Rhodium-Catalyzed Direct Annulation of Aldehydes with Alkynes Leading to Indenones: Proceeding through in Situ Directing Group Formation and Removal

2013 ◽  
Vol 15 (18) ◽  
pp. 4754-4757 ◽  
Author(s):  
Shuyou Chen ◽  
Jintao Yu ◽  
Yan Jiang ◽  
Fan Chen ◽  
Jiang Cheng
Keyword(s):  
Group Formation ◽  
Directing Group

Rhodium(iii)-catalyzed indole synthesis at room temperature using the transient oxidizing directing group strategy

2019 ◽  
Vol 55 (64) ◽  
pp. 9547-9550 ◽  
Author(s):  
Yaping Shang ◽  
Krishna Jonnada ◽  
Subhash Laxman Yedage ◽  
Hua Tu ◽  
Xiaofeng Zhang ◽  
...  
Keyword(s):  
Room Temperature ◽  
Nitroso Group ◽  
Group Strategy ◽  
Internal Alkynes ◽  
Directing Group ◽  
Catalyzed Reactions ◽  
Indole Synthesis

Rh-Catalyzed reactions of N-alkyl anilines with internal alkynes at room temperature have been developed using an in situ generated N-nitroso group as a transient oxidizing directing group.

scholarly journals Catalytic C(sp3 )−H Arylation of Free Primary Amines with an exo Directing Group Generated In Situ

2016 ◽  
Vol 55 (31) ◽  
pp. 9084-9087 ◽  
Author(s):  
Yan Xu ◽  
Michael C. Young ◽  
Chengpeng Wang ◽  
David M. Magness ◽  
Guangbin Dong
Keyword(s):  
Primary Amines ◽  
Directing Group

Directed Remote Lateral Metalation: Highly Substituted 2-Naphthols and BINOLs by In Situ Generation of a Directing Group

2018 ◽  
Vol 57 (30) ◽  
pp. 9425-9429 ◽  
Author(s):  
Jignesh J. Patel ◽  
Marju Laars ◽  
Wei Gan ◽  
Johnathan Board ◽  
Matthew O. Kitching ◽  
...  
Keyword(s):  
Directing Group ◽  
In Situ Generation

scholarly journals Low-Valent Tungsten Redox Catalysis Enables Controlled Isomerization and Carbonylative Functionalization of Alkenes

2021 ◽  
Author(s):  
Tanner Jankins ◽  
William Bell ◽  
Yu Zhang ◽  
Zi-Yang Qin ◽  
Milan Gembicky ◽  
...  
Keyword(s):  
Redox Cycle ◽  
Redox Catalysis ◽  
Model Complexes ◽  
History Of ◽  
Internal Site ◽  
Directing Group ◽  
Coordinate Geometry ◽  
Instrumental Role

Tungsten catalysis has played an instrumental role in the history of organometallic chemistry, with electrophilic, fully oxidized W(VI) catalysts featuring prominently in olefin polymerization and metathesis reactions. Here, we report that the simple W(0) precatalyst, W(CO)<sub>6</sub>, catalyzes the isomerization and hydrocarbonylation of alkenes via a W(0)/W(II) redox couple. The 6- to 7-coordinate geometry changes associated with this redox process are key in allowing isomerization to take place over multiple positions and stop at a defined unactivated internal site that is primed for <i>in situ</i> functionalization. DFT studies and crystallographic characterization of multiple directing-group-bound W(II) model complexes illuminate potential intermediates of this redox cycle and showcase the capabilities of the 7-coordinate W(II) geometry to facilitate challenging alkene functionalizations.

ChemInform Abstract: Rhodium(III)-Catalyzed in situ Oxidizing Directing Group-Assisted C-H Bond Activation and Olefination: A Route to 2-Vinylanilines.

ChemInform ◽  
2015 ◽  
Vol 46 (30) ◽  
pp. no-no
Author(s):  
Krishnamoorthy Muralirajan ◽  
Radhakrishnan Haridharan ◽  
Sekar Prakash ◽  
Chien-Hong Cheng
Keyword(s):  
Bond Activation ◽  
Directing Group
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