A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism

1989 ◽  
Vol 2 (1) ◽  
pp. 60-66 ◽  
Author(s):  
Luc Koymans ◽  
Joop H. Van Lenthe ◽  
Ronald Van de Straat ◽  
Gabrielle M. Donne-Op den Kelder ◽  
Nico P. E. Vermeulen
Keyword(s):  
Theoretical Study ◽  
Oxidation Mechanism ◽  
Metabolic Activation ◽  
Cytochrome P 450

Specificity of four forms of cytochrome P-450 in the metabolic activation of several aromatic amines and benzo[a]pyrene

Xenobiotica ◽  
1984 ◽  
Vol 14 (7) ◽  
pp. 549-552 ◽  
Author(s):  
Y. Yamazoe ◽  
M. Shimada ◽  
K. Maeda ◽  
T. Kamataki ◽  
R. Kato
Keyword(s):  
Aromatic Amines ◽  
Metabolic Activation ◽  
Cytochrome P 450

scholarly journals A theoretical study on the formation and oxidation mechanism of hydroxyalkylsulfonate in the atmospheric aqueous phase

RSC Advances ◽  
2019 ◽  
Vol 9 (47) ◽  
pp. 27334-27340 ◽  
Author(s):  
Danna Zhang ◽  
Guochun Lv ◽  
Xiaomin Sun ◽  
Chenxi Zhang ◽  
Zhiqiang Li
Keyword(s):  
Theoretical Calculation ◽  
Aqueous Phase ◽  
Theoretical Study ◽  
Oxidation Mechanism ◽  
Organosulfur Compound

We report the formation of an important organosulfur compound HMS and its oxidation using theoretical calculation.

The role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins

1985 ◽  
Vol 21 (9) ◽  
pp. 1099-1106 ◽  
Author(s):  
J.M.S. van Maanen ◽  
C. de Ruiter ◽  
J. de Vries ◽  
P.R. Kootstra ◽  
F. Gobas ◽  
...  
Keyword(s):  
Hela Cell ◽  
Rat Liver ◽  
Covalent Binding ◽  
Metabolic Activation ◽  
Cytochrome P 450

Experimental and theoretical study on the oxidation mechanism of dopamine in n-octyl pyridinium based ionic liquids–carbon paste modified electrodes

2013 ◽  
Vol 111 ◽  
pp. 846-854 ◽  
Author(s):  
Carlos Díaz ◽  
Camilo García ◽  
Patricio Iturriaga-Vásquez ◽  
Maria Jesús Aguirre ◽  
Juan Pablo Muena ◽  
...  
Keyword(s):  
Ionic Liquids ◽  
Theoretical Study ◽  
Oxidation Mechanism ◽  
Modified Electrodes ◽  
Carbon Paste

Oxidation Mechanism of Si(111)-7 × 7 by Water: A Theoretical Study

2013 ◽  
Vol 117 (30) ◽  
pp. 15763-15772 ◽  
Author(s):  
Xinlan Wang ◽  
Sai Duan ◽  
Xin Xu
Keyword(s):  
Theoretical Study ◽  
Oxidation Mechanism

Metabolic activation of the tricyclic antidepressant amineptine by human liver cytochrome P-450

1987 ◽  
Vol 36 (14) ◽  
pp. 2421-2424 ◽  
Author(s):  
Jean Genève ◽  
Dominique Larrey ◽  
Gilles Amouyal ◽  
Jacques Belghiti ◽  
Dominique Pessayre
Keyword(s):  
Human Liver ◽  
Metabolic Activation ◽  
Tricyclic Antidepressant ◽  
Liver Cytochrome ◽  
Cytochrome P 450
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