Synthesis of New Chiral Monodentate Phosphite Ligands and Their Use in Catalytic Asymmetric Hydrogenation

2003 ◽  
Vol 5 (21) ◽  
pp. 3831-3834 ◽  
Author(s):  
Zihao Hua ◽  
Victor C. Vassar ◽  
Iwao Ojima
Keyword(s):  
Asymmetric Hydrogenation ◽  
Phosphite Ligands ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Hydrogenation

Iridium Complexes with Phosphine−Phosphite Ligands. Structural Aspects and Application in the Catalytic Asymmetric Hydrogenation of N-Aryl Imines

2006 ◽  
Vol 25 (4) ◽  
pp. 961-973 ◽  
Author(s):  
Sergio Vargas ◽  
Miguel Rubio ◽  
Andrés Suárez ◽  
Diego del Río ◽  
Eleuterio Álvarez ◽  
...  
Keyword(s):  
Asymmetric Hydrogenation ◽  
Iridium Complexes ◽  
Phosphite Ligands ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Hydrogenation ◽  
Structural Aspects

scholarly journals Asymmetric Synthetic Strategies of (R)-(–)-Baclofen: An Antispastic Drug

Synthesis ◽  
2017 ◽  
Vol 50 (02) ◽  
pp. 211-226 ◽  
Author(s):  
Perla Ramesh ◽  
Devatha Suman ◽  
Koti Reddy
Keyword(s):  
Asymmetric Reduction ◽  
Asymmetric Hydrogenation ◽  
Asymmetric Aldol ◽  
Asymmetric Michael Addition ◽  
Chemical Resolution ◽  
Enzymatic Desymmetrization ◽  
Catalytic Asymmetric ◽  
Aldol Addition ◽  
Synthetic Approaches ◽  
Catalytic Asymmetric Hydrogenation

Baclofen is an antispastic drug used as a muscle relaxant in the treatment of the paroxysmal pain of trigeminal neuralgia, spasticity of the spinal cord and cerebral origin. Baclofen resides biological activity exclusively in its (R)-(–)-enantiomer. In this review, various asymmetric synthetic strategies for (R)-(–)-baclofen are described.1 Introduction2 Resolution Synthetic Approaches2.1 Chemical Resolution2.2 Biocatalytic Resolution3 Asymmetric Desymmetrization3.1 Catalytic Enantioselective Desymmetrization3.2 Enzymatic Desymmetrization4 Chiral Auxiliary Induced Asymmetric Synthesis4.1 Asymmetric Michael Addition4.2 Asymmetric Aldol Addition4.3 Asymmetric Nucleophilic Substitution5 Asymmetric Reduction5.1 Catalytic Asymmetric Hydrogenation5.2 Bioreduction6 Catalytic Asymmetric Conjugate Addition7 Conclusion

scholarly journals Chiral (Cyclopentadienone)iron Complexes for the Catalytic Asymmetric Hydrogenation of Ketones

2015 ◽  
Vol 2015 (9) ◽  
pp. 1887-1893 ◽  
Author(s):  
Piotr Gajewski ◽  
Marc Renom-Carrasco ◽  
Sofia Vailati Facchini ◽  
Luca Pignataro ◽  
Laurent Lefort ◽  
...  
Keyword(s):  
Asymmetric Hydrogenation ◽  
Iron Complexes ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Hydrogenation

ChemInform Abstract: Catalytic Asymmetric Hydrogenation of Heteroaromatic Compounds, Indoles.

ChemInform ◽  
2000 ◽  
Vol 31 (47) ◽  
pp. no-no
Author(s):  
Ryoichi Kuwano ◽  
Koji Sato ◽  
Takashi Kurokawa ◽  
Daisuke Karube ◽  
Yoshihiko Ito
Keyword(s):  
Asymmetric Hydrogenation ◽  
Heteroaromatic Compounds ◽  
Catalytic Asymmetric ◽  
Catalytic Asymmetric Hydrogenation
Sign in / Sign up

Export Citation Format

Share Document