Eutectic Composition of a Chiral Mixture Containing a Racemic Compound

2005 ◽  
Vol 9 (5) ◽  
pp. 670-676 ◽  
Author(s):  
Yaling Wang ◽  
Rosario LoBrutto ◽  
Robert W. Wenslow ◽  
Ivan Santos
Keyword(s):  
Eutectic Composition ◽  
Racemic Compound

scholarly journals Prediction of the efficiency of diastereoisomer separation on the basis of the behaviour of enantiomeric mixtures

RSC Advances ◽  
2014 ◽  
Vol 4 (41) ◽  
pp. 21254-21261 ◽  
Author(s):  
Emese Pálovics ◽  
Zsolt Szeleczky ◽  
Balázs Fődi ◽  
Ferenc Faigl ◽  
Elemér Fogassy
Keyword(s):  
Eutectic Composition ◽  
Racemic Compound ◽  
Dominant Effect

The composition of a crystalline diastereoisomer (eeDIA) is determined either by the eutectic composition of the racemic compound (eeEuRac) or that of resolving agent (eeEuRes) and the higher ee value has the more dominant effect.

scholarly journals Eutectic Composition of a Chiral Mixture Containing a Racemic Compound

2007 ◽  
Vol 11 (2) ◽  
pp. 293-293
Author(s):  
Yaling Wang ◽  
Rosario LoBrutto ◽  
Robert W. Wenslow ◽  
Ivan Santos
Keyword(s):  
Eutectic Composition ◽  
Racemic Compound

scholarly journals Effect of the Enantiomeric Ratio of Eutectics on the Results and Products of the Reactions Proceeding with the Participation of Enantiomers and Enantiomeric Mixtures

Chemistry ◽  
2020 ◽  
Vol 2 (3) ◽  
pp. 787-795
Author(s):  
Emese Pálovics ◽  
Dorottya Fruzsina Bánhegyi ◽  
Elemér Fogassy
Keyword(s):  
Charge Distribution ◽  
Eutectic Composition ◽  
The Self ◽  
Combined Effect ◽  
Chiral Molecule ◽  
Racemic Compound ◽  
Enantiomeric Ratio

This perspective is focused on the main parameters determining the results of crystallization of enantiomers or enantiomeric mixtures. It was shown that the ratio of supramolecular and helical associations depends on the eutectic composition of the corresponding enantiomeric mixture. The M and P ratios together with the self-disproportionation (SDE) of enantiomers define the reaction of the racemic compound with the resolving agent. Eventually, each chiral molecule reacts with at least two conformers with different degrees of M and P helicity. The combined effect of the configuration, charge distribution, constituent atoms, bonds, flexibility, and asymmetry of the molecules influencing their behavior was also summarized.

scholarly journals Possibilities of Exploiting Kinetic Control in the Continuous Fractional Crystallization of Diastereomeric Mixtures

Symmetry ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1516
Author(s):  
Dorottya Fruzsina Bánhegyi ◽  
Elemér Fogassy ◽  
Emese Pálovics
Keyword(s):  
Fractional Crystallization ◽  
Eutectic Composition ◽  
Kinetic Resolution ◽  
Kinetic Control ◽  
Racemic Compound ◽  
Rapid Crystallization ◽  
Diastereomeric Salts ◽  
Diastereomeric Purity

For rapid and kinetic control-influenced resolutions, it is advisable to choose a resolving agent with the highest possible eutectic composition (eeEuResAg). It may also be advantageous to add the crystalline resolving agent directly to the solution of the racemic compound. In addition, the use of a quasi-racemic resolving agent or amphoteric resolving agent can provide kinetic resolution. In some cases, the continuous fractional crystallization of diastereomeric salts requires the salt of the resolving agent (Ca2+, Na+, etc.) or other achiral additives (thiourea) that cause rapid crystallization and provide high diastereomeric purity. A further advantage may be the sequential use of the same resolving agent that is capable of forming crystalline diastereomers with both enantiomers when using kinetic control (tandem resolution).

Terahertz, infrared and Raman absorption spectra of tyrosine enantiomers and racemic compound

2021 ◽  
pp. 119611
Author(s):  
Meidie Hu ◽  
Mingjie Tang ◽  
Huabin Wang ◽  
Mingkun Zhang ◽  
Shiping Zhu ◽  
...  
Keyword(s):  
Absorption Spectra ◽  
Racemic Compound

Glass Formation and Glass Forming Ability of Alloys Near Eutectic Composition

2000 ◽  
Vol 644 ◽  
Author(s):  
Y. Li
Keyword(s):  
Glass Transition ◽  
Glass Formation ◽  
Eutectic Composition ◽  
Glass Forming Ability ◽  
Critical Section ◽  
Bulk Glass ◽  
Melting Behaviour ◽  
Eutectic Alloys ◽  
Section Thickness ◽  
Glass Forming

AbstractOnset temperature, Tm and offset temperature (liquidus) Tl of melting of a series of bulk glass forming alloys based on La, Mg, and Pd have been measured by studying systematically the melting behaviour of these alloys using DTA or DSC. Bulk metallic glass formation has been found to be most effective at or near their eutectic points and less effective for off-eutectic alloys. Reduced glass transition temperature Trg given by Tg/Tl is found to show a stronger correlation with critical cooling rate or critical section thickness for glass formation than Trg given by Tg/Tm.

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