Unique Michael Addition-Initiated Domino Reaction for the Stereoselective Synthesis of Functionalized Macrolactones from α-Nitroketones in Water†

2005 ◽  
Vol 7 (11) ◽  
pp. 2197-2200 ◽  
Author(s):  
Giorgio Giorgi ◽  
Sonia Miranda ◽  
Pilar López-Alvarado ◽  
Carmen Avendaño ◽  
Jean Rodriguez ◽  
...  
Keyword(s):  
Michael Addition ◽  
Stereoselective Synthesis ◽  
Domino Reaction

scholarly journals An Enamide‐Based Domino Reaction for a Highly Stereoselective Synthesis of Tetrahydropyrans

2019 ◽  
Vol 58 (37) ◽  
pp. 13056-13059 ◽  
Author(s):  
Philipp Kramer ◽  
Jennifer Grimmer ◽  
Michael Bolte ◽  
Georg Manolikakes
Keyword(s):  
Stereoselective Synthesis ◽  
Domino Reaction

Intercepting the Nazarov Oxyallyl Intermediate with α-Formyl­vinyl Anion Equivalents to Access Formal Morita–Baylis–Hillman Alkylation Products

Synlett ◽  
2017 ◽  
Vol 28 (12) ◽  
pp. 1486-1490 ◽  
Author(s):  
F. West ◽  
Yen-Ku Wu ◽  
Rongrong Lin
Keyword(s):  
Lewis Acid ◽  
Stereoselective Synthesis ◽  
Domino Reaction ◽  
Alkylation Process ◽  
Acid Catalyzed

A Lewis acid catalyzed cationic domino reaction involving sequential electrocyclization and polar addition of allenol ethers onto the resulting oxyallyl species is described. The overall sequence allows a highly stereoselective synthesis of densely substituted cyclopentanoid compounds containing α-formylvinyl functionality which is formally equivalent to products of a Morita–Baylis–Hillman alkylation process.

Stereoselective synthesis of the C-11 to C-19 segment of macrolactin 3 via a center inversion followed by Oxa-Michael addition approach

2017 ◽  
Vol 36 (2-3) ◽  
pp. 100-110
Author(s):  
Prashanth Thodupunuri ◽  
Marumamula Hanumaiah ◽  
Shobanbabu Bommagani ◽  
Gangavaram V. M. Sharma
Keyword(s):  
Michael Addition ◽  
Stereoselective Synthesis

Asymmetric Michael addition between kojic acid derivatives and unsaturated ketoesters promoted by C2-symmetric organocatalysts

2018 ◽  
Vol 16 (48) ◽  
pp. 9314-9318 ◽  
Author(s):  
Alexey A. Kostenko ◽  
Alexander S. Kucherenko ◽  
Andrey N. Komogortsev ◽  
Boris V. Lichitsky ◽  
Sergei G. Zlotin
Keyword(s):  
Tertiary Amine ◽  
Michael Addition ◽  
Kojic Acid ◽  
Domino Reaction ◽  
Asymmetric Michael Addition

An efficient C2-symmetric bifunctional tertiary amine–squaramide organocatalyst for the asymmetric Michael addition/hemiketalization domino reaction of kojic acid derivatives with β,γ-unsaturated α-ketoesters has been designed.

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