Scalable Enantioseparation of Amino Acid Derivatives Using Continuous Liquid−Liquid Extraction in a Cascade of Centrifugal Contactor Separators

2009 ◽  
Vol 13 (5) ◽  
pp. 911-914 ◽  
Author(s):  
Boelo Schuur ◽  
Andrew J. Hallett ◽  
Jozef G. M. Winkelman ◽  
Johannes G. de Vries ◽  
Hero J. Heeres
Keyword(s):  
Amino Acid ◽  
Liquid Extraction ◽  
Amino Acid Derivatives ◽  
Liquid Liquid Extraction ◽  
Centrifugal Contactor

Continuous Chiral Separation of Amino Acid Derivatives by Enantioselective Liquid−Liquid Extraction in Centrifugal Contactor Separators

2008 ◽  
Vol 12 (5) ◽  
pp. 950-955 ◽  
Author(s):  
Boelo Schuur ◽  
Joelle Floure ◽  
Andrew J. Hallett ◽  
Jozef G. M. Winkelman ◽  
Johannes G. deVries ◽  
...  
Keyword(s):  
Amino Acid ◽  
Chiral Separation ◽  
Liquid Extraction ◽  
Amino Acid Derivatives ◽  
Liquid Liquid Extraction ◽  
Centrifugal Contactor

scholarly journals Hybrid Multiphase CFD Solver for Coupled Dispersed/Segregated Flows in Liquid-Liquid Extraction

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Kent E. Wardle ◽  
Henry G. Weller
Keyword(s):  
Critical Role ◽  
Free Surface Flows ◽  
Liquid Extraction ◽  
Sharp Interface ◽  
Additional Layer ◽  
Liquid Liquid Extraction ◽  
Three Phase ◽  
Phase Liquid ◽  
Centrifugal Contactor ◽  
Dispersed Flows

The flows in stage-wise liquid-liquid extraction devices include both phase segregated and dispersed flow regimes. As a additional layer of complexity, for extraction equipment such as the annular centrifugal contactor, free-surface flows also play a critical role in both the mixing and separation regions of the device and cannot be neglected. Traditionally, computional fluid dynamics (CFD) of multiphase systems is regime dependent—different methods are used for segregated and dispersed flows. A hybrid multiphase method based on the combination of an Eulerian multifluid solution framework (per-phase momentum equations) and sharp interface capturing using Volume of Fluid (VOF) on selected phase pairs has been developed using the open-source CFD toolkit OpenFOAM. Demonstration of the solver capability is presented through various examples relevant to liquid-liquid extraction device flows including three-phase, liquid-liquid-air simulations in which a sharp interface is maintained between each liquid and air, but dispersed phase modeling is used for the liquid-liquid interactions.

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