In Situ and Reactor Study of the Enantioselective Hydrogenation of Acetylacetone by Ruthenium Catalysis with the New Chiral Diphosphine Ligand (R)-(R)-3-Benzyl-2,4-bis(diphenylphosphino)pentane

2000 ◽  
Vol 19 (13) ◽  
pp. 2450-2461 ◽  
Author(s):  
Claudio Bianchini ◽  
Pierluigi Barbaro ◽  
Giancarlo Scapacci ◽  
Fabrizio Zanobini
Keyword(s):  
Enantioselective Hydrogenation ◽  
Diphosphine Ligand ◽  
Ruthenium Catalysis

Asymmetrische Katalysen, 25 [1]. C5H5Mn(CO)2-Komplexe von optisch aktiven Chelatphosphanen als einzähnige Liganden in der enantioselektiven Katalyse / Asymmetric Catalyses, 25 [1]. C5H5Mn(CO)2 Complexes of Optically Active Chelate Phosphanes as Monodentate Ligands in Enantioselective Catalysis

1985 ◽  
Vol 40 (10) ◽  
pp. 1243-1249 ◽  
Author(s):  
Henri Brunner ◽  
Alfons Knott
Keyword(s):  
Cinnamic Acid ◽  
Enantioselective Hydrogenation ◽  
Optically Active ◽  
Enantioselective Catalysis ◽  
Dinuclear Complexes ◽  
Bidentate Ligands ◽  
Monodentate Ligand ◽  
Mononuclear Complexes ◽  
Monodentate Ligands

The chelate phosphanes Diphos, Diop, and Norphos were reacted with C5H5Mn(CO)2THF and CH3C5H4Mn(CO)2THF to give mononuclear complexes, containing the phosphanes as unidentate or as bidentate ligands, and dinuclear complexes, containing bridging phosphane ligands. In C5H5Mn(CO)2Diop one of the two P(C6H5)2 groups of Diop is coordinated to the C5H5Mn(CO)2 fragment; the uncoordinated P(C6H5)2 group makes it a monodentate ligand. C5H5Mn(CO)2Diop together with [Rh(cod)Cl]2 was used as an in situ catalyst in the enantioselective hydrogenation of (Z)-a-[N -acetam ino]cinnamic acid (78.4% ee) and in the enantioselective hydrosilylation of acetophenone with diphenylsilane (6.7% ee).

ChemInform Abstract: A Supramolecularly Tunable Chiral Diphosphine Ligand: Application to Rh and Ir-Catalyzed Enantioselective Hydrogenation.

ChemInform ◽  
2016 ◽  
Vol 47 (45) ◽  
Author(s):  
Xi-Chang Zhang ◽  
Yi-Hu Hu ◽  
Chuan-Fu Chen ◽  
Qiang Fang ◽  
Li-Yao Yang ◽  
...  
Keyword(s):  
Enantioselective Hydrogenation ◽  
Diphosphine Ligand

scholarly journals A supramolecularly tunable chiral diphosphine ligand: application to Rh and Ir-catalyzed enantioselective hydrogenation

2016 ◽  
Vol 7 (7) ◽  
pp. 4594-4599 ◽  
Author(s):  
Xi-Chang Zhang ◽  
Yi-Hu Hu ◽  
Chuan-Fu Chen ◽  
Qiang Fang ◽  
Li-Yao Yang ◽  
...  
Keyword(s):  
Crown Ethers ◽  
Enantioselective Hydrogenation ◽  
Diphosphine Ligand ◽  
Asymmetric Hydrogenations ◽  
High Yields ◽  
Chiral Bisphosphine Ligand

A supramolecularly tunable chiral bisphosphine ligand bearing two pyridyl-containing crown ethers was synthesized and applied in Rh or Ir-catalyzed asymmetric hydrogenations in high yields with excellent ee values (90–99% ee).

