Nucleophilic Addition of β-Amino Carbanions to Arynes: One-Pot Synthesis of 4-Aryl-N-methyl-1,2,3,4-tetrahydroisoquinolines

2012 ◽  
Vol 14 (9) ◽  
pp. 2202-2205 ◽  
Author(s):  
Kamal Nain Singh ◽  
Paramjit Singh ◽  
Pushpinder Singh ◽  
Yadwinder Singh Deol
Keyword(s):  
Nucleophilic Addition ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals Convenient One-Pot Synthesis of Allylsilanes from Enolizable Ketones

SynOpen ◽  
2019 ◽  
Vol 03 (04) ◽  
pp. 138-141
Author(s):  
Man Lung D. Kwan ◽  
Paul R. Challen ◽  
Quynh D.-D. Tran
Keyword(s):  
Nucleophilic Addition ◽  
Slight Modification ◽  
Second Step ◽  
One Pot ◽  
One Pot Synthesis ◽  
Aryl Ketones

A convenient one-pot synthesis of allylsilanes from enolizable methyl aryl ketones has been developed. The first step involves nucleophilic addition of the trimethylsilylmethyl group to ketones using the alkylation method developed by Ishihara with slight modification to generate the corresponding β-silylalkoxides. The second step entails addition of diisobutylaluminum chloride and heating at about 130 °C overnight to afford allylsilanes in fair yields.

The Novel One-Pot Synthesis of Functionalized Vinyl Sulfides Using Triphenylphosphine Catalyzed Nucleophilic Addition of Thiols to Acetylenes

2007 ◽  
Vol 4 (8) ◽  
pp. 567-570 ◽  
Author(s):  
Robabeh Baharfar ◽  
Seyed Baghbanian ◽  
Roghayeh Hossein nia ◽  
Hamid Bijanzadeh
Keyword(s):  
Nucleophilic Addition ◽  
The Novel ◽  
One Pot ◽  
One Pot Synthesis ◽  
Vinyl Sulfides
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