Soluble Tag-Assisted Peptide Head-to-Tail Cyclization: Total Synthesis of Mahafacyclin B

2013 ◽  
Vol 15 (6) ◽  
pp. 1155-1157 ◽  
Author(s):  
Yuko Fujita ◽  
Shuji Fujita ◽  
Yohei Okada ◽  
Kazuhiro Chiba
Keyword(s):  
Total Synthesis ◽  
Head To Tail Cyclization

Synthesis of Dichotomin A: Use of a Penicillamine-Derived Pseudoproline to Furnish Native Valine Residues

2015 ◽  
Vol 68 (4) ◽  
pp. 627 ◽  
Author(s):  
Michelle S. Y. Wong ◽  
Deni Taleski ◽  
Katrina A. Jolliffe
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Side Chain ◽  
Linear Peptide ◽  
Cyclic Hexapeptide ◽  
Peptide Precursors ◽  
Head To Tail Cyclization

The total synthesis of cyclic hexapeptide dichotomin A from linear peptide precursors containing penicillamine-derived pseudoproline residues is reported. The incorporation of a pseudoproline residue led to a faster reaction and higher head-to-tail cyclization yields in comparison to linear precursors containing the native valine residue. However, deprotection of the pseudoproline resulted in significant amounts of a by-product in which a threonine side chain had undergone dehydration, resulting in a low overall yield of the natural product.

Total synthesis of Δ9(12)-capnellene-8α,10α-diol

1982 ◽  
Vol 23 (52) ◽  
pp. 5471-5474
Author(s):  
G Pattenden
Keyword(s):  
Total Synthesis

Total synthesis of melleumins A and B and their analogs: Determination of stereochemistry and Wnt signal inhibitory activity

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
M Ishibashi ◽  
S Hanazawa ◽  
Y Uchino ◽  
X Li ◽  
MA Arai
Keyword(s):  
Total Synthesis ◽  
Inhibitory Activity ◽  
Wnt Signal

Progress Toward The Total Synthesis Of The Marine Natural Product Karlotoxin 5

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
M Albadry ◽  
Y Zou ◽  
Y Takahashi ◽  
A Waters ◽  
M Hossein ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Natural Product ◽  
Marine Natural Product

Formal Total Synthesis of Clausenamide

Synlett ◽  
1991 ◽  
Vol 1991 (04) ◽  
pp. 343-344
Author(s):  
Takayuki Yakura ◽  
Yukiko Matsumura ◽  
Masazumi Ikeda
Keyword(s):  
Total Synthesis

First Total Synthesis of Narceine Imide

2006 ◽  
Author(s):  
Axel Couture ◽  
Eric Deniau ◽  
Pierre Grandclaudon ◽  
Marc Lamblin
Keyword(s):  
Total Synthesis
Sign in / Sign up

Export Citation Format

Share Document