Proteomic Analysis of a Pleistocene Mammoth Femur Reveals More than One Hundred Ancient Bone Proteins

2011 ◽  
Vol 11 (2) ◽  
pp. 917-926 ◽  
Author(s):  
Enrico Cappellini ◽  
Lars J. Jensen ◽  
Damian Szklarczyk ◽  
Aurélien Ginolhac ◽  
Rute A. R. da Fonseca ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Bone Proteins ◽  
Ancient Bone

scholarly journals Proteomic analysis of bone proteins adsorbed onto the surface of titanium dioxide

2016 ◽  
Vol 7 ◽  
pp. 316-322 ◽  
Author(s):  
Keisuke Sugimoto ◽  
Shuhei Tsuchiya ◽  
Masahiro Omori ◽  
Ryo Matsuda ◽  
Masahito Fujio ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Proteomic Analysis ◽  
Bone Proteins

scholarly journals Validation of a Non-Targeted LC-MS Approach for Identifying Ancient Proteins: Method Development on Bone to Improve Artifact Residue Analysis

2015 ◽  
Vol 6 (1) ◽  
pp. 162-174 ◽  
Author(s):  
Andrew Barker ◽  
Jonathan Dombrosky ◽  
Dale Chaput ◽  
Barney Venbles ◽  
Steve Wolverton ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Method Development ◽  
Residue Analysis ◽  
Development Project ◽  
Mass Spectrometry Analysis ◽  
Skeletal Morphology ◽  
Spectrometry Analysis ◽  
Protein Residues ◽  
Bone Proteins ◽  
Ancient Bone

Identification of protein residues from prehistoric cooking pottery using mass spectrometry is challenging because proteins are removed from original tissues, are degraded from cooking, may be poorly preserved due to diagenesis, and occur in a palimpsest of exogenous soil proteins. In contrast, bone proteins are abundant and well preserved. This research is part of a larger method-development project for innovation and improvement of liquid chromatography – mass spectrometry analysis of protein residues from cooking pottery; here we validate the potential of our extraction and characterization approach via application to ancient bone proteins. Because of its preservation potential for proteins and given that our approach is destructive, ancient bone identified via skeletal morphology represents an appropriate verification target. Proteins were identified from zooarchaeological turkey (Meleagris gallopavo Linnaeus Phasianidae), rabbit (Lagomorpha), and squirrel (Sciuridae) remains excavated from ancient pueblo archaeological sites in southwestern Colorado using a non-targeted LC-MS/MS approach. The data have been deposited to the ProteomeXchange Consortium with the dataset identifier PXD002440. Improvement of highly sensitive targeted LC-MS/MS approaches is an avenue for future method development related to the study of protein residues from artifacts such as stone tools and pottery.

895: Proteomic Analysis of Sera from Bladder Cancer Patients with MALDI-TOF-MS

2007 ◽  
Vol 177 (4S) ◽  
pp. 297-297
Author(s):  
Kristina Schwamborn ◽  
Rene Krieg ◽  
Ruth Knüchel-Clarke ◽  
Joachim Grosse ◽  
Gerhard Jakse
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
Proteomic Analysis ◽  
Maldi Tof Ms ◽  
Maldi Tof ◽  
Tof Ms

Proteomic analysis of the anti-obesity effect of Taeumjowui-Tang in high fat diet-induced obese mice

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
E Changkyun Park ◽  
SY Lee ◽  
SH Yun ◽  
WY Kim ◽  
Y Yi ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
High Fat Diet ◽  
Obese Mice ◽  
High Fat

Proteomic analysis of human testicular interstitial fluid reflects disordered spermatogenesis in Klinefelter's syndrome

2014 ◽  
Author(s):  
Robert I McLachlan ◽  
Andrew N Stephens ◽  
Adam Rainczuk ◽  
Caroline Foo ◽  
Mark R Condina ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Interstitial Fluid ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome

Proteomic analysis of nuclear receptor coregulator complexes: II

2013 ◽  
Author(s):  
SY Jung ◽  
A Malovannaya ◽  
J Wei ◽  
BW O'Malley ◽  
J Qin
Keyword(s):  
Nuclear Receptor ◽  
Proteomic Analysis
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