Kinetic Resolution of Amines via Dual Catalysis: Remarkable Dependence of Selectivity on the Achiral Cocatalyst

2012 ◽  
Vol 14 (12) ◽  
pp. 3084-3087 ◽  
Author(s):  
Nisha Mittal ◽  
Diana X. Sun ◽  
Daniel Seidel
Keyword(s):  
Kinetic Resolution ◽  
Dual Catalysis

ChemInform Abstract: A Dual-Catalysis/Anion-Binding Approach to the Kinetic Resolution of Allylic Amines.

ChemInform ◽  
2011 ◽  
Vol 42 (36) ◽  
pp. no-no
Author(s):  
Eric G. Klauber ◽  
Nisha Mittal ◽  
Tejas K. Shah ◽  
Daniel Seidel
Keyword(s):  
Kinetic Resolution ◽  
Anion Binding ◽  
Allylic Amines ◽  
Dual Catalysis

A Dual-Catalysis Anion-Binding Approach to the Kinetic Resolution of Amines: Insights into the Mechanism via a Combined Experimental and Computational Study

2015 ◽  
Vol 137 (17) ◽  
pp. 5748-5758 ◽  
Author(s):  
Nisha Mittal ◽  
Katharina M. Lippert ◽  
Chandra Kanta De ◽  
Eric G. Klauber ◽  
Thomas J. Emge ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Computational Study ◽  
Anion Binding ◽  
Dual Catalysis

A dual-catalysis approach to the kinetic resolution of 1,2-diaryl-1,2-diaminoethanes

2012 ◽  
Vol 48 (88) ◽  
pp. 10853 ◽  
Author(s):  
Chang Min ◽  
Nisha Mittal ◽  
Chandra Kanta De ◽  
Daniel Seidel
Keyword(s):  
Kinetic Resolution ◽  
Dual Catalysis

ChemInform Abstract: A Dual-Catalysis Approach to the Kinetic Resolution of 1,2-Diaryl-1,2-diaminoethanes.

ChemInform ◽  
2013 ◽  
Vol 44 (10) ◽  
pp. no-no
Author(s):  
Chang Min ◽  
Nisha Mittal ◽  
Chandra Kanta De ◽  
Daniel Seidel
Keyword(s):  
Kinetic Resolution ◽  
Dual Catalysis

A Dual-Catalysis/Anion-Binding Approach to the Kinetic Resolution of Allylic Amines

2011 ◽  
Vol 13 (9) ◽  
pp. 2464-2467 ◽  
Author(s):  
Eric G. Klauber ◽  
Nisha Mittal ◽  
Tejas K. Shah ◽  
Daniel Seidel
Keyword(s):  
Kinetic Resolution ◽  
Anion Binding ◽  
Allylic Amines ◽  
Dual Catalysis

Synthesis of B-ring-fluorinated (−)-epicatechin gallate derivatives

2020 ◽  
Vol 18 (21) ◽  
pp. 4024-4028
Author(s):  
David D. S. Thieltges ◽  
Kai D. Baumgarten ◽  
Carina S. Michaelis ◽  
Constantin Czekelius
Keyword(s):  
Kinetic Resolution ◽  
Convergent Sequence ◽  
Epicatechin Gallate

Electronically modified, fluorinated catechins and epicatechins are enantioselectively synthesized in a short, convergent sequence via kinetic resolution.

Probing the Parallel Kinetic Resolution of Racemic Oxazolidinones using Quasi-enantiomeric Profens

2006 ◽  
Author(s):  
Jason Eames ◽  
Gregory Coumbarides ◽  
Marco Dingjan ◽  
Tony Flinn ◽  
Northern Northen ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Parallel Kinetic Resolution

Concise Synthesis of GB22 by Endo-Selective Siloxycyclopropane Arylation

2019 ◽  
Author(s):  
Hannah E. Burdge ◽  
Takuya Oguma ◽  
Takahiro Kawajiri ◽  
Ryan Shenvi
Keyword(s):  
Intramolecular Cyclization ◽  
Cross Coupling ◽  
Building Blocks ◽  
Ring Expansion ◽  
Dual Catalysis ◽  
Acid Labile

<div><div><div><p>The first synthesis of GB22 was accomplished by a con- cise, modular route. Two building blocks converged in a novel sp3-sp2 attached-ring coupling that used Ir/Ni dual-catalysis to reverse the regioselectivity of siloxycy- clopropane arylation. This cross-coupling proved general to access β-substituted tetralones via ring-expansion of indanone-derived siloxycyclopropanes. The congested, bridging rings of the GB alkaloids were completed using an aluminum-HFIP complex that effected intramolecular cyclization of an acid-labile substrate.</p></div></div></div>

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