Secretome-Based Identification of Mac-2 Binding Protein as a Potential Oral Cancer Marker Involved in Cell Growth and Motility

2008 ◽  
Vol 7 (9) ◽  
pp. 3765-3775 ◽  
Author(s):  
Li-Ping Weng ◽  
Chih-Ching Wu ◽  
Bao-Lian Hsu ◽  
Lang-Ming Chi ◽  
Ying Liang ◽  
...  
Keyword(s):  
Cell Growth ◽  
Oral Cancer ◽  
Binding Protein ◽  
Cancer Marker

Identification of Guanylate-Binding Protein 1 as a Potential Oral Cancer Marker Involved in Cell Invasion Using Omics-Based Analysis

2011 ◽  
Vol 10 (8) ◽  
pp. 3778-3788 ◽  
Author(s):  
Chia-Jung Yu ◽  
Kai-Ping Chang ◽  
Yin-Ju Chang ◽  
Chia-Wei Hsu ◽  
Ying Liang ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Cell Invasion ◽  
Binding Protein ◽  
Cancer Marker ◽  
Guanylate Binding Protein

scholarly journals Critical role of tristetraprolin and AU‐rich element RNA‐binding protein 1 in the suppression of cancer cell growth by globular adiponectin

FEBS Open Bio ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 1964-1976 ◽  
Author(s):  
Nirmala Tilija Pun ◽  
Amrita Khakurel ◽  
Aastha Shrestha ◽  
Sang‐Hyun Kim ◽  
Pil‐Hoon Park
Keyword(s):  
Cell Growth ◽  
Cancer Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Critical Role ◽  
Rna Binding Protein ◽  
Cancer Cell Growth ◽  
Globular Adiponectin

scholarly journals Vitamin A Transporters in Visual Function: A Mini Review on Membrane Receptors for Dietary Vitamin A Uptake, Storage, and Transport to the Eye

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 3987
Author(s):  
Nicasio Martin Ask ◽  
Matthias Leung ◽  
Rakesh Radhakrishnan ◽  
Glenn P. Lobo
Keyword(s):  
Cell Growth ◽  
Vitamin A ◽  
Visual Function ◽  
Binding Protein ◽  
Retinol Binding Protein ◽  
Dietary Vitamin ◽  
Peripheral Tissues ◽  
Retinol Binding Protein 4 ◽  
Retinyl Esters ◽  
And Function

Vitamins are essential compounds obtained through diet that are necessary for normal development and function in an organism. One of the most important vitamins for human physiology is vitamin A, a group of retinoid compounds and carotenoids, which generally function as a mediator for cell growth, differentiation, immunity, and embryonic development, as well as serving as a key component in the phototransduction cycle in the vertebrate retina. For humans, vitamin A is obtained through the diet, where provitamin A carotenoids such as β-carotene from plants or preformed vitamin A such as retinyl esters from animal sources are absorbed into the body via the small intestine and converted into all-trans retinol within the intestinal enterocytes. Specifically, once absorbed, carotenoids are cleaved by carotenoid cleavage oxygenases (CCOs), such as Beta-carotene 15,15’-monooxygenase (BCO1), to produce all-trans retinal that subsequently gets converted into all-trans retinol. CRBP2 bound retinol is then converted into retinyl esters (REs) by the enzyme lecithin retinol acyltransferase (LRAT) in the endoplasmic reticulum, which is then packaged into chylomicrons and sent into the bloodstream for storage in hepatic stellate cells in the liver or for functional use in peripheral tissues such as the retina. All-trans retinol also travels through the bloodstream bound to retinol binding protein 4 (RBP4), where it enters cells with the assistance of the transmembrane transporters, stimulated by retinoic acid 6 (STRA6) in peripheral tissues or retinol binding protein 4 receptor 2 (RBPR2) in systemic tissues (e.g., in the retina and the liver, respectively). Much is known about the intake, metabolism, storage, and function of vitamin A compounds, especially with regard to its impact on eye development and visual function in the retinoid cycle. However, there is much to learn about the role of vitamin A as a transcription factor in development and cell growth, as well as how peripheral cells signal hepatocytes to secrete all-trans retinol into the blood for peripheral cell use. This article aims to review literature regarding the major known pathways of vitamin A intake from dietary sources into hepatocytes, vitamin A excretion by hepatocytes, as well as vitamin A usage within the retinoid cycle in the RPE and retina to provide insight on future directions of novel membrane transporters for vitamin A in retinal cell physiology and visual function.

scholarly journals Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth

PLoS ONE ◽  
2008 ◽  
Vol 3 (4) ◽  
pp. e2002 ◽  
Author(s):  
Zilal Kattan ◽  
Sophie Marchal ◽  
Emilie Brunner ◽  
Carole Ramacci ◽  
Agnès Leroux ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Growth ◽  
Dna Binding ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Binding Protein ◽  
Dna Binding Protein ◽  
Cancer Cell Growth ◽  
Breast Cancer Cell Growth ◽  
Damaged Dna

A Role for the Common GTP-Binding Protein in Coupling of Chromosome Replication to Cell Growth and Cell Division

2002 ◽  
Vol 292 (2) ◽  
pp. 333-338 ◽  
Author(s):  
Aleksandra Sikora-Borgula ◽  
Monika Słomińska ◽  
Piotr Trzonkowski ◽  
Ryszard Zielke ◽  
Andrzej Myśliwski ◽  
...  
Keyword(s):  
Cell Division ◽  
Cell Growth ◽  
Binding Protein ◽  
Chromosome Replication ◽  
Gtp Binding Protein ◽  
Gtp Binding ◽  
The Common

Abstract 3625: Expression of CRBN binding protein AGO2 plays important roles for myeloma cell growth

2015 ◽  
Author(s):  
Qinqin Xu ◽  
Yuexian Hou ◽  
Paul Langlais ◽  
Patrick Erickson ◽  
James Zhu ◽  
...  
Keyword(s):  
Cell Growth ◽  
Binding Protein ◽  
Myeloma Cell
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