Highly Enantioselective Directsyn- andanti-Aldol Reactions of Dihydroxyacetones Catalyzed by Chiral Primary Amine Catalysts

2008 ◽  
Vol 10 (4) ◽  
pp. 653-656 ◽  
Author(s):  
Sanzhong Luo ◽  
Hui Xu ◽  
Long Zhang ◽  
Jiuyuan Li ◽  
Jin-Pei Cheng
Keyword(s):  
Primary Amine ◽  
Aldol Reactions ◽  
Amine Catalysts

ChemInform Abstract: Highly Enantioselective Direct syn- and anti-Aldol Reactions of Dihydroxyacetones Catalyzed by Chiral Primary Amine Catalysts.

ChemInform ◽  
2008 ◽  
Vol 39 (30) ◽  
Author(s):  
Sanzhong Luo ◽  
Hui Xu ◽  
Long Zhang ◽  
Jiuyuan Li ◽  
Jin-Pei Cheng
Keyword(s):  
Primary Amine ◽  
Aldol Reactions ◽  
Amine Catalysts

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleo-philes to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

scholarly journals Chiral Primary Amine Organocatalysts for Syn-selective Asymmetric Cross-Aldol Reactions

2011 ◽  
Vol 32 (6-8) ◽  
pp. 899-903 ◽  
Author(s):  
Qiang GAO ◽  
Yan LIU ◽  
Shengmei LU ◽  
Can LI
Keyword(s):  
Primary Amine ◽  
Aldol Reactions

ChemInform Abstract: Asymmetric Retro- and Transfer-Aldol Reactions Catalyzed by a Simple Chiral Primary Amine.

ChemInform ◽  
2010 ◽  
Vol 41 (35) ◽  
pp. no-no
Author(s):  
Sanzhong Luo ◽  
Pengxin Zhou ◽  
Jiuyuan Li ◽  
Jin-Pei Cheng
Keyword(s):  
Primary Amine ◽  
Aldol Reactions

Positive Effect of Water in Asymmetric Direct Aldol Reactions with Primary Amine Organocatalyst: Experimental and Computational Studies

2015 ◽  
Vol 10 (10) ◽  
pp. 2112-2116 ◽  
Author(s):  
Shin A. Moteki ◽  
Hiroki Maruyama ◽  
Keiji Nakayama ◽  
Hai-Bei Li ◽  
Galina Petrova ◽  
...  
Keyword(s):  
Primary Amine ◽  
Aldol Reactions ◽  
Computational Studies ◽  
Effect Of Water ◽  
Positive Effect

Regio-, Stereo- and Enantioselective α-Addition of Carbonyl Nucleophiles to Allenamides Catalyzed by a Synergistic Copper/Enamine System

2020 ◽  
Author(s):  
Rémi Blieck ◽  
Sebastien Lemouzy ◽  
Marc Taillefer ◽  
Florian Monnier
Keyword(s):  
Catalytic System ◽  
Secondary Amine ◽  
Primary Amine ◽  
Synergistic Catalysis ◽  
Enantioselective Addition ◽  
Amine Catalysts

A dual copper/enamine catalytic system is found to enable an intermolecular enantioselective α-addition of various carbonyl nucleophiles to allenamides. Secondary amine catalysts allowed the highly enantioselective addition of aldehydes, while using primary amine catalysts led to the enantioselective addition of ketoester nucleophiles. The process was found to be highly regio-, stereo- and enantio-selective and represented the first allene hydrofunctionalization using an synergistic catalysis involving copper

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