Total Synthesis of (+)-Geldanamycin and (−)-o-Quinogeldanamycin with Use of AsymmetricAnti-andSyn-Glycolate Aldol Reactions

2002 ◽  
Vol 4 (20) ◽  
pp. 3549-3552 ◽  
Author(s):  
Merritt B. Andrus ◽  
Erik L. Meredith ◽  
Bryon L. Simmons ◽  
B. B. V. Soma Sekhar ◽  
Erik J. Hicken
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions

Total synthesis of pipecolic acid and 1-C-alkyl 1,5-iminopentitol derivatives by way of stereoselective aldol reactions from (S)-isoserinal

2018 ◽  
Vol 16 (7) ◽  
pp. 1118-1125 ◽  
Author(s):  
Sebastian Baś ◽  
Rafał Kusy ◽  
Monika Pasternak-Suder ◽  
Cyril Nicolas ◽  
Jacek Mlynarski ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Asymmetric Synthesis ◽  
Pipecolic Acid ◽  
Aldol Reactions ◽  
Aldol Addition

Asymmetric synthesis of the iminosugar moietyviadiastereoselective aldol addition of a pyruvate, a range of hydroxyketones and (S)-isoserinal, followed by catalytic reductive intramolecular amination.

Total synthesis of (+)-herboxidiene/GEX 1A

2017 ◽  
Vol 15 (8) ◽  
pp. 1842-1862 ◽  
Author(s):  
Alejandro Gómez-Palomino ◽  
Miquel Pellicena ◽  
Katrina Krämer ◽  
Pedro Romea ◽  
Fèlix Urpí ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Efficient Synthesis

An efficient synthesis of herboxidiene is granted from highly stereoselective aldol reactions from two lactate-derived ketones and an oxa-Michael cyclization.

ChemInform Abstract: Highly Enantioselective Mukaiyama Aldol Reactions Catalyzed by a Chiral Oxazaborolidinium Ion: Total Synthesis of (-)-Inthomycin C.

ChemInform ◽  
2011 ◽  
Vol 42 (10) ◽  
pp. no-no
Author(s):  
Bidyut Kumar Senapati ◽  
Lizhu Gao ◽  
Sung Il Lee ◽  
Geum-Sook Hwang ◽  
Do Hyun Ryu
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Mukaiyama Aldol

ChemInform Abstract: Total Synthesis of the Antimicrotubule Agent (+)-Discodermolide Using Boron-Mediated Aldol Reactions of Chiral Ketones.

ChemInform ◽  
2010 ◽  
Vol 31 (13) ◽  
pp. no-no
Author(s):  
Ian Paterson ◽  
Gordon J. Florence ◽  
Kai Gerlach ◽  
Jeremy P. Scott
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Chiral Ketones

ChemInform Abstract: Application of Complex Aldol Reactions to the Total Synthesis of Phorboxazole B.

ChemInform ◽  
2010 ◽  
Vol 32 (7) ◽  
pp. no-no
Author(s):  
David A. Evans ◽  
Duke M. Fitch ◽  
Thomas E. Smith ◽  
Victor J. Cee
Keyword(s):  
Total Synthesis ◽  
Aldol Reactions ◽  
Phorboxazole B

1,6-Asymmetric Induction in Boron-Mediated Aldol Reactions:  Application to a Practical Total Synthesis of (+)-Discodermolide

2003 ◽  
Vol 5 (1) ◽  
pp. 35-38 ◽  
Author(s):  
Ian Paterson ◽  
Oscar Delgado ◽  
Gordon J. Florence ◽  
Isabelle Lyothier ◽  
Jeremy P. Scott ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Asymmetric Induction ◽  
Aldol Reactions

Total Synthesis of (+)-Geldanamycin (I) and (-)-o-Quinogeldanamycin (II): Asymmetric Glycolate Aldol Reactions and Biological Evaluation.

ChemInform ◽  
2004 ◽  
Vol 35 (9) ◽  
Author(s):  
Merritt B. Andrus ◽  
Erik L. Meredith ◽  
Erik J. Hicken ◽  
Bryon L. Simmons ◽  
Russell R. Glancey ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Biological Evaluation ◽  
Aldol Reactions
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