Applications of 4,4‘-(Me3Si)2-BINAP in Transition-Metal-Catalyzed Asymmetric Carbon−Carbon Bond-Forming Reactions

2005 ◽  
Vol 7 (14) ◽  
pp. 2881-2884 ◽  
Author(s):  
Masamichi Ogasawara ◽  
Helen L. Ngo ◽  
Takeshi Sakamoto ◽  
Tamotsu Takahashi ◽  
Wenbin Lin
Keyword(s):  
Transition Metal ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond ◽  
Bond Forming Reactions ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Asymmetric Carbon

scholarly journals Applications of 4,4′-(Me3Si)2-BINAP in Transition-Metal-Catalyzed Asymmetric Carbon—Carbon Bond-Forming Reactions.

ChemInform ◽  
2005 ◽  
Vol 36 (45) ◽  
Author(s):  
Masamichi Ogasawara ◽  
Helen L. Ngo ◽  
Takeshi Sakamoto ◽  
Tamotsu Takahashi ◽  
Wenbin Lin
Keyword(s):  
Transition Metal ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond ◽  
Bond Forming Reactions ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Asymmetric Carbon

Transition-metal-catalyzed carbon-carbon bond forming reactions: regio- and chemoselective iron(0)-catalyzed diene to olefin cross-coupling reactions

1986 ◽  
Vol 5 (11) ◽  
pp. 2395-2398 ◽  
Author(s):  
James M. Takacs ◽  
Lawrence G. Anderson ◽  
G. V. Bindu. Madhavan ◽  
Mark W. Creswell ◽  
Franklin L. Seely ◽  
...  
Keyword(s):  
Transition Metal ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Carbon Bond ◽  
Bond Forming ◽  
Cross Coupling Reactions ◽  
Carbon Carbon Bond ◽  
Bond Forming Reactions ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

The Stereochemistry of Organometallic Compounds. XXIX. Synthesis of Steroidal 1,4-Diphosphine, 1,3-Diphosphine and 1,6-Diphosphine and Their Evaluation as Ligands in Metal Catalyzed Asymmetric Synthesis

1987 ◽  
Vol 40 (6) ◽  
pp. 1083 ◽  
Author(s):  
RJ Thomson ◽  
WR Jackson ◽  
D Haarburger ◽  
EI Klabunovsky ◽  
VA Pavlov
Keyword(s):  
Asymmetric Synthesis ◽  
Asymmetric Hydrogenation ◽  
Organometallic Compounds ◽  
Carbon Bond ◽  
Bond Forming ◽  
Carbon Carbon Bond ◽  
Bond Forming Reactions ◽  
Hydrogenation Reactions ◽  
Metal Catalyzed ◽  
Asymmetric Carbon

The steroidal 1,4-diphosphines 3α- and 3β-diphenylphosphino-2a-(2'-diphenylphosphinoethyl)-5α-cholestanes and their 5H-benzo[b] phosphindole derivatives have been prepared and shown to be useful ligands in asymmetric hydrogenation reactions. Interestingly the 3α- and 3β-derivatives lead to opposing enantioselection preferences when used in these reactions. A steroidal 1,3-diphosphine, 3α-diphenylphosphino-2α-diphenylphosphinomethyl-5α-cholestane, has been prepared as a mixture containing some of the 3β-epimer. The 3α-1,3-diphosphine led to similar enantioselection in hydrogenation reactions as the 3α-1,4-diphosphine, and a model is proposed to explain the sense of the enantioselectivity in the 1,4- and 1,3-diphosphines. A steroidal 1,6-diphosphine has also been prepared but leads to lower optical yields in the hydrogenation reactions. These ligands have been shown to lead to only poor to moderate optical yields when used in asymmetric carbon-carbon bond forming reactions.

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