Phosphine-scavenging Merrifield resins can significantly facilitate the synthesis of highly active Ru metathesis catalysts, including the second-generation Grubbs, Hoveyda, and indenylidene catalysts (GII, HII, InII).
New second generation ruthenium catalysts bearing unsymmetrical NHCs show different catalytic efficiencies depending on the size of the N-alkyl group (methyl or cyclohexyl) and on the backbone configuration.
Fast initiation and high efficiency of ruthenium indenylidene catalysts induced by steric repulsion between two ligands (SIMes ligand and bulky indenylidene ligand).
High-Yield Synthesis of a Long-Sought, Labile Ru-NHC Complex and Its Application to the Concise Synthesis of Second-Generation Olefin Metathesis Catalysts