ChemInform Abstract: Enantioselective Hydrogenation Reactions with a Full Set of Preformed and Prepared in situ Chiral Diphosphine-Ruthenium(II) Catalysts.

ChemInform ◽  
2010 ◽  
Vol 25 (35) ◽  
pp. no-no
Author(s):  
J. P. GENET ◽  
C. PINEL ◽  
V. RATOVELOMANANA-VIDAL ◽  
S. MALLART ◽  
X. PFISTER ◽  
...  
Keyword(s):  
Enantioselective Hydrogenation ◽  
Hydrogenation Reactions

Enantioselective Transfer Hydrogenation of Oxocarbenium Ions Enables Asymmetric Access to α-Substituted 1,3-Dihydroisobenzofurans

Synthesis ◽  
2021 ◽  
Author(s):  
Lei Liu ◽  
Likai Zhou ◽  
Kuiyong Jia ◽  
xigong Liu
Keyword(s):  
Enantioselective Hydrogenation ◽  
Transfer Hydrogenation ◽  
Oxocarbenium Ions ◽  
High Yields

Reported here is an efficient enantioselective hydrogenation of cyclic oxocarbenium ions generated in situ through collapse of corresponding acetal substrates. The asymmetric approach provides a straightforward access to a variety of chiral α-aryl substituted 1,3-dihydroisobenzofurans in high yields with excellent enantioselectivities.α-Alkynyl substituted 1,3-dihydroisobenzofurans were also proved to be suitable substrates. In addition, when the reaction was performed at gram scale, the desired product was obtained in good yields with excellent enantioselectivity.

In situ monitoring of catalytic three-phase enantioselective hydrogenation using FTIR/ATR spectroscopy

2004 ◽  
Vol 264 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Albin Pintar ◽  
Raluca Malacea ◽  
Catherine Pinel ◽  
Gabriella Fogassy ◽  
Michèle Besson
Keyword(s):  
Enantioselective Hydrogenation ◽  
In Situ Monitoring ◽  
Three Phase ◽  
Atr Spectroscopy

In situ Chiral Modification of Nickel Catalysts for Enantioselective Hydrogenation of Methyl Acetoacetate

2005 ◽  
Vol 70 (10) ◽  
pp. 1642-1652 ◽  
Author(s):  
Lukáš Bartek ◽  
Petr Klusoň ◽  
Libor Červený
Keyword(s):  
Raney Nickel ◽  
Asymmetric Hydrogenation ◽  
Enantioselective Hydrogenation ◽  
Nickel Catalysts ◽  
Methyl Acetoacetate ◽  
Repeated Use ◽  
Series Of Experiments ◽  
Chiral Modification ◽  
Characteristic Features

Chiral modifications of SiO2-supported and Raney nickel catalysts were studied. The catalysts were employed in asymmetric hydrogenation of methyl acetoacetate (MAA) to (R)- and (S)-enantiomers of methyl 3-hydroxybutanoate. The effects of modification parameters such as type and concentration of modifier; presence of a co-modifier and other additives, pH of modification solution on the enantioselectivity of MAA hydrogenation were discussed. Characteristic features of the in situ modification of Ni/SiO2 were also evaluated and the results obtained were compared with the conventional (premodification) approach. Parameters for the conventional and in situ methods were optimised in a series of experiments for both types of catalysts. The in situ modified Ni/SiO2 was found specifically suitable for repeated use due to virtually no decrease in selectivity and activity.

Enantioselective Hydrogenation of α-Ketoesters: An in Situ Surface-Enhanced Raman Spectroscopy (SERS) Study

2011 ◽  
Vol 115 (43) ◽  
pp. 21363-21372 ◽  
Author(s):  
Robert J. Taylor ◽  
Yu Xiong Jiang ◽  
Neil V. Rees ◽  
Gary A. Attard ◽  
Edward L. Jeffery ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Enantioselective Hydrogenation ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman
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