Three-Component Reaction of Propargyl Amines, Sulfonyl Azides, and Alkynes: One-Pot Synthesis of Tetrasubstituted Imidazoles

2012 ◽  
Vol 14 (24) ◽  
pp. 6266-6269 ◽  
Author(s):  
Zheng Jiang ◽  
Ping Lu ◽  
Yanguang Wang
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
Sulfonyl Azides ◽  
Tetrasubstituted Imidazoles

scholarly journals Copper-Catalyzed One-Pot Synthesis of N-Sulfonyl Amidines from Sulfonyl Hydrazine, Terminal Alkynes and Sulfonyl Azides

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3700
Author(s):  
Yu Zhao ◽  
Zitong Zhou ◽  
Man Chen ◽  
Weiguang Yang
Keyword(s):  
Nucleophilic Addition ◽  
Ring Opening ◽  
Room Temperature ◽  
Terminal Alkynes ◽  
One Pot ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
Sulfonyl Azides ◽  
The Stability

N-Sulfonyl amidines are developed from a Cu-catalyzed three-component reaction from sulfonyl hydrazines, terminal alkynes and sulfonyl azides in toluene at room temperature. Particularly, the intermediate N-sulfonylketenimines was generated via a CuAAC/ring-opening procedure and took a nucleophilic addition with the weak nucleophile sulfonyl hydrazines. In addition, the stability of the product was tested by a HNMR spectrometer.

Novel One-pot Synthesis of Pyranocarbazole Derivatives via an Isocyanide-based Three-component Reaction

2020 ◽  
Vol 17 ◽  
Author(s):  
Visarapu Malathi ◽  
Pedavenkatagari Narayana Reddy ◽  
Pannala Padmaja
Keyword(s):  
Efficient Method ◽  
Atom Economy ◽  
Reaction Conditions ◽  
One Pot ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields

Abstract:: An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole de-rivatives via a three component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedi-carboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.

Isocyanide-based three component reaction for synthesis of highly cyano substituted furan derivatives

RSC Advances ◽  
2016 ◽  
Vol 6 (32) ◽  
pp. 26783-26790 ◽  
Author(s):  
Hamid Reza Safaei ◽  
Farbod Dehbozorgi
Keyword(s):  
Solvent Free ◽  
One Pot ◽  
Furan Derivatives ◽  
Catalyst Free ◽  
One Pot Synthesis ◽  
Three Component Reaction

A rapid and efficient solvent-free one-pot synthesis of novel alkyl amino aryl furan tricarbonitrile derivatives is described under catalyst-free conditions.

ChemInform Abstract: Rhodium Catalyzed Three-Component Reaction of Aldehyde, Boronic Acid, and Sulfonamides: A Facile One-Pot Synthesis of Diarylmethylamines.

ChemInform ◽  
2015 ◽  
Vol 46 (10) ◽  
pp. no-no
Author(s):  
Ponnam Satyanarayana ◽  
Ganapam Manohar Reddy ◽  
Hariharasarma Maheswaran ◽  
Mannepalli Lakshmi Kantam
Keyword(s):  
Boronic Acid ◽  
One Pot ◽  
One Pot Synthesis ◽  
Three Component Reaction

scholarly journals A Facile Synthesis of Polysubstituted Pyrroles by One-Pot Three-Component Reaction

2012 ◽  
Vol 9 (4) ◽  
pp. 2239-2244 ◽  
Author(s):  
Hossein Anaraki-Ardakani ◽  
Maziar Noei ◽  
Mina Karbalaei-Harofteh ◽  
Shahab Zomorodbakhsh
Keyword(s):  
Room Temperature ◽  
Facile Synthesis ◽  
One Pot ◽  
Pyrrole Derivatives ◽  
Dialkyl Acetylenedicarboxylates ◽  
One Pot Synthesis ◽  
Three Component Reaction ◽  
High Yields ◽  
Neutral Conditions

A new and efficient one-pot synthesis of polysubstituted pyrrole derivatives by three-component reaction between dialkyl acetylenedicarboxylates, triphenylphosphine, 2-aminopyridin derivatives in the presence of arylglyoxals is described. The reactions were performed in dichloromethane at room temperature and neutral conditions and afforded high yields of products.

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