Brønsted Acid Accelerated Pd-Catalyzed Direct Asymmetric Allylic Alkylation of Azlactones with Simple Allylic Alcohols: A Practical Access to Quaternary Allylic Amino Acid Derivatives

2014 ◽  
Vol 16 (20) ◽  
pp. 5350-5353 ◽  
Author(s):  
Hui Zhou ◽  
Huameng Yang ◽  
Muwen Liu ◽  
Chungu Xia ◽  
Gaoxi Jiang
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Allylic Alcohols ◽  
Allylic Alkylation ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Asymmetric Allylic Alkylation ◽  
Brönsted Acid

scholarly journals Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction

2019 ◽  
Vol 92 (2) ◽  
pp. 203-209 ◽  
Author(s):  
Danijel Glavač ◽  
Ivanka Jerić ◽  
Matija Gredičak
Keyword(s):  
Reaction Mechanism ◽  
Amino Acid ◽  
Ugi Reaction ◽  
Amino Acid Derivatives ◽  
Acid Catalysts ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid ◽  
Bronsted Acid Catalysts

An organocatalytic interrupted three-component Ugi reaction for the synthesis of α,α–diaryl α–amino acid derivatives is described. The transformation proceeds with a range of isocyanides and 3-aryl isoindolinone alcohols using Brønsted acid catalysts to afford products in good to excellent yields. Based on the obtained results, a reaction mechanism is proposed and discussed.

Auto-oxidation promoted sp3 C–H arylation of glycine derivatives

2018 ◽  
Vol 16 (27) ◽  
pp. 4985-4989 ◽  
Author(s):  
Yuanyuan Wei ◽  
Jie Wang ◽  
Yajun Wang ◽  
Xiaoqiang Yao ◽  
Caixia Yang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Environmentally Benign ◽  
Amino Acid Derivatives ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Reaction Conditions ◽  
Brönsted Acid ◽  
Reaction Proceeds ◽  
Glycine Derivatives

An auto-oxidation promoted sp3 C–H arylation reaction between N-aryl glycine derivatives and electron-rich arenes, leading to the formation of N-aryl α-aryl α-amino acid derivatives, is described. This atom-economical and environmentally benign reaction proceeds smoothly under mild reaction conditions and requires only Brønsted acid and oxygen (balloon). A plausible radical involved mechanism is proposed.

scholarly journals Brønsted Acid-Catalyzed Epimerization-Free Preparation of Dual-Protected Amino Acid Derivatives

ACS Omega ◽  
2017 ◽  
Vol 2 (6) ◽  
pp. 2967-2976 ◽  
Author(s):  
Pedro P. de Castro ◽  
Isabela M. R. Rimulo ◽  
Angelina M. de Almeida ◽  
Renata Diniz ◽  
Giovanni W. Amarante
Keyword(s):  
Amino Acid ◽  
Amino Acid Derivatives ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Protected Amino Acid ◽  
Brönsted Acid ◽  
Acid Catalyzed

Direct Carbohydroxylation of Arylalkenes with Allylic Alcohols: Cooperative Catalysis of Copper, Silver, and a Brønsted Acid

2019 ◽  
Vol 58 (8) ◽  
pp. 2495-2499 ◽  
Author(s):  
Waqar Ahmed ◽  
Sheng Zhang ◽  
Xiaoqiang Yu ◽  
Xiujuan Feng ◽  
Yoshinori Yamamoto ◽  
...  
Keyword(s):  
Allylic Alcohols ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Cooperative Catalysis ◽  
Brönsted Acid

Iridium-Catalyzed C-3 Allylation of Indoles with Allylic Alcohols Promoted by a Brønsted Acid

Synthesis ◽  
2014 ◽  
Vol 46 (13) ◽  
pp. 1717-1724 ◽  
Author(s):  
Chun Cai ◽  
Shu-jie Chen ◽  
Guo-ping Lu
Keyword(s):  
Allylic Alcohols ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid

scholarly journals Chiral phosphine-mediated intramolecular [3 + 2] annulation: enhanced enantioselectivity by achiral Brønsted acid

2017 ◽  
Vol 8 (7) ◽  
pp. 5196-5200 ◽  
Author(s):  
Weijun Yao ◽  
Zhaoyuan Yu ◽  
Shan Wen ◽  
Huanzhen Ni ◽  
Nisar Ullah ◽  
...  
Keyword(s):  
Amino Acid ◽  
Bronsted Acids ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Brönsted Acid

Enantioselective intramolecular [3 + 2] annulation of chalcone–allenes catalyzed by amino acid-derived phosphines and achiral Brønsted acids has been developed.

Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Brønsted Acid Catalysis

Synlett ◽  
2014 ◽  
Vol 25 (15) ◽  
pp. 2149-2254 ◽  
Author(s):  
Gaoxi Jiang ◽  
Huameng Yang ◽  
Hui Zhou ◽  
Hongyu Yin ◽  
Chungu Xia
Keyword(s):  
Acid Catalysis ◽  
Allylic Alcohols ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Highly Efficient ◽  
Brönsted Acid ◽  
Bronsted Acid Catalysis

Direct Carbohydroxylation of Arylalkenes with Allylic Alcohols: Cooperative Catalysis of Copper, Silver, and a Brønsted Acid

2019 ◽  
Vol 131 (8) ◽  
pp. 2517-2521 ◽  
Author(s):  
Waqar Ahmed ◽  
Sheng Zhang ◽  
Xiaoqiang Yu ◽  
Xiujuan Feng ◽  
Yoshinori Yamamoto ◽  
...  
Keyword(s):  
Allylic Alcohols ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Cooperative Catalysis ◽  
Brönsted Acid
Sign in / Sign up

Export Citation Format

Share Document