Formation of Unsymmetrical 1,4-Enediones via A Focusing Domino Strategy: Cross-Coupling of 1,3-Dicarbonyl Compounds and Methyl Ketones or Terminal Aryl Alkenes
A simple, metal free and selective oxidative cross-coupling promoted by I2–DMSO in presence of PTSA has been developed with the use of imidazo[1,2-a]pyridines (1) and methyl ketones (2) to access 3 in a one pot reaction.