A Straightforward Synthetic Entry to Cleavamine-Type Indole Alkaloids by a Ring-Closing Metathesis−Vinyl Halide Heck Cyclization Strategy

2011 ◽  
Vol 13 (8) ◽  
pp. 2042-2045 ◽  
Author(s):  
M.-Lluïsa Bennasar ◽  
Daniel Solé ◽  
Ester Zulaica ◽  
Sandra Alonso
Keyword(s):  
Indole Alkaloids ◽  
Ring Closing Metathesis ◽  
Heck Cyclization ◽  
Vinyl Halide

Synthesis of cleavamine-type indole alkaloids and their 5-nor derivatives by a ring-closing metathesis–vinyl halide Heck cyclization strategy

Tetrahedron ◽  
2013 ◽  
Vol 69 (12) ◽  
pp. 2534-2541 ◽  
Author(s):  
M.-Lluïsa Bennasar ◽  
Daniel Solé ◽  
Ester Zulaica ◽  
Sandra Alonso
Keyword(s):  
Indole Alkaloids ◽  
Ring Closing Metathesis ◽  
Heck Cyclization ◽  
Vinyl Halide

scholarly journals Sequential ring-closing metathesis–vinyl halide Heck cyclization reactions: access to the tetracyclic ring system of ervitsine

Tetrahedron ◽  
2012 ◽  
Vol 68 (24) ◽  
pp. 4641-4648 ◽  
Author(s):  
M.-Lluïsa Bennasar ◽  
Ester Zulaica ◽  
Daniel Solé ◽  
Sandra Alonso
Keyword(s):  
Ring System ◽  
Cyclization Reactions ◽  
Ring Closing Metathesis ◽  
Heck Cyclization ◽  
Vinyl Halide

Indole alkaloids from Duroia macrophylla (Rubiaceae)

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
CV Nunez ◽  
V Roumy ◽  
DWO Mesquita ◽  
ASS Mesquita ◽  
S Sahpaz ◽  
...  
Keyword(s):  
Indole Alkaloids

Indole alkaloids from plants: Novel structures, bioactivities and preclinical investigations

Planta Medica ◽  
2015 ◽  
Vol 81 (05) ◽  
Author(s):  
XH Cai ◽  
T Feng ◽  
XN Li ◽  
YP Liu ◽  
JH Shang ◽  
...  
Keyword(s):  
Indole Alkaloids ◽  
Novel Structures

A novel class of indole alkaloids isolated from Flindersia pimenteliana (Rutaceae)

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
LP Robertson ◽  
S Duffy ◽  
VM Avery ◽  
AR Carroll
Keyword(s):  
Indole Alkaloids

Nickel-Catalyzed Inter- and Intramolecular Carbon-Sulfur Bond Metathesis by Reversible Arylation

2019 ◽  
Author(s):  
Tristan Delcaillau ◽  
Alessandro Bismuto ◽  
Zhong Lian ◽  
Bill Morandi
Keyword(s):  
Good Yield ◽  
Functional Group ◽  
Product Formation ◽  
Single Bond ◽  
Ring Closing Metathesis ◽  
Catalytic Systems ◽  
Metathesis Reactions ◽  
New Applications ◽  
Further Development ◽  
Sulfur Bond

A nickel-catalyzed carbon-sulfur bond metathesis has been developed to access high-value thioethers. 1,2-bis(dicyclohexylphosphino)ethane (dcype) is essential to promote this highly functional group tolerant reaction. Further, synthetically challenging macrocycles could be obtained in good yield in an unusual example of ring-closing metathesis which does not involve alkene bonds. In-depth organometallic studies support a reversible Ni(0)-Ni(II) pathway to product formation. Overall, this work does not only disclose a more sustainable and more functional group tolerant alternative to previous catalytic systems based on Pd, but also presents new applications and mechanistic information which are highly relevant to the further development and application of unusual single bond metathesis reactions.

Sign in / Sign up

Export Citation Format

Share Document