Simple and Efficient Solution-Phase Synthesis of Oligonucleotides Using Extractive Work-Up

Martijn C. de Koning; Amar B. T. Ghisaidoobe; Howard I. Duynstee; Paul B. W. Ten Kortenaar; Dmitri V. Filippov; Gijs A. van der Marel

doi:10.1021/op060133q

Simple and Efficient Solution-Phase Synthesis of Oligonucleotides Using Extractive Work-Up

Organic Process Research & Development ◽

10.1021/op060133q ◽

2006 ◽

Vol 10 (6) ◽

pp. 1238-1245 ◽

Cited By ~ 22

Author(s):

Martijn C. de Koning ◽

Amar B. T. Ghisaidoobe ◽

Howard I. Duynstee ◽

Paul B. W. Ten Kortenaar ◽

Dmitri V. Filippov ◽

...

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis ◽

Work Up

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Efficient solution phase synthesis of 2-(N-acyl)-aminobenzimidazoles

Tetrahedron Letters ◽

10.1016/s0040-4039(02)01754-9 ◽

2002 ◽

Vol 43 (41) ◽

pp. 7303-7306 ◽

Cited By ~ 22

Author(s):

Punit P. Seth ◽

Dale E. Robinson ◽

Elizabeth A. Jefferson ◽

Eric E. Swayze

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis

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ChemInform Abstract: An Efficient Solution Phase Synthesis of Triazadibenzoazulenones: “Designer Isonitrile Free” Methodology Enabled by Microwaves.

ChemInform ◽

10.1002/chin.200932171 ◽

2009 ◽

Vol 40 (32) ◽

Author(s):

Christopher Hulme ◽

Shashi Chappeta ◽

Chris Griffith ◽

Yeon-Sun Lee ◽

Justin Dietrich

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis

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ChemInform Abstract: Efficient Solution Phase Synthesis of 2-(N-Acyl)-aminobenzimidazoles.

ChemInform ◽

10.1002/chin.200251136 ◽

2010 ◽

Vol 33 (51) ◽

pp. no-no

Author(s):

Punit P. Seth ◽

Dale E. Robinson ◽

Elizabeth A. Jefferson ◽

Eric E. Swayze

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis

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ChemInform Abstract: Stereospecific Synthesis of Î²3-Amino Acid Derivatives from Propargylic Alcohols: Efficient Solution-Phase Synthesis of Oligopeptides Without Coupling Agents.

ChemInform ◽

10.1002/chin.200952194 ◽

2009 ◽

Vol 40 (52) ◽

Author(s):

Andrea Temperini ◽

Raffaella Terlizzi ◽

Lorenzo Testaferri ◽

Marcello Tiecco

Keyword(s):

Amino Acid ◽

Efficient Solution ◽

Solution Phase ◽

Stereospecific Synthesis ◽

Coupling Agents ◽

Amino Acid Derivatives ◽

Phase Synthesis ◽

Propargylic Alcohols ◽

Solution Phase Synthesis

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Efficient Solution Phase Synthesis of Oligonucleotide Conjugates Using Protected Biopolymers Containing 3‘-Terminal Alkyl Amines

The Journal of Organic Chemistry ◽

10.1021/jo971511f ◽

1997 ◽

Vol 62 (21) ◽

pp. 7074-7075 ◽

Cited By ~ 12

Author(s):

Dustin L. McMinn ◽

Tracy J. Matray ◽

Marc M. Greenberg

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Alkyl Amines ◽

Solution Phase Synthesis ◽

Oligonucleotide Conjugates

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Efficient Solution-Phase Synthesis of 4,5,7-Trisubstituted Pyrrolo[3,2-d]pyrimidines

ACS Combinatorial Science ◽

10.1021/co300106f ◽

2012 ◽

Vol 15 (1) ◽

pp. 10-19

Author(s):

Weihe Zhang ◽

Jing Liu ◽

Michael A. Stashko ◽

Xiaodong Wang

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis

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An efficient solution phase synthesis of triazadibenzoazulenones: ‘designer isonitrile free’ methodology enabled by microwaves

Tetrahedron Letters ◽

10.1016/j.tetlet.2009.02.099 ◽

2009 ◽

Vol 50 (17) ◽

pp. 1939-1942 ◽

Cited By ~ 35

Author(s):

Christopher Hulme ◽

Shashi Chappeta ◽

Chris Griffith ◽

Yeon-Sun Lee ◽

Justin Dietrich

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis

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Efficient solution phase synthesis and use of multiple O-phosphothreonyl-containing peptides for calcium phosphate binding studies

International journal of peptide & protein research ◽

10.1111/j.1399-3011.1993.tb00335.x ◽

2009 ◽

Vol 41 (3) ◽

pp. 275-281 ◽

Cited By ~ 8

Author(s):

JOHN W. PERICH ◽

DAVID P. KELLY And ◽

ERIC C. REYNOLDS

Keyword(s):

Calcium Phosphate ◽

Efficient Solution ◽

Solution Phase ◽

Phosphate Binding ◽

Binding Studies ◽

Phase Synthesis ◽

Solution Phase Synthesis

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Efficient solution-phase synthesis of multiple O-phosphoseryl-containing peptides related to casein and statherin

International journal of peptide & protein research ◽

10.1111/j.1399-3011.1992.tb01453.x ◽

2009 ◽

Vol 40 (2) ◽

pp. 81-88 ◽

Cited By ~ 22

Author(s):

JOHN W. PERICH ◽

DAVID P. KELLY ◽

ERIC C. REYNOLDS

Keyword(s):

Efficient Solution ◽

Solution Phase ◽

Phase Synthesis ◽

Solution Phase Synthesis

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Parallel Solution-Phase Synthesis of a 2-Aminothiazole Library Including Fully Automated Work-Up

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/138620711794474024 ◽

2011 ◽

Vol 14 (2) ◽

pp. 104-108 ◽

Cited By ~ 3

Author(s):

Hans-Peter Buchstaller ◽

Uwe Anlauf

Keyword(s):

Solution Phase ◽

Phase Synthesis ◽

Parallel Solution ◽

Solution Phase Synthesis ◽

Work Up

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