Reversible displacement of dihydrogen by carbon monoxide in binuclear platinum complexes. Characterization of binuclear carbonyl complexes of platinum(I)

1982 ◽  
Vol 1 (11) ◽  
pp. 1421-1429 ◽  
Author(s):  
John R. Fisher ◽  
Allan J. Mills ◽  
Steven Sumner ◽  
Michael P. Brown ◽  
Mary A. Thomson ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Platinum Complexes ◽  
Carbonyl Complexes

Some tertiary arsine complexes of platinum and palladium

1974 ◽  
Vol 27 (12) ◽  
pp. 2557 ◽  
Author(s):  
Gowda NM Nanje ◽  
GKN Reddy
Keyword(s):  
Carbon Monoxide ◽  
General Formula ◽  
Platinum Complexes ◽  
Carbonyl Complexes ◽  
Square Planar ◽  
Tertiary Arsine ◽  
Square Planar Complexes

A series of square-planar complexes of platinum and palladium of the general formula MX2L2, where M is Pt or Pd, X is Cl, Br or I, and L is EtPh2As or PrPh2As, have been made. The platinum complexes (X = Cl or Br) react with the corresponding halogens to give octahedral complexes of the type PtX4L2. The dichloro complexes of platinum(II) react with carbon monoxide to give carbonyl complexes of the type trans- [PtCl(CO)L2]+. Structures have been assigned to all the compounds.

Synthesis and Characterization of Methyl-Palladium and -Platinum Complexes Supported by N,O- and N,S-Donor Ligands

2016 ◽  
Vol 2016 (6) ◽  
pp. 874-879 ◽  
Author(s):  
Daniel Ruiz Plaza ◽  
José C. Alvarado-Monzón ◽  
Gabriel A. Andreu de Riquer ◽  
Gerardo González-García ◽  
Herbert Höpfl ◽  
...  
Keyword(s):  
Platinum Complexes ◽  
Donor Ligands ◽  
Synthesis And Characterization ◽  
Palladium And Platinum Complexes

Spectroscopic Characterization of Carbon Monoxide Complexes Generated for Copper/Topa Quinone-Containing Amine Oxidases†

Biochemistry ◽  
1999 ◽  
Vol 38 (43) ◽  
pp. 14256-14263 ◽  
Author(s):  
Shun Hirota ◽  
Takahiro Iwamoto ◽  
Katsuyuki Tanizawa ◽  
Osao Adachi ◽  
Osamu Yamauchi
Keyword(s):  
Carbon Monoxide ◽  
Spectroscopic Characterization ◽  
Amine Oxidases ◽  
Topa Quinone

Synthesis of Cyclometallated Platinum Complexes with Substituted Thienylpyridines and Detailed Characterization of Their Luminescence Properties

2009 ◽  
Vol 48 (9) ◽  
pp. 4179-4189 ◽  
Author(s):  
Dmitry N. Kozhevnikov ◽  
Valery N. Kozhevnikov ◽  
Maria M. Ustinova ◽  
Amedeo Santoro ◽  
Duncan W. Bruce ◽  
...  
Keyword(s):  
Platinum Complexes ◽  
Luminescence Properties ◽  
Detailed Characterization

scholarly journals Synthesis, Characterization and Antiproliferative Evaluation of Pt(II) and Pd(II) Complexes with a Thiazine-Pyridine Derivative Ligand

2021 ◽  
Vol 14 (5) ◽  
pp. 395
Author(s):  
Silvia Gutiérrez-Tarriño ◽  
Javier Espino ◽  
Francisco Luna-Giles ◽  
Ana B. Rodríguez ◽  
José A. Pariente ◽  
...  
Keyword(s):  
Cell Lines ◽  
Anticancer Drugs ◽  
Platinum Complexes ◽  
Chemotherapeutic Agents ◽  
Pyridine Derivative ◽  
Cervix Carcinoma ◽  
Multinuclear Complexes ◽  
Histiocytic Lymphoma ◽  
Ovary Adenocarcinoma

Chemical, pharmacological, and clinical research on anticancer coordination complexes has led to noteworthy anticancer drugs such as cisplatin, carboplatin and oxaliplatin. Although these compounds are effective chemotherapeutic agents in the treatment of different tumors, they are associated with high toxicity and numerous side effects. Several studies have shown that the range of platinum complexes with antitumor activity is not limited to structural analogs of cisplatin. Therefore, the development of convenient anticancer drugs that can be effectively used for the treatment of human tumors has become the main goal of most research groups in this field. In this sense, active platinum complexes without NH groups, transplatinum complexes, multinuclear complexes, cationic complexes, and several classes of palladium(II) complexes have emerged. Herein, the synthesis and characterization of two Pt(II) or Pd(II) complexes with PyTz (2-(2-pyridyl)iminotetrahydro-1,3-thiazine), a thiazine derivative ligand, with the formula [MCl2(PyTz)]·C2H6O (M = Pt(II) or Pd(II)) were reported. The potential anticancer ability of both complexes was evaluated in epithelial cervix carcinoma HeLa, human ovary adenocarcinoma SK-OV-3, human histiocytic lymphoma U-937, and human promyelocytic leukemia HL-60 cell lines. Interestingly, the Pt(II) complex showed great cytotoxic potential against all tumor cell lines tested, whereas the Pd(II) complex displayed slight antitumor actions.

Sign in / Sign up

Export Citation Format

Share Document