scholarly journals Enantioselective Total Synthesis of (−)-Pironetin: Iterative Aldol Reactions of Thiazolidinethiones

2009 ◽  
Vol 11 (7) ◽  
pp. 1635-1638 ◽  
Author(s):  
Michael T. Crimmins ◽  
Anne-Marie R. Dechert
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Enantioselective Total Synthesis

Enantioselective Total Synthesis of Octalactin A Using Asymmetric Aldol Reactions and a Rapid Lactonization to Form a Medium-Sized Ring.

ChemInform ◽  
2006 ◽  
Vol 37 (15) ◽  
Author(s):  
Isamu Shiina ◽  
Minako Hashizume ◽  
Yu-suke Yamai ◽  
Hiromi Oshiumi ◽  
Takahisa Shimazaki ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Asymmetric Aldol ◽  
Enantioselective Total Synthesis

scholarly journals Application of sequential proline-catalyzed α-chlorination and aldol reactions in the total synthesis of 1-deoxygalactonojirimycin

2018 ◽  
Vol 96 (2) ◽  
pp. 144-147 ◽  
Author(s):  
Michael Meanwell ◽  
Mathew Sutherland ◽  
Robert Britton
Keyword(s):  
Total Synthesis ◽  
Aldol Reaction ◽  
Single Step ◽  
Carbon Skeleton ◽  
Aldol Reactions ◽  
Protecting Group ◽  
One Pot ◽  
Enantioselective Total Synthesis ◽  
Epoxide Opening ◽  
Structural Analogues

A short enantioselective total synthesis of 1-deoxygalactonojirimycin (migalastat) has been achieved that does not rely on chiral pool starting materials or biocatalysis. Instead, this synthesis exploits a one-pot proline-catalyzed α-chlorination and aldol reaction of a commercially available aldehyde to assemble the entire carbon skeleton in a single step. The key role played by a nitrogen protecting group in the final epoxide opening reaction is highlighted as is the amenability to access structural analogues using this route.

Enantioselective Total Synthesis of Octalactin A Using Asymmetric Aldol Reactions and a Rapid Lactonization To Form a Medium-Sized Ring

2005 ◽  
Vol 11 (22) ◽  
pp. 6601-6608 ◽  
Author(s):  
Isamu Shiina ◽  
Minako Hashizume ◽  
Yu-suke Yamai ◽  
Hiromi Oshiumi ◽  
Takahisa Shimazaki ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Asymmetric Aldol ◽  
Enantioselective Total Synthesis

Asymmetric acetate aldol reactions in connection with an enantioselective total synthesis of macrolactin A

1996 ◽  
Vol 37 (49) ◽  
pp. 8949-8952 ◽  
Author(s):  
Ángel González ◽  
Josep Aiguadé ◽  
Félix Urpí ◽  
Jaume Vilarrasa
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Enantioselective Total Synthesis ◽  
Macrolactin A

scholarly journals Enantioselective Total Synthesis of (+)‐Garsubellin A

2021 ◽  
Author(s):  
Dongseok Jang ◽  
Minchul Choi ◽  
Jinglong Chen ◽  
Chulbom Lee
Keyword(s):  
Total Synthesis ◽  
Enantioselective Total Synthesis

Enantioselective Total Synthesis of ( – )‐Spiroxins A, C and D

2021 ◽  
Author(s):  
Xin Shu ◽  
Chong-Chong Chen ◽  
Tao Yu ◽  
Jiayi Yang ◽  
Xiangdong Hu
Keyword(s):  
Total Synthesis ◽  
Enantioselective Total Synthesis

Unified enantioselective total synthesis of 3,6-dioxygenated diketopiperazine natural products, diatretol and lepistamides A, B and C

2021 ◽  
Vol 67 ◽  
pp. 152895
Author(s):  
Shu Takahashi ◽  
Aoi Kimishima ◽  
Tomoyasu Hirose ◽  
Takeshi Yamada ◽  
Akihiro Sugawara ◽  
...  
Keyword(s):  
Natural Products ◽  
Total Synthesis ◽  
Enantioselective Total Synthesis
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