Ni(II)/Zn-Mediated Chemoselective Arylation of Aromatic Aldehydes:  Facile Synthesis of Diaryl Carbinols

2000 ◽  
Vol 2 (15) ◽  
pp. 2295-2298 ◽  
Author(s):  
Kanak Kanti Majumdar ◽  
Chien-Hong Cheng
Keyword(s):  
Aromatic Aldehydes ◽  
Facile Synthesis

scholarly journals Facile synthesis of functionalized tetrahydroquinolines via domino Povarov reactions of arylamines, methyl propiolate and aromatic aldehydes

2012 ◽  
Vol 8 ◽  
pp. 1839-1843 ◽  
Author(s):  
Jing Sun ◽  
Hong Gao ◽  
Qun Wu ◽  
Chao-Guo Yan
Keyword(s):  
Aromatic Aldehydes ◽  
Domino Reaction ◽  
Facile Synthesis ◽  
Methyl Propiolate ◽  
Toluenesulfonic Acid ◽  
Povarov Reaction

In the presence of p-toluenesulfonic acid as catalyst the domino reaction of arylamines, methyl propiolates and aromatic aldehydes in ethanol proceeded smoothly to give polysubstituted 1,2,3,4-tetrahydroquinolines in moderate yields. The reaction is believed to involve the Povarov reaction of in situ generated β-enamino ester with the in situ formed aromatic imine.

scholarly journals A Facile Synthesis ofN-H- andN-Substituted Acridine-1,8-diones under Sonic Condition

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
S. Sudha ◽  
M. A. Pasha
Keyword(s):  
Ammonium Nitrate ◽  
Energy Efficient ◽  
Aromatic Amines ◽  
Ammonium Acetate ◽  
Aromatic Aldehydes ◽  
Ceric Ammonium Nitrate ◽  
Facile Synthesis ◽  
One Pot

Synthesis of an assembly of structurally importantN-H- andN-substituted acridine-1,8-diones by CAN (ceric ammonium nitrate) catalysed one-pot four-component reaction of electron-deficient and electron-rich aromatic aldehydes and aromatic amines or ammonium acetate and dimedone or cyclohexyl-1,3-diones at 26°C under sonic condition is reported. The method is clean and energy efficient as it uses a greener method and an eco-friendly catalyst.

scholarly journals A Facile Synthesis and Biological Screening of Pyrimidine Derivatives under Ultrasonic Irradiations by ZnCr2O4 Nano-Particles Catalyst

2021 ◽  
Vol 11 (1) ◽  
pp. 2996-3005
Keyword(s):  
Biological Activities ◽  
Aromatic Aldehydes ◽  
Vital Role ◽  
Nano Particles ◽  
Facile Synthesis ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
Biological Screening ◽  
Characterization Methods ◽  
The One

Using a recyclable catalyst, facile synthesis of pyrimidine derivatives (4a-e) is attributed through the one-pot multi-component reaction of 2-amino benzimidazole (1) substituted aromatic aldehydes (2a-e) with malononitrile (3) under ultrasonic irradiations. Synthesized derivatives might help society in getting more active pharmaceutical constituents. In this present work, series of substituted pyrimidine (4a-e) were synthesized and confirmed with different spectra characterization methods. The ZnCr2O4 nano-particles play a vital role in eco-friendly, highly efficient, recyclable heterogeneous nanocatalyst. Furthermore, synthesized pyrimidine derivatives showed significant biological activities. Advantages of this handy route are less reaction time, simple isolation, and highly yielded products.

scholarly journals Efficient and Facile Synthesis of Chromenopyrano[2,3-b] pyridine Derivatives Catalyzed by Sodium Carbonate

2021 ◽  
Vol 68 (2) ◽  
pp. 332-340
Author(s):  
Raziyeh Keshavarz ◽  
Mahnaz Farahi ◽  
Bahador Karami
Keyword(s):  
Sodium Carbonate ◽  
Aromatic Aldehydes ◽  
Dimethyl Acetylenedicarboxylate ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
Bioactive Heterocycles ◽  
High Yields ◽  
Silica Sodium Carbonate

In this research, a number of new and known chromenopyrano[2,3-b]pyridine derivatives have been prepared. Initially, according to the reported procedure, pyrano[2,3-c]chromene derivatives were synthesized by the reaction between 4-hydroxycoumarin, aromatic aldehydes and malononitrile using silica sodium carbonate (SSC) as the catalyst. Next, the prepared pyrano[2,3-c]chromenes were reacted by dimethyl acetylenedicarboxylate (DMAD) or cyclohexanone in the presence of sodium carbonate to produce chromenopyrano[2,3-b]pyridine derivatives. The presented protocol avoids the use of expensive catalysts and gives useful potentially bioactive heterocycles in excellent to high yields.

Green and Facile Synthesis of Pyrimidine Derivatives Using Choline Chloride-urea Mixture as a Deep Eutectic Solvent or Cerium (IV) Ammonium Nitrate

2019 ◽  
Vol 23 (16) ◽  
pp. 1771-1777 ◽  
Author(s):  
Mohamed S. Behalo ◽  
Abdelmotaal Abdelmajeid ◽  
Aly A. Aly ◽  
Kaouser A. Hebash ◽  
Enas A. Mohamed
Keyword(s):  
Ammonium Nitrate ◽  
Choline Chloride ◽  
Deep Eutectic Solvent ◽  
Aromatic Aldehydes ◽  
Structural Formula ◽  
Facile Synthesis ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
High Yields ◽  
Cerium Iv Ammonium Nitrate

An efficient and facile synthesis of substituted pyrimidine derivatives through Biginelli type reaction was achieved in high yields via one-pot reaction of aromatic aldehydes, active methylene compounds and urea or thiourea in the presence of choline chloride- urea mixture as a deep eutectic solvent or cerium (IV) ammonium nitrate (CAN) as a catalyst at different conditions. The reaction was carried out using different ratio of CAN in different solvents to determine the optimum conditions. In addition, 2-mercapto-6-oxo- 4-(thiophen-2-yl)-1,6-dihydropyrimidine-5-carbonitrile was employed in the synthesis of pyrimidinylhydrazide and its corresponding hydrazone. The structural formula of all derivatives was confirmed and characterized by their elemental analyses and spectral data (IR, MS, 1H NMR, 13C NMR).

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