Novel Synthesis of the Ortho Ester Derivative of 4,5-Epoxymorphinan

2006 ◽  
Vol 8 (3) ◽  
pp. 523-526 ◽  
Author(s):  
Akio Watanabe ◽  
Toshitsugu Kai ◽  
Hiroshi Nagase
1989 ◽  
Vol 62 (2) ◽  
pp. 455-458 ◽  
Author(s):  
Shigeru Ishii ◽  
Hidenobu Nakayama ◽  
Yasuhiko Yoshida ◽  
Tadataka Yamashita

ChemInform ◽  
1989 ◽  
Vol 20 (24) ◽  
Author(s):  
S. ISHII ◽  
H. NAKAYAMA ◽  
Y. YOSHIDA ◽  
T. YAMASHITA

2000 ◽  
Author(s):  
Thorsten Schroer ◽  
Karl O. Christe
Keyword(s):  

2020 ◽  
Vol 17 (5) ◽  
pp. 396-403
Author(s):  
Nalla Krishna Rao ◽  
Tentu Nageswara Rao ◽  
Botsa Parvatamma ◽  
Y. Prashanthi ◽  
Ravi Kumar Cheedarala

Aims: A series of six 4-benzylidene-2-((1-phenyl-3,4-dihydro isoquinoline-2(1H)-yl)methyloxazol- 5(4H)-one derivatives were synthesized by condensation of substituted aryl aldehydes with 2-(2-(1-phenyl-3,4- dihydro isoquinoline-2(1H)-acetamido)acetic acid in the presence of sodium acetate, acetic anhydride and zinc oxide as catalysts. Background: Novel Synthesis of 4-Benzylidene-2-((1-phenyl-3,4-dihy droisoquinoline-2(1H)-yl)methyl)oxazol- 5(4H)-one derivatives using 1,2,3,Tetrahydroisoquinoline and their antimicrobial activity. Objective: The title compounds can be synthesized from 1,2,3,4-tetrahydroisoquinoline. Methods: The target molecules, i.e., 4-benzylidene-2-((1-phenyl-3, 4-dihydro isoquinoline-2(1H)-yl) methyl) oxazol-5(4H)-one derivatives (8a-8f) have been synthesized from 1,2,3,4-tetrahydroisoquinoline which was prepared from benzoic acid in few steps. Results: All the six compounds were evaluated based on advanced spectral data (1H NMR, 13C NMR & LCMS), and the chemical structures of all compounds were determined by elemental analysis. Conclusion: Antibacterial activity of the derivatives was examined for the synthesized compounds and results indicate that compound with bromine substitution has a good activity profile.


2016 ◽  
Vol 4 (2) ◽  
pp. 109-119 ◽  
Author(s):  
Hanan Al-Lawati ◽  
Mohammad R. Vakili ◽  
Fakhreddin Jamali ◽  
Afsaneh Lavasanifar

RSC Advances ◽  
2021 ◽  
Vol 11 (33) ◽  
pp. 20216-20231
Author(s):  
Ayelén F. Crespi ◽  
Verónica M. Sánchez ◽  
Daniel Vega ◽  
Ana L. Pérez ◽  
Carlos D. Brondino ◽  
...  

The complex chemical functionalization of the aldehyde group was elucidated in copper and cobalt complexes for 4- and 3-pyridinecarboxaldehyde ligands.


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