been proposed, where at high pH OClO· reacts with benzyl alcohols via a OClO·–benzyl alcohol complex.Key words: chlorine dioxide, mechanism, kinetic isotope effect, aromatic radical cation, benzyl radical.

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