scholarly journals Quantitative Proteomic Analysis Revealed N′-Nitrosonornicotine-induced Down-regulation of Nonmuscle Myosin II and Reduced Cell Migration in Cultured Human Skin Fibroblast Cells

2013 ◽  
Vol 12 (3) ◽  
pp. 1282-1288 ◽  
Author(s):  
John M. Prins ◽  
Yinsheng Wang
Keyword(s):  
Cell Migration ◽  
Human Skin ◽  
Proteomic Analysis ◽  
Skin Fibroblast ◽  
Myosin Ii ◽  
Human Skin Fibroblast ◽  
Fibroblast Cells ◽  
Nonmuscle Myosin ◽  
Quantitative Proteomic Analysis ◽  
Nonmuscle Myosin Ii

scholarly journals The possible pre -and post -UVA radiation protective effect of amaranth oil on human skin fibroblast cells

2017 ◽  
Vol 13 (50) ◽  
pp. 339 ◽  
Author(s):  
Katarzyna Wolosik ◽  
Ilona Zareba ◽  
Arkadiusz Surazynski ◽  
Agnieszka Markowska
Keyword(s):  
Protective Effect ◽  
Human Skin ◽  
Skin Fibroblast ◽  
Human Skin Fibroblast ◽  
Fibroblast Cells ◽  
Amaranth Oil ◽  
Uva Radiation

scholarly journals Pathogenesis of Staphylococcus haemolyticus on primary human skin fibroblast cells

Virulence ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 1142-1157 ◽  
Author(s):  
Hala O. Eltwisy ◽  
Medhat Abdel-Fattah ◽  
Amani M. Elsisi ◽  
Mahmoud M. Omar ◽  
Ahmed Aly Abdelmoteleb ◽  
...  
Keyword(s):  
Human Skin ◽  
Skin Fibroblast ◽  
Human Skin Fibroblast ◽  
Fibroblast Cells ◽  
Staphylococcus Haemolyticus

Action of He-Ne laser on wounded human skin fibroblast cells

2019 ◽  
Author(s):  
Vijendra Prabhu ◽  
Satish Rao Bola Sadashiva Sadashiva ◽  
Krishna Kishore Mahato
Keyword(s):  
Human Skin ◽  
Skin Fibroblast ◽  
Human Skin Fibroblast ◽  
Fibroblast Cells

scholarly journals LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration

2017 ◽  
Vol 28 (8) ◽  
pp. 1054-1065 ◽  
Author(s):  
Yu-Hung Lin ◽  
Yen-Yi Zhen ◽  
Kun-Yi Chien ◽  
I-Ching Lee ◽  
Wei-Chi Lin ◽  
...  
Keyword(s):  
Cell Migration ◽  
Hela Cells ◽  
Myosin Ii ◽  
Focal Adhesions ◽  
Stress Fiber ◽  
Stress Fibers ◽  
Actin Stress Fiber ◽  
Nonmuscle Myosin ◽  
Head Region ◽  
Nonmuscle Myosin Ii

Nonmuscle myosin II (NM-II) is an important motor protein involved in cell migration. Incorporation of NM-II into actin stress fiber provides a traction force to promote actin retrograde flow and focal adhesion assembly. However, the components involved in regulation of NM-II activity are not well understood. Here we identified a novel actin stress fiber–associated protein, LIM and calponin-homology domains 1 (LIMCH1), which regulates NM-II activity. The recruitment of LIMCH1 into contractile stress fibers revealed its localization complementary to actinin-1. LIMCH1 interacted with NM-IIA, but not NM-IIB, independent of the inhibition of myosin ATPase activity with blebbistatin. Moreover, the N-terminus of LIMCH1 binds to the head region of NM-IIA. Depletion of LIMCH1 attenuated myosin regulatory light chain (MRLC) diphosphorylation in HeLa cells, which was restored by reexpression of small interfering RNA–resistant LIMCH1. In addition, LIMCH1-depleted HeLa cells exhibited a decrease in the number of actin stress fibers and focal adhesions, leading to enhanced cell migration. Collectively, our data suggest that LIMCH1 plays a positive role in regulation of NM-II activity through effects on MRLC during cell migration.

Muscarinic cholinoceptor activation by pilocarpine triggers apoptosis in human skin fibroblast cells

2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Silvia Reina ◽  
Leonor Sterin-Borda ◽  
Daniela Passafaro ◽  
Enri Borda
Keyword(s):  
Human Skin ◽  
Skin Fibroblast ◽  
Human Skin Fibroblast ◽  
Fibroblast Cells
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