A Scalable Oxidation for the Final Stage of Synthesis of Cathepsin K Inhibitor SB-462795

2011 ◽  
Vol 15 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Steven N. Goodman ◽  
Qunying Dai ◽  
Jun Wang ◽  
William M. Clark
Keyword(s):  
Final Stage ◽  
Cathepsin K ◽  
Cathepsin K Inhibitor

scholarly journals Protective effects of a cathepsin K inhibitor, SB-553484, in the canine partial medial meniscectomy model of osteoarthritis

2009 ◽  
Vol 17 (9) ◽  
pp. 1236-1243 ◽  
Author(s):  
J.R. Connor ◽  
C. LePage ◽  
B.A. Swift ◽  
D. Yamashita ◽  
A.M. Bendele ◽  
...  
Keyword(s):  
Cathepsin K ◽  
Protective Effects ◽  
Cathepsin K Inhibitor ◽  
Medial Meniscectomy

scholarly journals The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis

2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Erik Lindström ◽  
Biljana Rizoska ◽  
Karin Tunblad ◽  
Charlotte Edenius ◽  
Alison M. Bendele ◽  
...  
Keyword(s):  
Animal Models ◽  
Experimental Animal ◽  
Cathepsin K ◽  
Experimental Animal Models ◽  
Cathepsin K Inhibitor ◽  
Joint Pathology

Treatment with the cathepsin K inhibitor odanacatib in postmenopausal women with low BMD: 5year results of a phase 2 trial

Bone ◽  
2012 ◽  
Vol 51 (6) ◽  
pp. S12
Author(s):  
H. Resch ◽  
N. Binkley ◽  
H. Bone ◽  
J.A. Eisman ◽  
N. Gilchrist ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Cathepsin K ◽  
Phase 2 ◽  
Cathepsin K Inhibitor ◽  
Phase 2 Trial
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