Deciphering the Human Brain Proteome: Characterization of the Anterior Temporal Lobe and Corpus Callosum As Part of the Chromosome 15-centric Human Proteome Project

2013 ◽  
Vol 13 (1) ◽  
pp. 147-157 ◽  
Author(s):  
Daniel Martins-de-Souza ◽  
Paulo C. Carvalho ◽  
Andrea Schmitt ◽  
Magno Junqueira ◽  
Fábio C. S. Nogueira ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Human Brain ◽  
Temporal Lobe ◽  
Human Proteome ◽  
Chromosome 15 ◽  
Anterior Temporal Lobe ◽  
Brain Proteome ◽  
Human Proteome Project

Peptidomic analysis of the anterior temporal lobe and corpus callosum from schizophrenia patients

2017 ◽  
Vol 151 ◽  
pp. 97-105 ◽  
Author(s):  
C.C. Café-Mendes ◽  
E.S. Ferro ◽  
A.S. Torrão ◽  
F. Crunfli ◽  
V. Rioli ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Temporal Lobe ◽  
Anterior Temporal Lobe ◽  
Peptidomic Analysis

Identification and Characterization of Proteins Encoded by Chromosome 12 as Part of Chromosome-centric Human Proteome Project

2014 ◽  
Vol 13 (7) ◽  
pp. 3166-3177 ◽  
Author(s):  
Srikanth Srinivas Manda ◽  
Raja Sekhar Nirujogi ◽  
Sneha Maria Pinto ◽  
Min-Sik Kim ◽  
Keshava K. Datta ◽  
...  
Keyword(s):  
Human Proteome ◽  
Chromosome 12 ◽  
Human Proteome Project ◽  
Identification And Characterization

Deciphering the Interregional and Interhemisphere Proteome of the Human Brain in the Context of the Human Proteome Project

2021 ◽  
Author(s):  
Deeptarup Biswas ◽  
Sanjyot Vinayak Shenoy ◽  
Chetanya Chetanya ◽  
Mercedes Lachén-Montes ◽  
Abhilash Barpanda ◽  
...  
Keyword(s):  
Human Brain ◽  
Human Proteome ◽  
Human Proteome Project

scholarly journals Cerebral trauma-induced dyschromatopsia in the left hemifield: case presentation

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yoko Mase ◽  
Yoshitsugu Matsui ◽  
Eriko Uchiyama ◽  
Hisashi Matsubara ◽  
Masahiko Sugimoto ◽  
...  
Keyword(s):  
Visual Field ◽  
Color Vision ◽  
Temporal Lobe ◽  
Fusiform Gyrus ◽  
Ganglion Cell Complex ◽  
Automated Perimetry ◽  
Subjective Symptoms ◽  
Anterior Temporal Lobe ◽  
Case Presentation ◽  
Cerebral Trauma

Abstract Background Acquired color anomalies caused by cerebral trauma are classified as either achromatopsias or dyschromatopsias (Zeki, Brain 113:1721–1777, 1990). The three main brain regions stimulated by color are V1, the lingual gyrus, which was designated as human V4 (hV4), and the fusiform gyrus, designated as V4α. (Zeki, Brain 113:1721–1777, 1990). An acquired cerebral color anomaly is often accompanied by visual field loss (hemi- and quadrantanopia), facial agnosia, prosopagnosia, visual agnosia, and anosognosia depending on the underlying pathology (Bartels and Zeki, Eur J Neurosci 12:172–193, 2000), (Meadows, Brain 97:615–632, 1974), (Pearman et al., Ann Neurol 5:253–261, 1979). The purpose of this study was to determine the characteristics of a patient who developed dyschromatopsia following a traumatic injury to her brain. Case presentation The patient was a 24-year-old woman who had a contusion to her right anterior temporal lobe. After the injury, she noticed color distortion and that blue objects appeared green in the left half of the visual field. Although conventional color vision tests did not detect any color vision abnormalities, short wavelength automated perimetry (SWAP) showed a decrease in sensitivity consistent with a left hemi-dyschromatopsia. Magnetic resonance imaging (MRI) detected abnormalities in the right fusiform gyrus, a part of the anterior temporal lobe. At follow-up 14 months later, subjective symptoms had disappeared, but the SWAP abnormalities persisted and a thinning of the sectorial ganglion cell complex (GCC) was detected. Conclusion The results indicate that although the subjective symptoms resolved early, a reduced sensitivity of SWAP remained and the optical coherence tomography (OCT) showed GCC thinning. We conclude that local abnormalities in the anterior section of fusiform gyrus can cause mild cerebral dyschromatopsia without other symptoms. These findings indicate that it is important to listen to the symptoms of the patient and perform appropriate tests including the SWAP and OCT at the early stage to objectively prove the presence of acquired cerebral color anomaly.

scholarly journals Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Bettina H. Clausen ◽  
Martin Wirenfeldt ◽  
Sofie S. Høgedal ◽  
Lars H. Frich ◽  
Helle H. Nielsen ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Human Brain

scholarly journals Is a gene-centric human proteome project the best way for proteomics to serve biology?

PROTEOMICS ◽  
2010 ◽  
Vol 10 (17) ◽  
pp. 3067-3072 ◽  
Author(s):  
Thierry Rabilloud ◽  
Denis Hochstrasser ◽  
Richard J. Simpson
Keyword(s):  
Human Proteome ◽  
Human Proteome Project
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